HYBRID OSTEOINDUCTIVE BONE GRAFT

• US 20140277569A1
• Filed: 03/13/2013
• Published: 09/18/2014
• Est. Priority Date: 03/13/2013
• Status: Abandoned Application

• Current Assignee: Warsaw Orthopedic Incorporated (Medtronic Plc)
• Original Assignee: Warsaw Orthopedic Incorporated (Medtronic Plc)
• Inventors: LANGE, ERIC C.
• Application Number:
  US13/800,977
• Publication Number:
  US 20140277569A1
• Time in Patent Office: Days
• US Class Current: 623/23.51
• CPC Class Codes: A61B 17/7062 Devices acting on, attached to, or simulating the effect of, vertebral processes, vertebral facets or ribs rib fixation devices A61B17/8076; Tools for such devices
• CPC Class Codes: A61B 2017/00004 (bio)absorbable, (bio)resorbable, resorptive for implantable prostheses A61F2210/0004
• CPC Class Codes: A61F 2/28 Bones joints A61F2/30

Abstract

A bone implant includes a first surface and a second surface. The first and second surfaces include a bioresorbable material. A third surface includes a biocompatible material disposed between the first and second surfaces. The third surface extends between a first end and a second end. The first and second ends each include an inner surface defining a cavity configured for disposal of a spinous process. The bioresorbable material of the first and second surfaces is a faster resorbing material than the biocompatible material of the third surface. The third surface provides structural integrity of the implant to maintain distraction between spinous processes so that the first and second surfaces fuse with at least a portion of the spine.

Claims

1. A bone implant, comprising:

a first surface and a second surface, the first and second surfaces comprising a bioresorbable material;

a third surface comprising a biocompatible material disposed between and connected to the first and second surfaces, the third surface extending between a first end and a second end, the first and second ends each including an inner surface defining a cavity configured for disposal of a spinous process;

wherein the bioresorbable material of the first and second surfaces is a faster resorbing material than the biocompatible material of the third surface; and

wherein the third surface provides structural integrity of the implant to maintain distraction between spinous processes so that the first and second surfaces fuse with at least a portion of the spine.

2. The bone implant as recited in claim 1, wherein the bioresorbable material of the first and second surfaces comprises demineralized bone matrix and the biocompatible material of the third surface comprises a bioresorbable material.

3. The bone implant as recited in claim 2, wherein the bioresorbable material comprises non-demineralized cortical bone.

4. The bone implant as recited in claim 2, wherein the demineralized bone matrix includes demineralized bone chips.

5. The bone implant as recited in claim 1, wherein the bioresorbable material of the first and second surfaces comprises demineralized bone matrix and the biocompatible material of the third surface comprises a non-bioresorbable material, the non-bioresorbable material comprising at least one of stainless steel alloys, commercially pure titanium, titanium alloys, Grade 5 titanium, cobalt-chrome alloys, stainless steel alloys, calcium phosphate, polyaryletherketone (PAEK), polyetheretherketone (PEEK), polyetherketoneketone (PEKK), polyetherketone (PEK), carbon-PEEK composites and PEEK-BaSO₄.

6. The bone implant as recited in claim 2, wherein the first and second surfaces are each disposed within a biocompatible polymer mesh bag.

7. The bone implant as recited in claim 6, wherein the polymer mesh bag is bioresorbable.

8. The bone implant as recited in claim 6, wherein the mesh bags of the first and second surfaces are bonded to the third surface by a fastener, an adhesive, air drying, freeze drying, heat drying, or by using a chemical cross-linking agent and/or interlocking parts.

9. The bone implant as recited in claim 6, wherein the third surface is disposed within a biocompatible polymer mesh bag, the mesh bags of the first and second surfaces being attached to the mesh bag of the third surface.

10. The bone implant as recited in claim 9, wherein the biocompatible polymer mesh bag of the third surface is bioresorbable.

11. The bone implant as recited in claim 2, wherein the first, second and third surfaces define a butterfly shape and are formed from one continuous piece of cortical bone.

12. The bone implant as recited in claim 11, wherein the first and second surfaces comprise a plurality of fenestrations configured to receive a bone material, to increase flexibility and/or to increase the surface area of the first and second surfaces.

13. A bone implant, comprising:

a first layer including an upper surface and a lower surface, the first layer comprising a bioresorbable material;

a second layer comprising a biocompatible material attached to the lower surface of the first layer, the second layer extending between a first end and a second end, the first and second ends each including an inner surface defining a cavity configured for disposal of a spinous process;

wherein the bioresorbable material of the first layer is a faster resorbing material than the biocompatible material of the second layer; and

wherein the second layer provides structural integrity of the implant to maintain distraction between spinous processes so that the first layer fuses with at least a portion of the spine.

14. The bone implant as recited in claim 13, wherein the bioresorbable material of the first layer comprises demineralized bone matrix and the biocompatible material of the second layer comprises non-demineralized cortical bone.

15. The bone implant as recited in claim 13, wherein the bioresorbable material of the first layer comprises demineralized bone matrix and the biocompatible material of the second layer comprises a non-bioresorbable material, the non-bioresorable material comprising at least one of stainless steel alloys, commercially pure titanium, titanium alloys, Grade 5 titanium, cobalt-chrome alloys, stainless steel alloys, calcium phosphate, polyaryletherketone (PAEK), polyetheretherketone (PEEK), polyetherketoneketone (PEKK), polyetherketone (PEK), carbon-PEEK composites and PEEK-BaSO₄.

16. The bone implant as recited in claim 14, wherein the first layer is disposed within a biocompatible polymer mesh bag.

17. The bone implant as recited in claim 16, wherein the polymer mesh bag is bioresorbable.

18. The bone implant as recited in claim 14, wherein the demineralized bone matrix includes demineralized bone chips.

19. A bone implant, comprising:

a first bioresorbable polymer mesh bag and a second bioresorbable polymer mesh bag, the first and second mesh bags each comprising demineralized bone chips disposed therein; and

a surface comprising cortical bone, the surface being disposed between and connected to the first and second mesh bags, the surface extending between a first end and a second end, the first and second ends each including an inner surface defining a cavity configured for disposal of a spinous process,

wherein the surface provides structural integrity of the implant to maintain distraction between spinous processes so that the demineralized bone chips fuse with at least a portion of the spine.

20. A bone implant as recited in claim 19, wherein the surface is disposed in a third bioresorbable polymer mesh bag, the first and second mesh bags being attached to the third mesh bag.