USE OF WHEY PROTEIN MICELLES FOR IMPROVING INSULIN PROFILE IN DIABETIC PATIENTS

• US 20140255544A1
• Filed: 10/19/2012
• Published: 09/11/2014
• Est. Priority Date: 10/21/2011
• Status: Active Application

• Current Assignee: Societe des Produits Nestle SA (Nestle SA)
• Original Assignee: Nestec SA (Nestle SA)
• Inventors: Pouteau, Etienne, Bovetto, Lionel Jean Rene, Mace, Catherine
• Application Number:
  US14/353,188
• Publication Number:
  US 20140255544A1
• Time in Patent Office: Days
• US Class Current: 426/2
• CPC Class Codes: A23C 21/00 Whey; Whey preparations concentration, evaporation or drying A23C1/00; preservation of milk or milk preparations A23C3/00; milk preparations, milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment A23C9/14
• CPC Class Codes: A23J 1/205 from whey, e.g. lactalbumine
• CPC Class Codes: A23K 20/147 Polymeric derivatives, e.g. peptides or proteins
• CPC Class Codes: A23L 2/52 Adding ingredients adding preservatives A23L2/44
• CPC Class Codes: A23L 2/66 Proteins
• CPC Class Codes: A23L 33/19 Dairy proteins
• CPC Class Codes: A23L 33/30 Dietetic or nutritional methods, e.g. for losing weight A23L33/10 takes precedence
• CPC Class Codes: A23L 33/40 Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2200/00 Function of food ingredients
• CPC Class Codes: A23V 2200/332 Promoters of weight control and weight loss
• CPC Class Codes: A23V 2250/54252 Whey protein
• CPC Class Codes: A61K 35/20 Milk; Whey; Colostrum
• CPC Class Codes: A61P 3/10 for hyperglycaemia, e.g. antidiabetics

Abstract

The present invention relates to whey protein micelles for use in the treatment and/or prevention of a disorder linked to an increase in plasma postprandial insulin and/or plasma postprandial glucagon concentration in a subject. The invention relates also to a non-therapeutic use of whey protein micelles to decrease plasma postprandial insulin and/or glucagon concentration in healthy subjects.

Claims

1. A method for use in the treatment and/or prevention of a disorder linked to an increase in plasma postprandial insulin and/or plasma postprandial glucagon concentration in a subject in need of same comprising administering to the subject whey protein micelles.

2. The method for use according to claim 1, wherein the disorder is selected from the group consisting of insulin resistance, metabolic syndrome, glucose intolerance and diabetes type-2.

3. The method according to claim 1, wherein the subject is a diabetic or pre-diabetic patient.

4. The method according to claim 1, wherein the subject is a human being or an animal, cat or a dog.

5. The method according to claim 1, wherein the whey protein micelles are provided to a subject in a daily dose of at least 20 g dry weight.

6. The method according to claim 1, wherein the whey protein micelles are provided as part or at the end of a regular meal.

7. The method according to claim 1, wherein the whey protein micelles are provided in the a form selected from the group consisting of a liquid drink, a shake drink and a liquid meal replacement.

8. The method according to claim 1, wherein the whey protein micelles are provided in the form of a solid food product.

9. A non-therapeutic method to decrease plasma postprandial insulin and/or plasma postprandial glucagon concentration in a subject in need of same comprising administering a whey protein micelles composition.

10. The non-therapeutic method according to claim 9, wherein the subject is a human being or an animal.

11. A liquid meal replacement comprising whey protein micelles.

12. The meal replacement of claim 11, wherein the whey protein micelles are present in an amount of at least 15 wt %.

13. The meal replacement of claim 11 for use in enteral nutrition.