Bioerodible Silicon-Based Delivery Vehicles for Delivery of Therapeutic Agents
First Claim
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1. A sustained release drug delivery composition comprising:
- a) a porous carrier material comprising a silicon-based compound; and
b) at least one therapeutic agent associated with the carrier material, wherein the at least one therapeutic agent includes adrenocorticotropic hormone (ACTH) or an analog thereof.
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Abstract
This invention discloses bioerodible delivery compositions for delivering peptide therapeutic agents. The delivery compositions comprise a porous silicon-based carrier material loaded with the therapeutic agent. The delivery compositions may be used in vitro or in vivo to deliver the therapeutic agent, preferably in a controlled fashion over an intended period of time such as over multiple days, weeks or months. The delivery compositions may be used for treating or preventing conditions of a patient such as chronic diseases.
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12 Claims
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1. A sustained release drug delivery composition comprising:
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a) a porous carrier material comprising a silicon-based compound; and b) at least one therapeutic agent associated with the carrier material, wherein the at least one therapeutic agent includes adrenocorticotropic hormone (ACTH) or an analog thereof. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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Specification