OPTICAL TOMOGRAPHY SENSOR AND RELATED APPARATUS AND METHODS

• US 20140276013A1
• Filed: 03/12/2014
• Published: 09/18/2014
• Est. Priority Date: 03/13/2013
• Status: Abandoned Application

• Current Assignee: Invisio Medical Inc.
• Original Assignee: Cephalogics, Llc
• Inventors: Haroud, Karim, Troller, Stefan, Khanicheh, Azadeh, Bruehwiler, Michel, Amirana, Omar, Culver, Joseph, Muehlemann, Thomas, Pace, Catherine, Caputo, Jeffery J., Herrig, Russell L.
• Application Number:
  US14/205,579
• Publication Number:
  US 20140276013A1
• Time in Patent Office: Days
• US Class Current: 600/425
• CPC Class Codes: A61B 2562/0233 Special features of optical sensors or probes classified in A61B5/00
• CPC Class Codes: A61B 2562/046 in a matrix array
• CPC Class Codes: A61B 2562/14 Coupling media or elements to improve sensor contact with skin or tissue
• CPC Class Codes: A61B 2562/146 for optical coupling
• CPC Class Codes: A61B 5/0013 Medical image data A61B1/00011, A61B6/56, A61B8/56 take precedence
• CPC Class Codes: A61B 5/0042 for the brain
• CPC Class Codes: A61B 5/0073 by tomography, i.e. reconstruction of 3D images from 2D projections A61B5/0066 takes precedence
• CPC Class Codes: A61B 5/0261 using optical means, e.g. infrared light
• CPC Class Codes: A61B 5/0275 using tracers, e.g. dye dilution
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/14553 specially adapted for cerebral tissue
• CPC Class Codes: A61B 5/4064 Evaluating the brain A61B5/031, A61B5/369, A61B5/14553 take precedence
• CPC Class Codes: A61B 5/6801 specially adapted to be attached to or worn on the body surface
• CPC Class Codes: A61B 5/6803 Head-worn items, e.g. helmets, masks, headphones or goggles
• CPC Class Codes: A61B 5/6814 Head
• CPC Class Codes: A61B 5/6831 Straps, bands or harnesses

Abstract

Optical sensors, systems, and methods are described, which may be used to provide or analyze information about a subject. The optical sensor may be placed in proximity to the subject and may include optical sources and optical detectors. The optical sources may irradiate the subject with optical signals and the optical detectors can detect signals from the subject. Analysis of the detected signals can yield information about the subject.

Claims

1. An optical sensor, comprising:

a plurality of optical sources;

a plurality of optical detectors, wherein the plurality of optical sources and the plurality of optical detectors collectively form an array and wherein at least first and second optical detectors of the plurality of optical detectors are configured to receive optical signals from at least a first optical source of the plurality of optical sources;

analog receive circuitry configured to receive an analog signal from the first optical detector of the plurality of optical detectors;

an analog-to-digital converter (ADC) configured to convert the analog signal to a digital signal,

wherein the plurality of optical sources, plurality of optical detectors, analog receive circuitry, and ADC are at least partially encapsulated in a flexible support structure configured to conform to a subject such that the first and second optical detectors of the plurality of optical detectors are configured to receive optical signals from the first optical source of the plurality of optical sources that pass through the subject.

2. The optical sensor of claim 1, wherein the optical sensor does not include any optical fibers.

3. The optical sensor of claim 1, wherein the optical sensor does not include any optical fibers configured to transmit an optical signal from a subject to an optical detector located remotely from the flexible support pad.

4. The optical sensor of claim 1, wherein the flexible support structure optically isolates the plurality of optical sources from the plurality of optical detectors.

5. The optical sensor of claim 1, wherein the first optical source is configured to emit a first wavelength of radiation and wherein a second optical source of the plurality of optical sources is configured to emit a second wavelength of radiation.

6. The optical sensor of claim 1, further comprising a digital communication line configured to couple to a host.

7. A system, comprising:

the optical sensor of claim 1,

a host coupled to the optical sensor by a digital communication line; and

a central unit coupled to the host,

wherein the central unit is configured to control display of data representative of optical signals received by the plurality of optical detectors from the plurality of optical sources.

8. The optical sensor of claim 1, wherein all optical detectors of the plurality of optical detectors are configured to receive the optical signals from the first optical source of the plurality of optical sources.

9. The optical sensor of claim 1, further comprising a microcontroller at least partially encapsulated in the flexible support pad, the microcontroller being configured to control, at least in part, operation of the plurality of optical sources and the plurality of optical detectors.

10. The optical sensor of claim 1, wherein the optical sensor further comprises analog drive circuitry configured to drive the first optical source of the plurality of optical sources.

11. The optical sensor of claim 1, wherein the flexible support structure is configured to conform to the subject such that all optical detectors of the plurality of optical detectors and all optical sources of the plurality of optical sources are configured to contact a head of the subject.

12. An optical apparatus, comprising:

a plurality of optical sources;

a plurality of optical detectors, wherein the plurality of optical sources and plurality of optical detectors are arranged in combination in an array and disposed on a flexible substrate to form a flexible array;

wherein the flexible array is configured to conform to a subject and wherein the optical apparatus has an outer surface configured to contact the subject such that the plurality of optical sources is configured to direct optical radiation toward the subject and the plurality of optical detectors is configured to detect the optical radiation after passing through the subject;

wherein at least one optical source of the plurality of optical sources has an emission point disposed within approximately 3 mm of the outer surface of the optical apparatus; and

wherein at least one optical detector of the plurality of optical detectors has a detection point disposed within approximately 3 mm of the outer surface of the optical apparatus.

13. The optical apparatus of claim 12, wherein each optical source of the plurality of optical sources has a respective emission point disposed within approximately 3 mm of the outer surface of the optical apparatus.

14. The optical apparatus of claim 12, wherein the plurality of optical sources and plurality of optical detectors are at least partially encapsulated by the flexible substrate.

15. The optical apparatus of claim 12, wherein the at least one optical source comprises a light emitting diode (LED).

16. The optical apparatus of claim 12, wherein the at least one optical source is configured to emit optical radiation having a wavelength between approximately 600 nm and approximately 1,000 nm.

17. The optical apparatus of claim 12, wherein the at least one optical source has a diameter less than approximately 7 mm.

18. The optical apparatus of claim 12, wherein the outer surface of the optical apparatus comprises respective outer surfaces of the plurality of optical sources and the plurality of optical detectors.

19. An optical sensor, comprising:

a plurality of optical sources, including a first optical source disposed at a first position of the optical sensor and configured to emit a first plurality of wavelengths and a second optical source disposed at a second position of the optical sensor and configured to emit a second plurality of wavelengths different than the first plurality of wavelengths;

a plurality of optical detectors, including a first optical detector disposed at a third location of the optical sensor and configured to detect the first plurality of wavelengths from the first optical source and the second plurality of wavelengths from the second optical source, wherein the plurality of optical sources and the plurality of optical detectors collectively form an array;

analog receive circuitry configured to receive an analog signal from the first optical detector of the plurality of optical detectors;

an analog-to-digital converter (ADC) configured to convert the analog signal to a digital signal,

wherein the plurality of optical sources, plurality of optical detectors, analog receive circuitry, and ADC are at least partially encapsulated in a flexible support structure configured to conform to a subject.

20. The optical sensor of claim 19, wherein the optical sensor does not include any optical fibers.