DELIVERY WIRE FOR OCCLUSIVE DEVICE DELIVERY SYSTEM

• US 20140249570A1
• Filed: 05/19/2014
• Published: 09/04/2014
• Est. Priority Date: 04/06/2009
• Status: Active Grant

• Current Assignee: Stryker European Operations Holdings, LLC (Stryker Corporation)
• Original Assignee: Stryker Corporation, Stryker Nv Operations Limited (Stryker Corporation)
• Inventors: Chen, Hancun, Dao, Jimmy, Murphy, Richard
• Granted Patent: US 9,504,475 B2
• Time in Patent Office: Days
• US Class Current: 606/200
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 2017/12063 electrolytically detachable
• CPC Class Codes: A61B 2017/12068 detachable by heat
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61M 2025/09133 having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque
• CPC Class Codes: A61M 2025/0915 having features for changing the stiffness

Abstract

A delivery wire assembly for delivery of an occlusive device to a location in a patient'"'"'s vasculature includes a delivery wire conduit having a proximal tubular portion connected to a distal coil portion, and a conduit lumen extending through the proximal tubular portion and the distal coil portion. The delivery wire assembly also includes a core wire disposed in the conduit lumen and having a distal end coupled to an occlusive device. The distal coil portion of the delivery wire assembly includes a plurality of zones and the plurality of zones decrease in stiffness distally along the length of the distal coil portion of the delivery wire assembly.

Claims

1. A delivery wire assembly for delivery of an occlusive device to a vascular implantation location, comprising:

a delivery wire conduit having a proximal tubular portion connected to a distal coil portion, and a conduit lumen extending through the respective proximal tubular portion and distal coil portion;

a core wire extending into in the conduit lumen, the core wire being permanently fixed to the delivery wire conduit so that the core wire and the delivery wire conduit are not longitudinally movable relative to each other; and

an occlusive device coupled to a distal end of the core wire,

wherein the distal coil portion comprises a proximal zone including one or more proximal zone windings formed from a proximal zone laminated coil wire having a proximal zone lamination thickness, and a distal zone including one or more distal zone windings formed from a distal zone laminated coil wire having a distal zone lamination thickness less than the proximal zone lamination thickness.

2. The delivery wire assembly of claim 1, the proximal zone having a proximal zone stiffness, and the distal zone having a distal zone stiffness that is less than the proximal zone stiffness.

3. The delivery wire assembly of claim 1, the one or more proximal zone windings having a proximal zone pitch, and the one or more distal zone windings having a distal zone pitch that is greater than the proximal zone pitch.

4. The delivery wire assembly of claim 3, wherein the distal zone pitch is in a range of 10% to 20%.

5. The delivery wire assembly of claim 1, wherein the proximal zone laminated coil wire has a proximal zone outer diameter, and the distal zone laminated coil wire has a distal zone outer diameter that is less than the proximal zone outer diameter.

6. The delivery wire assembly of claim 1, wherein the proximal zone laminated coil wire has a proximal zone tensile strength, and the distal zone laminated coil wire has a distal zone tensile strength this is less than the proximal zone tensile strength.

7. The delivery wire assembly of claim 1, wherein the proximal zone laminated coil wire has a proximal zone modulus of elasticity, and the distal zone laminated coil wire has a distal zone modulus of elasticity that is less than the proximal zone modulus of elasticity.

8. The delivery wire assembly of claim 1, wherein the proximal zone laminated coil wire has a circular cross-section and the distal zone laminated coil wire has an ellipsoid cross-section.

9. The delivery wire assembly of claim 1, wherein the distal coil portion further comprises a middle zone located between the respective proximal and distal zones, the middle zone including one or more middle zone windings formed from a middle zone laminated coil wire having a middle zone lamination thickness, wherein the middle zone lamination thickness is less than the proximal zone lamination thickness and greater than the distal zone lamination thickness.

10. The delivery wire assembly of claim 9, the proximal zone having a proximal zone stiffness, the middle zone having a middle zone stiffness that is less than the proximal zone stiffness, and the distal zone having a distal zone stiffness that is less than the middle zone stiffness.

11. The delivery wire assembly of claim 9, the one or more proximal zone windings having a proximal zone pitch, the one or more middle zone windings having a middle zone pitch that is greater than the proximal zone pitch, and the one or more distal zone windings having a distal zone pitch that is greater than the middle zone pitch.

12. The delivery wire assembly of claim 11, wherein the proximal zone pitch is about 0%, the middle zone pitch is in a range of 5% to 9%, and the distal zone pitch in a range of 10% to 20%.

13. The delivery wire assembly of claim 12, wherein the proximal zone pitch is about 0%, the middle zone pitch is about 5%, and the distal zone pitch is about 10%.

14. The delivery wire assembly of claim 9, wherein the proximal zone laminated coil wire has a proximal zone outer diameter, the middle zone laminated coil wire has a middle zone outer diameter that is less than the proximal zone outer diameter, and the distal zone laminated coil wire has a distal zone outer diameter that is less than the middle zone outer diameter.

15. The delivery wire assembly of claim 14, wherein the proximal zone outer diameter is about 0.00250 inches, the middle zone outer diameter is about 0.00225 inches, and the distal zone outer diameter is about 0.00200 inches.

16. The delivery wire assembly of claim 9, wherein the proximal zone laminated coil wire has a proximal zone tensile strength, the middle zone laminated coil wire has a middle zone tensile strength this is less than the proximal zone tensile strength, and the distal zone laminated coil wire has a distal zone tensile strength this is less than the middle zone tensile strength.

17. The delivery wire assembly of claim 16, wherein the proximal zone tensile strength is in a range of 300 ksi to 350 ksi, the middle zone tensile strength is in a range of 250 ksi to 299 ksi, and the distal zone tensile strength is in a range of 200 ksi to 249 ksi.

18. The delivery wire assembly of claim 9, wherein the proximal zone laminated coil wire has a proximal zone modulus of elasticity, the middle zone laminated coil wire has a middle zone modulus of elasticity that is less than the proximal zone modulus of elasticity, and the distal zone laminated coil wire has a distal zone modulus of elasticity that is less than the middle zone modulus of elasticity.

19. The delivery wire assembly of claim 9, wherein the proximal zone laminated coil wire has a circular cross-section, the middle zone laminated coil wire has an ellipsoid cross-section having a middle zone major axis, and the distal zone laminated coil wire has a distal zone ellipsoid cross-section having a distal zone major axis that is greater than the middle zone major axis.

20. An occlusive device delivery system, comprising:

a delivery catheter having a proximal end, a distal end, and a catheter lumen extending between the proximal and distal ends;

the delivery wire assembly, comprising

a delivery wire conduit having a proximal tubular portion connected to a distal coil portion, and a conduit lumen extending through the respective proximal tubular portion and distal coil portion,

a core wire extending into in the conduit lumen, the core wire being permanently fixed to the delivery wire conduit so that the core wire and the delivery wire conduit are not longitudinally movable relative to each other, and

an occlusive device coupled to a distal end of the core wire,

wherein the distal coil portion comprises a proximal zone including one or more proximal zone windings formed from a proximal zone laminated coil wire having a proximal zone lamination thickness, and a distal zone including one or more distal zone windings formed from a distal zone laminated coil wire having a distal zone lamination thickness less than the proximal zone lamination thickness; and

a power supply electrically connected to the core wire.