METHOD AND SYSTEM FOR DERIVING EFFECTIVENESS OF MEDICAL TREATMENT OF A PATIENT

• US 20140275827A1
• Filed: 05/15/2013
• Published: 09/18/2014
• Est. Priority Date: 03/14/2013
• Status: Abandoned Application

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Inventors: Shkurovich, Sergio, Gill, Amreeta, MacBroom, Tyler
• Application Number:
  US13/895,083
• Publication Number:
  US 20140275827A1
• Time in Patent Office: Days
• US Class Current: 600/301
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2018/00434 Neural system
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/0024 for multiple sensor units attached to the patient, e.g. using a body or personal area network
• CPC Class Codes: A61B 5/4848 Monitoring or testing the effects of treatment, e.g. of medication
• CPC Class Codes: A61B 5/746 Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms alarms per se G08B
• CPC Class Codes: A61N 1/37235 Aspects of the external programmer
• CPC Class Codes: G16H 40/67 for remote operation

Abstract

A method and system for deriving effectiveness of medical treatment of a patient are provided that include collecting patient state (PS) data from at least one of an implantable medical device (IMD) or an external medical device (EMD) over a collection interval. The collected PS data relates to a physiologic characteristic (PC) of the patient. The PS data is transferred to a database that is remote from the patient to form a patient state data (PSD) history. The patient undergoes a pivotal medical event (PME) during the collection interval. The PS data within the PSD history is analyzed before and after the PME to propose a treatment therapy (TT). Following delivery of the TT, the collecting and transferring operations are repeated to obtain post-treatment PS data and form a post-treatment PSD history. An effectiveness indicator (EI) of the TT is derived based on at least the post-treatment PSD history.

Claims

1. A method for deriving effectiveness of medical treatment of a patient, the method comprising:

collecting patient state (PS) data from at least one of an implantable medical device (IMD) or an external medical device (EMD) over a collection interval, the at least one IMD or EMD configured to collect the PS data in relation to a physiologic characteristic (PC) of the patient;

transferring the PS data to a database that is remote from the patient to form a patient state data (PSD) history, wherein the patient undergoes a pivotal medical event (PME) during the collection interval;

analyzing the PS data within the PSD history before and after the PME to propose a treatment therapy (TT);

following delivery of the TT, repeating the collecting and transferring operations to obtain post-treatment PS data and form a post-treatment PSD history; and

deriving an effectiveness indicator (EI) of the TT based on at least the post-treatment PSD history.

2. The method of claim 1, further comprising adjusting the TT based on the post-treatment PSD history.

3. The method of claim 2, wherein adjusting of the TT constitutes a prescription change or an acute intervention.

4. The method of claim 2, wherein the adjusting of the TT constitutes changing an output the at least one IMD or EMD.

5. The method of claim 1, wherein the deriving the effectiveness of the TT comprises comparing PS data that was collected from at least two different types of IMD or EMD before and after the PME.

6. The method of claim 1, wherein the collecting includes collecting first PS data from a first IMD or EMD and collecting second PS data from a second IMD or EMD.

7. The method of claim 1, wherein the PME represents at least one of a clinical event, an acute intervention, or a prescription change.

8. The method of claim 7, wherein the acute intervention comprises an ablation, implantation of an implantable cardioverter-defibrillator (ICD) device, left atrial appendage (LAA) closure, cardiac resynchronization therapy (CRT), spinal cord stimulation (SCS) therapy, renal denervation, or deep brain stimulation (DBS) therapy.

9. The method of claim 7 wherein the clinical event comprises at least one of a heart attack, a stroke, or detection of atrial fibrillation (AF), heart failure, or hypertension.

10. A method for deriving effectiveness of medical treatment of a patient, the method comprising:

collecting first patient state (PS) data from a first implantable medical device (IMD) over a collection interval, the first IMD configured to collect the first PS data in relation to a first physiologic characteristic (PC) of the patient;

collecting second PS data from a second IMD, the second IMD configured to collect the second PS data in relation to a second PC of the patient, the first PC differing from the second PC;

transferring the first and second PS data to a database that is remote from the patient to form a patient state data (PSD) history, wherein the patient undergoes a treatment therapy (TT) during the collection interval;

deriving an effectiveness indicator (EI) of the TT, by an assessment module, based on the first and second PS data collected before and after the TT.

11. The method of claim 10, further comprising proposing, by the assessment module, a potential prescription change to a user based on the assessment of the effectiveness.

12. The method of claim 10, further comprising changing at least one of a sensing, programmed parameters, or an output of the first IMD based on the second PS data from the second IMD.

13. The method of claim 10, further comprising integrating the first and second PS data where the first and second PS data relate to at least one of i) different first and second diseases or ii) first and second stages of progression of a single disease.

14. The method of claim 10, further comprising coordinating functional operation of the first IMD and the second IMD based on the EI and the first and second PS data.

15. The method of claim 10, wherein the first IMD and the second IMD are configured to treat different first and second diseases, respectively, the method further comprising setting, at the assessment module, operating parameters of the first IMD and operating parameters of the second IMD both based at least in part on the first PS data and the EI.

16. The method of claim 10, wherein the first IMD represents one of an ICD, pacemaker, spinal cord stimulation device, pressure sensor, or brain stimulator.

17. A system for deriving effectiveness of medical treatment of a patient, comprising:

at least one of an implantable medical device (IMD) or an external medical device (EMD) for collecting patient state (PS) data from over a collection interval, the at least one IMD or EMD configured to collect the PS data in relation to a physiologic characteristic (PC) of the patient;

a database configured to receive the PS data to form a patient state data (PSD) history, the database being remote from the patient, wherein the patient undergoes a pivotal medical event (PME) during the collection interval;

an analysis module configured to analyze the PS data within the PSD history before and after the PME to propose a treatment therapy (TT);

following delivery of the TT, the IMD or EMD and database repeating the collecting and receiving operations to obtain post-treatment PS data and a post-treatment PSD history; and

an assessment module configured to derive an effectiveness indicator (EI) of the TT based on at least the post-treatment PSD history.

18. The system of claim 17, further comprising a TT control module configured to adjust the treatment therapy based on the post-treatment PSD history.

19. A system for deriving effectiveness of medical treatment of a patient, the system comprising:

a first implantable medical device (IMD) configured to collect first patient state (PS) data over a collection interval, the first IMD configured to collect the first PS data in relation to a first physiologic characteristic (PC) of the patient;

a second IMD configured to collect second PS data in relation to a second PC of the patient, the first PC differing from the second PC;

a database located remote from the patient, the database configured to receive the first and second PS data to form a patient state data (PSD) history, wherein the patient undergoes a treatment therapy (TT) during the collection interval; and

an assessment module configured to derive an effectiveness indicator (EI) of the TT based on the first and second PS data collected before and after the TT.

20. The system of claim 19, wherein the assessment module is configured to propose a potential prescription change to a user based on the assessment of the effectiveness of the TT.