SWEAT ANALYTE TESTING COMPONENTS AND METHODS

• US 20140257064A1
• Filed: 03/11/2014
• Published: 09/11/2014
• Est. Priority Date: 03/11/2013
• Status: Abandoned Application

• Current Assignee: Birchwood Laboratories LLC
• Original Assignee: Birchwood Laboratories Incorporated
• Inventors: Einck, Cydney A., Erickson, Nathan R., Hepp, Dennis, Messer, Gary A.
• Application Number:
  US14/204,842
• Publication Number:
  US 20140257064A1
• Time in Patent Office: Days
• US Class Current: 600/346
• CPC Class Codes: A61B 2503/045 Newborns, e.g. premature baby monitoring
• CPC Class Codes: A61B 2560/0462 Apparatus with built-in sensors
• CPC Class Codes: A61B 2562/0295 Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157 disposable multilayered or laminated electrodes G01N27/307; details of handling chemical test elements G01N33/4875
• CPC Class Codes: A61B 2562/08 Sensors provided with means for identification, e.g. barcodes or memory chips
• CPC Class Codes: A61B 5/14521 using means for promoting sweat production, e.g. heating the skin measuring sweat secretion A61B5/4266
• CPC Class Codes: A61B 5/4266 sweat secretion
• CPC Class Codes: A61N 1/0412 Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
• CPC Class Codes: A61N 1/0428 Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs

Abstract

Embodiments of the invention include adhesive electrode sets and related methods. In an embodiment, the invention includes an adhesive electrode set. The adhesive electrode set can include a first pad, a first electrode, a first electrical contact, a first conductive lead, a second pad, a second electrode, a second electrical contact, a second conductive lead, a flexible strip, and an adhesive material. The flexible strip can include a fold. The flexible strip can be configured to allow the distance between the first pad and the second pad to increase through flexion of the flexible strip. In an embodiment, the invention includes an analyte receiving test patch. The analyte receiving test patch can include a skin contact layer, a wick, an absorbent layer, a barrier film layer, and an adhesive frame. Other embodiments are also included herein.

Claims

1. An adhesive electrode set comprising:

a first pad, the pad comprising a flexible substrate and defining a first aperture;

a first electrode aligned with the first aperture;

a first electrical contact;

a first conductive lead providing electrical communication between the first electrode and the first electrical contact;

a second pad, the pad comprising a flexible substrate and defining a second aperture;

a second electrode aligned with the second aperture;

a second electrical contact;

a second conductive lead providing electrical communication between the second electrode and the second electrical contact;

a flexible strip connecting the first pad and the second pad, the first and second conductive leads attached to the flexible strip, the flexible strip comprising a fold and configured to allow the distance between the first pad and the second pad increase through unfolding of the fold in the flexible strip; and

an adhesive material disposed under the first pad and the second pad.

2. The adhesive electrode set of claim 1, wherein the first electrical contact and the second electrical contact are disposed together on top of the flexible strip.

3. The adhesive electrode set of claim 1, wherein the first electrical contact and the second electrical contact are disposed together on top of one of the first pad or the second pad.

4. The adhesive electrode set of claim 1, wherein the first conductive lead is disposed over the second conductive lead, but the first conductive lead is electrically isolated from the second conductive lead.

5. The adhesive electrode set of claim 1, wherein the first electrical contact is not disposed over the first electrode.

6. The adhesive electrode set of claim 1, wherein the second electrical contact is not disposed over the second electrode.

7. The adhesive electrode set of claim 1, the first pad comprising a polyurethane foam.

8. The adhesive electrode set of claim 1, the second pad comprising a polyurethane foam.

9. The adhesive electrode set of claim 1, the adhesive electrode set comprising a first hydrogel.

10. The adhesive electrode set of claim 1, the sweat inducing agent comprising pilocarpine nitrate.

11. The adhesive electrode set of claim 1, the adhesive electrode set comprising a second hydrogel.

12. The adhesive electrode set of claim 11, the second hydrogel comprising a salt.

13. The adhesive electrode set of claim 12, the salt comprising potassium sulfate.

14. The adhesive electrode set of claim 1, the first conductive lead and the second conductive lead comprising a conductive ink.

15. The adhesive electrode set of claim 1, the fold comprising a Z-bend fold.

16. The adhesive electrode set of claim 1, wherein the distance between the first pad and the second pad can vary between 0 mm and 200 mm through unfolding of the fold.

17. The adhesive electrode set of claim 1, the flexible strip comprising a polyester backer.

18. The adhesive electrode set of claim 1, the adhesive electrode set comprising a second adhesive material.

19. A kit comprising:

an adhesive electrode set comprising

a first pad, the pad comprising a flexible substrate and defining a first aperture;

a first electrode aligned with the first aperture;

a first electrical contact;

a first conductive lead providing electrical communication between the first electrode and the first electrical contact;

a second pad, the pad comprising a flexible substrate and defining a second aperture;

a second electrode aligned with the second aperture;

a second electrical contact;

a second conductive lead providing electrical communication between the second electrode and the second electrical contact;

a flexible strip connecting the first pad and the second pad, the first and second conductive leads attached to the flexible strip, the flexible strip comprising a fold and configured to allow the distance between the first pad and the second pad increase through unfolding of the fold in the flexible strip; and

an adhesive material disposed under the first pad and the second pad; and

a chloride test patch comprising

a skin contact layer comprising an aperture;

a wick configured to engage the aperture in the skin contact layer;

an absorbent layer disposed over the skin contact layer;

a barrier film layer disposed over the absorbent layer, the barrier film comprising a fill line imprinted thereon; and

an adhesive frame disposed over the barrier film layer.

20. The kit of claim 19, the absorbent layer comprising silver chromate.

21. The kit of claim 19, the absorbent layer comprising phenol red.

22. The kit of claim 19, wherein the barrier film configured to separate from the skin contact laminate and components after sweat absorption to stop liquid migration.

23. The kit of claim 19, the analyte receiving test patch comprising barcode panel.