CARDIAC SIGNAL VECTOR SELECTION WITH MONOPHASIC AND BIPHASIC SHAPE CONSIDERATION

• US 20140275917A1
• Filed: 03/11/2014
• Published: 09/18/2014
• Est. Priority Date: 03/12/2013
• Status: Active Grant

• Current Assignee: Cameron Incorporated (Schlumberger NV)
• Original Assignee: Cameron Incorporated (Schlumberger NV)
• Inventors: Allavatam, Venugopal, Sanghera, Rick, Schroeder, Mark R.
• Granted Patent: US 9,579,065 B2
• Time in Patent Office: Days
• US Class Current: 600/374
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/341 Vectorcardiography [VCG]
• CPC Class Codes: A61B 5/7221 Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence
• CPC Class Codes: A61N 1/3702 Physiological parameters A61N1/365 takes precedence; evoked response A61N1/371

Abstract

Systems, methods and non-transient software media for performing sensing vector selection in an implantable cardiac device by assessing biphasic or monophasic characteristics of the cardiac signal in vectors under analysis. A factor associated with the biphasic or monophasic nature of the cardiac signal, as seen from a given sensing vector, can be inserted into the assessment of which of several available sensing vectors is considered “best” for purposes of cardiac signal analysis. Additional factors may be considered beyond the biphasic or monophasic nature including the quantity of turning points or inflections and amplitude variability.

Claims

1. A method of sensing vector selection in an implantable cardiac device, the implantable cardiac device including electrodes configured for sensing electrical signals while implanted coupled to operational circuitry configured for analyzing signals captured from the sensing electrodes, wherein the operational circuitry and electrodes are configured to define at least two sensing vectors for sensing cardiac signals, the method comprising:

for a first sensing vector, the operational circuitry establishing each of;

an estimate of signal-to-noise ratio;

an estimate of cardiac signal amplitude; and

a measure of biphasic or monophasic nature of sensed signals; and

the operational circuitry combining the signal to noise ratio, cardiac signal amplitude and measure of biphasic or monophasic nature of sensed signals to generate a sensing quality metric for the first sensing vector.

2. The method of claim 1 further comprising, for the first sensing vector, the operational circuitry sensing a plurality of cardiac cycles with selected electrodes by applying a detection profile to a sensed cardiac signal to detect a cardiac cycle, wherein the detection profile includes a refractory period and a sensing period, the refractory period being applied to a first portion of the cardiac cycle and the sensing period being applied to at least a second portion of the cardiac cycle;

wherein the step of the operational circuitry establishing an estimate of cardiac signal amplitude comprises the operational circuitry analyzing a sensed amplitude from the first portion of the cardiac cycle for each of several cardiac cycles.

3. The method of claim 1 further comprising, for the first sensing vector, the operational circuitry sensing a plurality of cardiac cycles with selected electrodes by applying a detection profile to a sensed cardiac signal to detect a cardiac cycle, wherein the detection profile includes a refractory period and a sensing period, the refractory period being applied to a first portion of the cardiac cycle and the sensing period being applied to at least a second portion of the cardiac cycle;

wherein the step of the operational circuitry establishing an estimate of signal to noise ratio includes the operational circuitry comparing a sensed amplitude from the first portion of the cardiac cycle to a sensed amplitude from the second portion of the cardiac cycle for each of several cardiac cycles.

4. The method of claim 1 further comprising, for the first sensing vector, the operational circuitry sensing a plurality of cardiac cycles with selected electrodes by applying a detection profile to a sensed cardiac signal to detect a cardiac cycle, wherein the detection profile includes a refractory period and a sensing period, the refractory period being applied to a first portion of the cardiac cycle and the sensing period being applied to at least a second portion of the cardiac cycle;

wherein the step operational circuitry establishing a measure of biphasic or monophasic nature of cardiac cycles comprises the operational circuitry comparing a sensed positive amplitude from the first portion of the cardiac cycle to a sensed negative amplitude from the first portion of the cardiac cycle for each of several cardiac cycles.

5. The method of claim 1 further comprising, for the first sensing vector, the operational circuitry sensing a plurality of cardiac cycles with selected electrodes by applying a detection profile to a sensed cardiac signal to detect a cardiac cycle, wherein the detection profile includes a refractory period and a sensing period, the refractory period being applied to a first portion of the cardiac cycle and the sensing period being applied to at least a second portion of the cardiac cycle;

wherein the step operational circuitry establishing a measure of biphasic or monophasic nature of cardiac cycles comprises the operational circuitry comparing an average sensed positive amplitude from the first portion of several of the cardiac cycles to an average sensed negative amplitude from the first portion of several of the cardiac cycles.

6. The method of claim 1 wherein the step of the operational circuitry combining the signal to noise ratio, cardiac signal amplitude and measure of biphasic or monophasic nature of cardiac signals to generate a sensing quality metric for the first sensing vector comprises the operational circuitry finding the sum or product of:

a first metric related to the signal to noise ratio;

a second metric related to the cardiac signal amplitude; and

a third metric related to the measure of biphasic or monophasic nature of cardiac signals.

7. The method of claim 1 wherein the step of the operational circuitry combining the signal to noise ratio, cardiac signal amplitude and measure of biphasic or monophasic nature of cardiac signals to generate a sensing quality metric for the first sensing vector comprises the operational circuitry establishing a sensing vector score for the first vector using the signal to noise ratio and the cardiac signal amplitude, and adjusting the score in view of the measure of biphasic or monophasic nature of cardiac signals.

8. The method of claim 1 further comprising:

for a second sensing vector, the operational circuitry establishing each of;

an estimate of signal-to-noise ratio;

an estimate of cardiac signal amplitude; and

a measure of biphasic or monophasic nature of sensed signals; and

the operational circuitry combining the signal to noise ratio, cardiac signal amplitude and measure of biphasic or monophasic nature of sensed signals to generate a sensing quality metric for the second sensing vector; and

the operational circuitry using the sensing quality metrics for the first and second sensing vectors to select from at least the first and second sensing vectors a sensing vector for use in cardiac signal analysis.

9. A method of sensing vector selection in an implantable cardiac device, the implantable cardiac device including electrodes configured for sensing electrical signals while implanted coupled to operational circuitry configured for analyzing signals captured from the sensing electrodes, wherein the operational circuitry and electrodes are configured to define at least two sensing vectors for sensing cardiac signals, the method comprising:

for the first sensing vector, the operational circuitry establishing a measure of biphasic or monophasic nature of cardiac signals;

the operational circuitry selecting a default sensing vector for use in the analysis of cardiac signals using at least one factor related to the measure of biphasic or monophasic nature of cardiac signals generated for the first sensing vector.

10. The method of claim 9 further comprising the operational circuitry combining the measure of biphasic or monophasic nature of cardiac signals for the first sensing vector with at least one other factor related to the signals captured via the first sensing vector to generate a sensing quality metric for the first sensing vector.

11. The method of claim 9 wherein the step of establishing a measure of biphasic or monophasic nature of cardiac signals comprises:

identifying a QRS portion of a cardiac cycle; and

comparing a positive peak in the QRS portion of the cardiac cycle to a negative peak in the QRS portion of the cardiac cycle.

12. The method of claim 9 wherein the step of establishing a measure of biphasic or monophasic nature of cardiac signals comprises:

detecting an event in a signal sensed along the first sensing vector;

defining a window associated with the detected event; and

comparing a positive peak in the window to a negative peak in the window.

13. An implantable cardiac device comprising:

a plurality of electrodes configured for sensing electrical signals while implanted; and

operational circuitry configured for analyzing signals received from the sensing electrodes,

wherein the operational circuitry and electrodes are configured to define at least two sensing vectors for sensing cardiac signals and the operational circuitry is configured to perform the following;

for a first sensing vector, calculating each of;

an estimate of signal-to-noise ratio;

an estimate of cardiac signal amplitude; and

a measure of biphasic or monophasic nature of sensed signals; and

combining the signal to noise ratio, cardiac signal amplitude and measure of biphasic or monophasic nature of sensed signals to generate a sensing quality metric for the first sensing vector.

14. The implantable cardiac device of claim 13 wherein:

the operational circuitry is further configured to sense a plurality of cardiac cycles with selected electrodes for the first vector by applying a detection profile to a sensed cardiac signal to detect a cardiac cycle, wherein the detection profile includes a refractory period and a sensing period, the refractory period being applied to a first portion of the cardiac cycle and the sensing period being applied to at least a second portion of the cardiac cycle; and

the operational circuitry is configured to calculate the estimate of cardiac signal amplitude by analyzing a sensed amplitude from the first portion of the cardiac cycle for each of several cardiac cycles.

15. The implantable cardiac device of claim 13 wherein:

the operational circuitry is further configured to sense a plurality of cardiac cycles with selected electrodes for the first vector by applying a detection profile to a sensed cardiac signal to detect a cardiac cycle, wherein the detection profile includes a refractory period and a sensing period, the refractory period being applied to a first portion of the cardiac cycle and the sensing period being applied to at least a second portion of the cardiac cycle; and

the operational circuitry is configured to calculate an estimate of signal to noise ratio by comparing a sensed amplitude from the first portion of the cardiac cycle to a sensed amplitude from the second portion of the cardiac cycle for each of several cardiac cycles.

16. The implantable cardiac device of claim 13 wherein:

the operational circuitry is further configured to sense a plurality of cardiac cycles with selected electrodes for the first vector by applying a detection profile to a sensed cardiac signal to detect a cardiac cycle, wherein the detection profile includes a refractory period and a sensing period, the refractory period being applied to a first portion of the cardiac cycle and the sensing period being applied to at least a second portion of the cardiac cycle; and

the operational is configured to calculate a measure of biphasic or monophasic nature of cardiac cycles by comparing a sensed positive amplitude from the first portion of the cardiac cycle to a sensed negative amplitude from the first portion of the cardiac cycle for each of several cardiac cycles.

17. The implantable cardiac device of claim 13 wherein:

the operational circuitry is further configured to sense a plurality of cardiac cycles with selected electrodes for the first vector by applying a detection profile to a sensed cardiac signal to detect a cardiac cycle, wherein the detection profile includes a refractory period and a sensing period, the refractory period being applied to a first portion of the cardiac cycle and the sensing period being applied to at least a second portion of the cardiac cycle; and

the operational circuitry is configured to calculate a measure of biphasic or monophasic nature of cardiac cycles by comparing an average sensed positive amplitude from the first portion of several of the cardiac cycles to an average sensed negative amplitude from the first portion of several of the cardiac cycles.

18. The implantable cardiac device of claim 13 wherein the operational circuitry is configured to combine the signal to noise ratio, cardiac signal amplitude and measure of biphasic or monophasic nature of cardiac signals to generate a sensing quality metric for the first sensing vector comprises the operational circuitry by finding the sum or product of:

a first metric related to the signal to noise ratio;

a second metric related to the cardiac signal amplitude; and

a third metric related to the measure of biphasic or monophasic nature of cardiac signals.

19. The implantable cardiac device of claim 13 wherein the operational circuitry is configured to combine the signal to noise ratio, cardiac signal amplitude and measure of biphasic or monophasic nature of cardiac signals to generate a sensing quality metric for the first sensing vector comprises the operational circuitry by calculating a sensing vector score for the first vector using the signal to noise ratio and the cardiac signal amplitude, and adjusting the score in view of the measure of biphasic or monophasic nature of cardiac signals.

20. The implantable cardiac device of claim 13 wherein the operational circuitry is further configured to perform the following:

for a second sensing vector, the operational circuitry calculating each of;

an estimate of signal-to-noise ratio;

an estimate of cardiac signal amplitude; and

a measure of biphasic or monophasic nature of sensed signals; and

combining the signal to noise ratio, cardiac signal amplitude and measure of biphasic or monophasic nature of sensed signals to generate a sensing quality metric for the second sensing vector; and

using the sensing quality metrics for the first and second sensing vectors to select from at least the first and second sensing vectors a sensing vector for use in cardiac signal analysis.