SYSTEMS AND METHODS FOR GENERATING AN ARTIFICIAL PHOTOPLETHYSMOGRAPH SIGNAL

• US 20140244205A1
• Filed: 02/27/2013
• Published: 08/28/2014
• Est. Priority Date: 02/27/2013
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Van Slyke, Braddon M., McGonigle, Scott, Mestek, Michael, Addison, Paul Stanley, Watson, James Nicholas, Kadlec, Ronald
• Granted Patent: US 9,554,712 B2
• Time in Patent Office: Days
• US Class Current: 702/124
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/7278 Artificial waveform generation or derivation, e.g. synthesising signals from measured signals A61B5/327 takes precedence

Abstract

A test unit may generate a pulse signal based on a pulsatile profile and a frequency modulation component of a respiratory profile. A respiration modulated signal may be generated from the pulse signal, an amplitude modulation component, and a baseline modulation component. A patient modulated signal may be generated based on the respiration modulated signal and a patient profile. The artificial PPG signal may be generated based on the patient modulated signal and an artifact profile. The artificial PPG signal may be output to an electronic device.

Claims

1. A method for generating an artificial photoplethysmograph (PPG) signal, the method comprising:

generating, using the processing equipment, a frequency modulation component, an amplitude modulation component, and a baseline modulation component based on a respiratory profile;

generating, using processing equipment, a pulse signal based on a pulsatile profile and the frequency modulation component;

modifying, using the processing equipment, the pulse signal based at least in part on the amplitude modulation component and the baseline modulation component to generate a respiration modulated signal; and

outputting the artificial PPG signal based at least in part on the respiration modulated signal.

2. The method of claim 1, wherein generating the pulse signal comprises:

generating a heart rate signal based on the pulsatile profile and the frequency modulation component;

generating a dichrotic notch signal based on the pulsatile profile and the frequency modulation component; and

combining the heart rate signal and the dichrotic notch signal.

3. The method of claim 1, wherein modifying the pulse signal comprises:

multiplying, with a multiplier, the pulse signal and the amplitude modulation component; and

combining, with an adder, the pulse signal and the baseline modulation component to generate the respiration modulated signal.

4. The method of claim 3, further comprising modifying the respiration modulated signal based on a patient profile to generate a patient modulated signal.

5. The method of claim 4, further comprising modifying the patient modulated signal based on an artifact profile to generate the artificial PPG signal.

6. The method of claim 5, wherein the pulsatile profile, respiratory profile, patient profile, and artifact profile are generated based on inputs to a parameter selection interface.

7. The method of claim 1, wherein outputting the artificial PPG signal comprises outputting the artificial PPG signal to a physiological monitor.

8. A non-transitory computer-readable storage medium for providing an artificial photoplethysmograph (PPG) signal to an electronic device, the computer-readable medium having computer program instructions recorded thereon for:

generating a frequency modulation component, an amplitude modulation component, and a baseline modulation component based on a respiratory profile;

generating a pulse signal based on a pulsatile profile and the frequency modulation component;

modifying the pulse signal based at least in part on the amplitude modulation component and the baseline modulation component to generate a respiration modulated signal; and

outputting the artificial PPG signal based at least in part on the respiration modulated signal.

9. The computer-readable medium of claim 8, wherein generating the pulse signal comprises:

generating a heart rate signal based on the pulsatile profile and the frequency modulation component;

generating a dichrotic notch signal based on the pulsatile profile and the frequency modulation component; and

combining the heart rate signal and the dichrotic notch signal.

10. The computer-readable medium of claim 8, wherein modifying the pulse signal comprises:

multiplying, with a multiplier, the pulse signal and the amplitude modulation component; and

combining, with an adder, the pulse signal and the baseline modulation component to generate the respiration modulated signal.

11. The computer-readable medium of claim 10, further comprising modifying the respiration modulated signal based on a patient profile to generate a patient modulated signal.

12. The computer-readable medium of claim 11, further comprising modifying the patient modulated signal based on an artifact profile to generate the artificial PPG signal.

13. The computer-readable medium of claim 12, wherein wherein the pulsatile profile, respiratory profile, patient profile, and artifact profile are generated based on inputs to a parameter selection interface.

14. A test unit comprising processing equipment configured to:

generate a frequency modulation component, an amplitude modulation component, and a baseline modulation component based on a respiratory profile;

generate a pulse signal based on a pulsatile profile and the frequency modulation component;

modify the pulse signal based at least in part on the amplitude modulation component and the baseline modulation component to generate the artificial PPG signal; and

output the artificial PPG signal.

15. The test unit of claim 14, wherein the test unit is configured to:

generate a heart rate signal based on the pulsatile profile and the frequency modulation component;

generate a dichrotic notch signal based on the pulsatile profile and the frequency modulation component; and

combine the heart rate signal and the dichrotic notch signal.

16. The test unit of claim 14, wherein the test unit is configured to:

multiply, with a multiplier, the pulse signal and the amplitude modulation component; and

combine, with an adder, the pulse signal and the baseline modulation component to generate the respiration modulated PPG signal.

17. The test unit of claim 16, wherein the test unit is further configured to modify the respiration modulated signal based on a patient profile to generate a patient modulated signal.

18. The test unit of claim 17, wherein the test unit is further configured to modify the patient modulated signal based on an artifact profile to generate the artificial PPG signal.

19. The test unit of claim 18, wherein the pulsatile profile, respiratory profile, patient profile, and artifact profile are generated based on inputs to a parameter selection interface.

20. The test unit of claim 14, wherein the artificial PPG signal is output to a physiological monitor.