PERCUTANEOUS MITRAL VALVE REPLACEMENT AND SEALING
First Claim
1. Apparatus for use with a prosthetic valve for implantation at a native valve of a subject, the native valve including at least one native leaflet, the apparatus comprising:
- a prosthetic, valve support, comprising;
an upstream support portion, being configured to be placed against an upstream side of the native valve, and having an inner perimeter that defines an opening that is configured to receive the prosthetic valve, andat least one clip;
comprising at least two clip arms and a clip-controller interface, the clip-controller interface being coupled to at least one of the clip arms, andbeing configured to be coupled to a native leaflet of the native valve; and
at least one clip controller, reversibly couplable to the clip-controller interface, and configured to facilitate opening and closing of the clip.
3 Assignments
0 Petitions
Accused Products
Abstract
Apparatus is provided for use with a prosthetic valve for implantation at a native valve of a subject, the native valve including at least one native leaflet, the apparatus including (1) a prosthetic valve support, including (a) an upstream support portion, being configured to be placed against an upstream side of the native valve, and having an inner perimeter that defines an opening that is configured to receive the prosthetic valve, and (b) at least one clip (i) comprising at least two clip arms and a clip-controller interface, the clip-controller interface being coupled to at least one of the clip arms, and (ii) being configured to be coupled to a native leaflet of the native valve; and (2) at least one clip controller, reversibly couplable to the clip-controller interface, and configured to facilitate opening and closing of the clip. Other embodiments are also described.
230 Citations
58 Claims
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1. Apparatus for use with a prosthetic valve for implantation at a native valve of a subject, the native valve including at least one native leaflet, the apparatus comprising:
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a prosthetic, valve support, comprising; an upstream support portion, being configured to be placed against an upstream side of the native valve, and having an inner perimeter that defines an opening that is configured to receive the prosthetic valve, and at least one clip; comprising at least two clip arms and a clip-controller interface, the clip-controller interface being coupled to at least one of the clip arms, and being configured to be coupled to a native leaflet of the native valve; and at least one clip controller, reversibly couplable to the clip-controller interface, and configured to facilitate opening and closing of the clip. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 41, 42)
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16-40. -40. (canceled)
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43. Apparatus for use at a native valve of a heart of a subject, the native valve including one or more leaflets, the apparatus comprising:
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an upstream support portion; having a delivery state in which the upstream support portion is dimensioned to he transluminally advanced to the heart, and having an expanded state in which the upstream support portion is annular and configured to be disposed against an annulus of the native valve; at least two connectors; at least two clips, each of the clips; coupled to the upstream support portion via a respective one of the connectors, comprising at least two clip arms and a clip-controller interface coupled to at least one of the clip arms, and configured to be coupled to one of the leaflets by clamping the leaflet between the clip arms; and a clip controller, reversibly couplable to the clip-controller interface of at least one of the clips, and configured to facilitate opening and closing of the at least one of the clips. - View Dependent Claims (44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56)
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57. A method, comprising:
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transluminally advancing an upstream support portion, in a delivery state thereof, to a heart of a subject; placing the upstream support portion, in an annular expanded state thereof, against an annulus of a native valve of the heart; and using at least one clip controller; coupling a first clip to a first leaflet of the native valve, the at least one clip controller being reversibly coupled to a clip-controller interface of the first clip; and coupling a second clip to a second leaflet of the native valve, the at least one clip controller being reversibly coupled to a clip-controller interface of the second clip, each of the clips being coupled to the upstream support portion via a respective flexible connector. - View Dependent Claims (58)
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Specification