METHODS AND SYSTEMS FOR DOSING CONTROL IN AN AUTOMATED FLUID DELIVERY SYSTEM

• US 20140248159A1
• Filed: 03/04/2013
• Published: 09/04/2014
• Est. Priority Date: 03/04/2013
• Status: Active Grant

• Current Assignee: Bayer Healthcare LLC (Bayer AG)
• Original Assignee: Medrad Incorporated (Bayer AG)
• Inventors: MARSH, Charles, McCUTCHAN, Larry
• Granted Patent: US 9,109,591 B2
• Time in Patent Office: Days
• US Class Current: 417/53
• CPC Class Codes: A61M 2205/33 Controlling, regulating or measuring
• CPC Class Codes: A61M 2205/3379 Masses, volumes, levels of fluids in reservoirs, flow rates
• CPC Class Codes: A61M 2205/505 Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 5/14228 with linear peristaltic action, i.e. comprising at least three pressurising members or a helical member
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: F04B 43/02 having plate-like flexible members, e.g. diaphragms F04B43/14 takes precedence
• CPC Class Codes: F04B 43/12 having peristaltic action
• CPC Class Codes: F04B 43/14 having plate-like flexible members
• CPC Class Codes: F04B 49/065 and making use of computers
• CPC Class Codes: F04B 49/106 Responsive to pumped volume

Abstract

Methods and systems for dispensing a fluid using an automated fluid delivery system are disclosed. A pump may be configured to force an aliquot of fluid into a fluid delivery channel. A processor may receive values of a property for the aliquot and the source of the aliquot. The processor may use the values to determine the volume of the aliquot. The determined volume is compared by the processor against an expected volume to establish the amount of fluid being pumped by the pump per unit, such as time or revolutions. The processor controls operation of the pump to dispense a predetermined dose based on the amount of fluid being pumped by the pump per unit.

Claims

1. A system for dispensing a fluid, comprising:

a pump configured to force an aliquot of fluid from a fluid source into a fluid delivery channel;

at least one sensor configured to measure a sample value of a property of the aliquot;

a processor in communication with the pump and the sensor; and

a non-transitory, computer-readable storage medium in operable communication with the processor, wherein the computer-readable storage medium contains one or more programming instructions that, when executed, cause the processor to;

receive the sample value,

receive a source value of the property for the fluid source,

determine a volume of the aliquot based on a comparison of the sample value and the source value, and

control operation of the pump to dispense a predetermined dose of the fluid based on a comparison of the sample volume with an expected volume.

2. The system of claim 1, wherein the computer-readable storage medium further contains one or more programming instructions that, when executed, cause the processor to determine a pump coefficient based on the comparison of the sample volume with the expected volume, the pump coefficient being configured to indicate a volume of fluid forced into the fluid delivery channel per unit.

3. The system of claim 2, wherein the pump coefficient comprises a volume-per-time coefficient.

4. The system of claim 2, wherein the pump coefficient comprises a volume-per-revolution coefficient.

5. The system of claim 2, wherein the one or more programming instructions that, when executed, cause the processor to control operation of the pump further comprise one or more programming instructions that, when executed, cause the processor to control the pump using the pump coefficient.

6. The system of claim 2 wherein the one or more programming instructions that, when executed, cause the processor to control operation of the pump further comprise one or more programming instructions that, when executed, cause the processor to adjust the pump coefficient to correspond with dispensing the predetermined dose.

7. The system of claim 1, wherein the expected volume comprises a volume of the fluid forced by the pump under standard conditions.

8. The system of claim 1, wherein the fluid is selected from one of the following:

saline, chemotherapy drugs, radiopharmaceuticals, and contrast agents.

9. The system of claim 1, wherein the pump is selected from the following:

a turbine pump, a peristaltic pump, a diaphragm pump, a screw pump, a syringe pump, and a centrifugal pump.

10. The system of claim 1, wherein the pump comprises a peristaltic pump arranged to contact at least a portion of the fluid delivery channel such that operation of the pump compresses the at least a portion of the fluid delivery channel and forces the fluid from the fluid source toward a dispensing element through the fluid delivery channel,

wherein the volume of the aliquot is affected by at least one dimensional property of the fluid delivery channel.

11. The system of claim 10, wherein the at least one dimensional property comprises an inner diameter.

12. The system of claim 10, wherein the at least one dimensional property comprises an outer diameter.

13. A method of dispensing a fluid, comprising:

providing a pump configured to force an aliquot of fluid from a fluid source into a fluid delivery channel;

receiving, by a processor, a source value of the property for the fluid source and a sample value of the property for the aliquot measured by at least one sensor;

determining, by the processor, a volume of the aliquot based on a comparison of the sample value and the source value; and

controlling, by the processor, operation of the pump to dispense a predetermined dose of the fluid based on a comparison of the sample volume with an expected volume.

14. The method of claim 13, further comprising determining, by the processor, a pump coefficient based on the comparison of the sample volume with the expected volume, the pump coefficient being configured to indicate a volume of fluid forced into the fluid delivery channel per unit.

15. The method of claim 14, wherein the pump coefficient comprises a volume-per-time coefficient.

16. The method of claim 14, wherein the pump coefficient comprises a volume-per-revolution coefficient.

17. The method of claim 14, wherein controlling operation of the pump further comprises controlling the pump using the pump coefficient.

18. The method of claim 14, wherein controlling operation of the pump further comprises adjusting the pump coefficient to correspond with dispensing the predetermined dose.

19. The method of claim 13, wherein the expected volume comprises a volume of the fluid forced by the pump under standard conditions.

20. The method of claim 13, wherein the pump is selected from the following:

a turbine pump, a peristaltic pump, a diaphragm pump, a screw pump, a syringe pump, and a centrifugal pump.