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ANALYTE SENSOR APPARATUSES COMPRISING MULTIPLE IMPLANTABLE SENSOR ELEMENTS AND METHODS FOR MAKING AND USING THEM

  • US 20140275899A1
  • Filed: 04/08/2014
  • Published: 09/18/2014
  • Est. Priority Date: 07/31/2008
  • Status: Active Grant
First Claim
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1. An apparatus for monitoring an analyte in a patient, the apparatus comprising:

  • a base adapted to secure the apparatus to the patient;

    a first piercing member coupled to and extending from the base;

    a first electrochemical sensor operatively coupled to the first piercing member, wherein the first electrochemical sensor comprises a plurality of working, counter and reference electrodes that are grouped together as a unit and positionally distributed in a repeating pattern of units;

    a second piercing member coupled to and extending from the base;

    a second electrochemical sensor operatively coupled to the second piercing member, wherein the second electrochemical sensor comprises a plurality of working, counter and reference electrodes that are grouped together as a unit and positionally distributed in a repeating pattern of units; and

    wherein;

    at least one physiological characteristic monitored by the first or the second electrochemical sensor comprises a concentration of a naturally occurring analyte in the patient;

    the first and second piercing members are disposed on the base in a configuration selected so that the first piercing member disposes the first electrochemical sensor in a first tissue compartment of the patient and the second piercing member disposes the second electrochemical sensor in a second tissue compartment of the patient; and

    the first and second piercing members are disposed on the base in a configuration selected to avoid a physiological response that can result from implantation of the first electrochemical sensor from altering a sensor signal generated by the second electrochemical sensor.

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