DEVICES CONTAINING A CHEMICAL DENERVATION AGENT AND METHODS FOR TREATING CHRONIC BACK PAIN USING CHEMICAL DENERVATION
First Claim
1. A device for treating chronic back pain in a patient in need of such treatment, the device configured to deliver a chemical denervation agent to an effective treatment zone comprising a nerve at a target region of the spine so as to chemically ablate the nerve.
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Accused Products
Abstract
Effective devices and methods using a chemical denervation agent are provided for treating chronic back pain. The devices and methods comprise a chemical denervation agent to degrade or to shrink at least a portion of a nerve associated with back pain e.g. basivertebral nerve of the lumbar. In some embodiments, the methods and devices are configured to immediately release an effective amount of the chemical denervation agent within 24 hours and provide sustained release of the chemical denervation agent or other therapeutic agent over a period of up to one year to treat chronic back pain.
63 Citations
20 Claims
- 1. A device for treating chronic back pain in a patient in need of such treatment, the device configured to deliver a chemical denervation agent to an effective treatment zone comprising a nerve at a target region of the spine so as to chemically ablate the nerve.
- 15. A device for treating chronic back pain in a patient in need of such treatment, the device being implantable in or near an the basivertebral nerve of the patient, the device comprising a chemical denervation agent and having an immediate release component configured to release an effective amount of the chemical denervation agent within 24 hours to ablate at least a portion of the basivertebral nerve of the patient.
- 17. A method for treating chronic back pain in a patient in need of such treatment, the method comprising the steps of positioning a delivery device for delivery of a chemical denervation agent in or near an effective treatment zone containing a basivertebral nerve for administering a chemical denervation agent to chemically ablate at least a portion of the basivertebral nerve so as to treat chronic back pain of the patient.
Specification