Transapical Mitral Valve Replacement

• US 20140249621A1
• Filed: 02/26/2014
• Published: 09/04/2014
• Est. Priority Date: 03/01/2013
• Status: Active Grant

• Current Assignee: St. Jude Medical Cardiology Division Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: St. Jude Medical Cardiology Division Incorporated (Abbott Laboratories Incorporated)
• Inventors: Eidenschink, Tracee
• Granted Patent: US 9,844,435 B2
• Time in Patent Office: Days
• US Class Current: 623/2.11
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2439 Expansion controlled by filaments
• CPC Class Codes: A61F 2/2457 Chordae tendineae prostheses
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2220/0033 made by longitudinally pushing a protrusion into a complementary-shaped recess, e.g. held by friction fit
• CPC Class Codes: A61F 2230/0091 helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section

Abstract

A prosthetic heart valve includes a collapsible and expandable stent having an outflow end and an inflow end, a plurality of commissure features attached to the stent, a plurality of anchoring features disposed on legs of the stent, the plurality of anchoring features being coupleable to a delivery device for repositioning, and a valve assembly disposed within the stent. The anchoring features may be configured to attach to heart tissue to help secure the prosthetic heart valve in an operating position.

Claims

1. A prosthetic heart valve, comprising:

a collapsible and expandable stent having an outflow end and an inflow end, the outflow end including a plurality of legs movable between a substantially straight configuration and a relaxed configuration capable of grasping heart tissue;

a plurality of commissure features disposed on the stent;

a plurality of anchoring features disposed on respective ones of the plurality of legs, the plurality of anchoring features being coupleable to a delivery device; and

a collapsible and expandable valve assembly disposed within the stent.

2. The prosthetic heart valve of claim 1, wherein each of the legs is biased to move to a curled configuration in a relaxed configuration.

3. The prosthetic heart valve of claim 2, wherein each of the legs is configured to curl about the chordae tendinea in the curled configuration.

4. The prosthetic heart valve of claim 2, wherein the curled configuration is a helical configuration, the legs being biased to move to the helical configuration in the relaxed configuration.

5. The prosthetic heart valve of claim 1, wherein the plurality of anchoring features includes at least one C-shaped barb.

6. The prosthetic heart valve of claim 1, wherein the outflow end of the stent has an expanded circumference, and the inflow end of the stent has a flared portion, the flared portion having an expanded circumference that is larger than the expanded circumference of the outflow end of the stent.

7. The prosthetic heart valve of claim 1, wherein the heart valve is a mitral valve.

8. The prosthetic heart valve of claim 1, wherein the valve assembly includes a plurality of leaflets.

9. The prosthetic heart valve of claim 8, further comprising sutures connecting the plurality of leaflets to the plurality of commissure features.

10. A catheter for delivering a prosthetic heart valve to a deployment site in a patient, the catheter comprising:

an outer sheath;

a plurality of wires disposed within the outer sheath, each of the plurality of wires terminating in at least one coupler operable to connect to a portion of the prosthetic heart valve; and

a plurality of sleeves, each one of the plurality of sleeves being disposed about one of the plurality of wires.

11. The catheter of claim 10, wherein the plurality of wires are formed from a shape-memory material.

12. The catheter of claim 10, wherein the at least one coupler includes a hook.

13. The catheter of claim 10, wherein the plurality of wires are formed from a suture material.

14. The catheter of claim 10, wherein the at least one coupler includes a suture loop.

15. The catheter of claim 10, wherein each of the plurality of sleeves is translatable relative to the plurality of wires.

16. The catheter of claim 10, further comprising an inner tube for accepting the plurality of wires.

17. The catheter of claim 10, wherein each of the at least one coupler is configured to mate with a plurality of terminal legs of the prosthetic heart valve.

18. A method of deploying a prosthetic heart valve at a target site, the prosthetic heart valve including a collapsible and expandable stent having an outflow end and an inflow end, and a collapsible and expandable valve assembly disposed within the stent, the method comprising:

introducing a delivery device to the target site, the delivery device including an outer sheath, the prosthetic heart valve being disposed within the outer sheath, a plurality of wires disposed within the outer sheath, each of the plurality of wires terminating in a coupler connected to the heart valve, and a plurality of sleeves, each one of the plurality of sleeves being disposed about one of the plurality of wires;

withdrawing the sheath a first distance to partially deploy the prosthetic heart valve at the target site such that the valve assembly is partially deployed at the first distance and can function as intended while the outflow end of the stent is coupled to the plurality of wires; and

pulling at least one of the plurality of wires to reposition the heart valve.

19. The method of claim 18, further comprising withdrawing the plurality of sleeves to expose the plurality of wires.

20. The method of claim 18, further comprising decoupling the couplers from the heart valve.

21. The method of claim 20, wherein the plurality of wires includes a suture material and the decoupling step includes cutting the suture material.

22. The method of claim 20, wherein the coupler includes a hook and the decoupling step includes detaching the hook from the heart valve.