Method and System for Providing Contextual Based Medication Dosage Determination

• US 20140258190A1
• Filed: 05/16/2014
• Published: 09/11/2014
• Est. Priority Date: 02/18/2007
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories)
• Inventors: Doniger, Kenneth J., Sloan, Mark Kent
• Granted Patent: US 12,040,067 B2
• Time in Patent Office: Days
• US Class Current: 706/12
• CPC Class Codes: A61P 3/10 for hyperglycaemia, e.g. antidiabetics
• CPC Class Codes: G06F 16/13 File access structures, e.g. distributed indices arrangements of input from, or output to, record carriers G06F3/06
• CPC Class Codes: G06F 16/245 Query processing
• CPC Class Codes: G06F 16/636 by using biological or physiological data
• CPC Class Codes: G06F 16/972 Access to data in other repository systems, e.g. legacy data or dynamic Web page generation
• CPC Class Codes: G06N 20/00 Machine learning
• CPC Class Codes: G06N 5/04 Inference or reasoning models
• CPC Class Codes: G16H 20/17 delivered via infusion or injection

Abstract

Methods and devices for statistical determination of medication dosage level such as bolus amount based on contextual information are provided.

Claims

1. A method, comprising:

assigning a time based weighted value to one or more previously determined medication dosage levels in a decreasing weighted order based on time such that a more recent medication dosage level is assigned a heavier time based weighted value than an older medication dosage level; and

generating a recommended medication dosage level based on the one or more previously determined medication dosage levels based on one or more parameters associated with a physiological condition and the time based weighted value assigned to the one or more previously determined medication dosage levels.

2. The method of claim 1, further including outputting the recommended medication dosage level including effects of at least one of the one or more previously determined medication dosage levels on the physiological condition on a display device.

3. The method of claim 1, further including updating a database with the recommended medication dosage level when the recommended medication dosage level is administered.

4. The method of claim 3, wherein updating the database includes:

receiving confirmation of administration of a medication amount associated with the recommended medication dosage level;

associating the recommended medication dosage level with the one or more parameters; and

storing the recommended medication dosage level.

5. The method of claim 3, wherein the database includes a plurality of previously determined medication dosage levels and one or more associated parameters for each of the plurality of the previously determined medication dosage levels.

6. The method of claim 5, wherein one or more of the plurality of the previously determined medication dosage levels stored in the database includes administered medication dosage information.

7. The method of claim 1, further including performing statistical analysis based on the one or more parameters.

8. The method of claim 7, wherein the statistical analysis includes one or more of mean deviation analysis, standard deviation analysis, estimation analysis, forecasting analysis, correlation of the one or more parameters, modeling of one or more relationships among the one or more parameters, regression analysis, time series analysis, autoregressive modeling, integrated modeling, moving average modeling, data mining, or probability analysis.

9. The method of claim 1, wherein the one or more parameters includes one or more of a current glucose level, an insulin sensitivity, a target glucose level, a past glucose level, glucose trend information, an amount of carbohydrate to be ingested, insulin on board information, exercise information, time of day information, or one or more combinations thereof.

10. The method of claim 1, wherein after a predetermined time period, at least one of the one or more previously determined medication dosage levels is assigned a second time based weighted value that results in the one or more previously determined medication dosage levels to no longer impact the recommended medication dosage level.

11. An apparatus, comprising:

one or more processing units; and

a memory for storing instructions which, when executed by the one or more processing units, causes the one or more processing units to assign a time based weighted value to one or more previously determined medication dosage levels in a decreasing weighted order based on time such that a more recent medication dosage level is assigned a heavier time based weighted value than an older medication dosage level, and to generate a recommended medication dosage level based on the one or more previously determined medication dosage levels based on one or more parameters associated with a physiological condition and the time based weighted value assigned to the one or more previously determined medication dosage levels.

12. The apparatus of claim 11, further including a display device for outputting the recommended medication dosage level including effects of at least one of the one or more previously determined medication dosage levels on the physiological condition.

13. The apparatus of claim 11, wherein the memory for storing instructions which, when executed by the one or more processing units, causes the one or more processing units to update a database with the recommended medication dosage level when the recommended medication dosage level is administered.

14. The apparatus of claim 13, wherein the memory for storing instructions which, when executed by the one or more processing units, causes the one or more processing units to update the database including receiving confirmation of administration of a medication amount associated with the recommended medication dosage level, associating the recommended medication dosage level with the one or more parameters, storing the recommended medication dosage level.

15. The apparatus of claim 13, wherein the database includes a plurality of previously determined medication dosage levels and one or more associated parameters for each of the plurality of the previously determined medication dosage levels.

16. The apparatus of claim 11, wherein the memory for storing instructions which, when executed by the one or more processing units, causes the one or more processing units to perform statistical analysis based on the one or more parameters.

17. The apparatus of claim 16, wherein the statistical analysis includes one or more of mean deviation analysis, standard deviation analysis, estimation analysis, forecasting analysis, correlation of the one or more parameters, modeling of one or more relationships among the one or more parameters, regression analysis, time series analysis, autoregressive modeling, integrated modeling, moving average modeling, data mining, or probability analysis.

18. The apparatus of claim 11, wherein the one or more parameters includes one or more of a current glucose level, an insulin sensitivity, a target glucose level, a past glucose level, glucose trend information, an amount of carbohydrate to be ingested, insulin on board information, exercise information, time of day information, or one or more combinations thereof.

19. The apparatus of claim 11, wherein the one or more processing units and the memory are operatively coupled to a medical device.

20. The apparatus of claim 11, wherein after a predetermined time period the memory for storing instructions which, when executed by the one or more processing units, causes the one or more processing units to assign a second time based weighted value that results in at least one of the one or more previously determined medication dosage levels to no longer impact the recommended medication dosage level.