DIALYSIS TREATMENT DEVICES FOR REMOVING UREA
First Claim
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1. A method for removing urea from a dialysis fluid, the method comprising:
- circulating the dialysis fluid in a fluid circuit that includes a dialysis apparatus having cartridge comprising
1) a first filter comprising a filtration membrane,
2) a urea removal unit comprising urease and in fluid communication with a filtrate stream of the first filter,
3) a second filter comprising an ion rejection membrane and receiving at least one of the filtrate stream of the first filter and a filtrate stream of the urea removal unit, and
4) a flow restrictor positioned between the first filter and the second filter;
removing urea from the dialysis fluid with the cartridge; and
recirculating a filtrate stream of the second filter back to patient.
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Abstract
Dialysis treatment devices and methods for removing urea from dialysis waste streams are provided. In a general embodiment, the present disclosure provides a dialysis treatment device including: 1) a first filter having a filtration membrane, 2) a urea removal unit having urease and in fluid communication with the first filter, and 3) a second filter having an ion rejection membrane and in fluid communication with the first filter and the urea removal unit.
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Citations
20 Claims
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1. A method for removing urea from a dialysis fluid, the method comprising:
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circulating the dialysis fluid in a fluid circuit that includes a dialysis apparatus having cartridge comprising
1) a first filter comprising a filtration membrane,
2) a urea removal unit comprising urease and in fluid communication with a filtrate stream of the first filter,
3) a second filter comprising an ion rejection membrane and receiving at least one of the filtrate stream of the first filter and a filtrate stream of the urea removal unit, and
4) a flow restrictor positioned between the first filter and the second filter;removing urea from the dialysis fluid with the cartridge; and recirculating a filtrate stream of the second filter back to patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method for removing urea from a dialysis fluid, the method comprising:
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circulating the dialysis fluid in a fluid circuit that includes a dialysis apparatus having cartridge comprising
1) a filter comprising an adsorption layer, a filtration membrane, and an ion exchange sorbent, and
2) a urea removal unit in fluid communication with a filtrate stream of the filter, the urea removal unit comprising a urease layer, an ammonia sorbent layer and an ion rejection membrane;removing urea from the dialysis fluid with the cartridge; and recirculating filtrate streams of the filter and the urea removal unit back to the patient. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification