Calorimetric Microfluidic Sensor
First Claim
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1. A microfluidic sensor, the microfluidic sensor comprising:
- a microchannel that comprises a reaction site that comprises a reagent and a sample inlet, wherein the microchannel is configured to receive a liquid substance comprising a chemical at the sample inlet that travels by capillary action to the reaction site;
a temperature sensor located proximal the reaction site of the microchannel and configured to measure a temperature as a result of a reaction between the reagent and the chemical in the liquid substance; and
a controller communicatively connected to the temperature sensor, the controller receives the temperature measured by the temperature sensor and derives a concentration of the chemical in the liquid substance from the temperature.
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Abstract
A microfluidic sensor includes a microchannel that includes a reaction site with a reagent and a sample inlet. A liquid substance is received at the sample inlet and travels by capillary action to the reaction site. A temperature sensor measures a temperature as a result of a reaction between the reagent and a chemical in the liquid substance. A controller is communicatively connected to the temperature sensor, receives the temperature measured by the temperature sensor, and derives a concentration of the chemical in the liquid substance from the temperature.
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Citations
20 Claims
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1. A microfluidic sensor, the microfluidic sensor comprising:
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a microchannel that comprises a reaction site that comprises a reagent and a sample inlet, wherein the microchannel is configured to receive a liquid substance comprising a chemical at the sample inlet that travels by capillary action to the reaction site; a temperature sensor located proximal the reaction site of the microchannel and configured to measure a temperature as a result of a reaction between the reagent and the chemical in the liquid substance; and a controller communicatively connected to the temperature sensor, the controller receives the temperature measured by the temperature sensor and derives a concentration of the chemical in the liquid substance from the temperature. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A microfluidic sensor system comprising:
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At least one microfluidic sensor, comprising; as microchannel that comprises a reaction site that comprises a reagent and a sample inlet, wherein the microchannel is configured to receive a liquid substance comprising a chemical at the sample inlet that travels by capillary action to the reaction site; and a temperature sensor located proximal the reaction site of the microchannel and configured to measure a temperature as a result of a reaction between the reagent and the chemical in the liquid substance; a controller communicatively connected to the at least one microfluidic sensor, the controller receives the temperature measured by the temperature sensor of at least one microfluidic sensor and derives a concentration of the chemical in the liquid substance from the temperature; a graphical display operated by the controller to present the derived concentration of the chemical in the liquid substance. - View Dependent Claims (14, 15, 16, 17, 18)
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19. A method of chemical sensing, the method comprising:
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Selecting a reagent specific to a chemical to be sensed; Providing a microfluidic sensor comprising; a microchannel that comprises a sample inlet and a reaction site that comprises the selected reagent; and a temperature sensor located proximal the reaction site; receiving a liquid sample at the sample inlet, wherein the liquid sample travels to the reaction site by capillary action; measuring a temperature at the reaction site, wherein the temperature at the reaction site changes due to a reaction between the reagent and the chemical to be sensed; calculating a change in the detected temperature; determining, from the change in the detected temperature, if the chemical to be sensed is present in the liquid sample; and visually presenting the determination. - View Dependent Claims (20)
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Specification