CYCLIC ANTIMICROBIAL PEPTIDES
First Claim
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1. A cyclic peptide, or variant thereof, comprising amino acids according to the formula I:
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((X)l(Y)m)n
(I)wherein l and m are integers from 0 to 10 such that both l and m are not 0, n is an integer from 1 to 10, andX and Y, which may be the same or different, are an amino acid selected from the group consisting of;
arginine, lysine and ornithine.
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Abstract
The present invention relates to cyclic cationic peptides and their use in the treatment of microbial infections.
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Citations
19 Claims
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1. A cyclic peptide, or variant thereof, comprising amino acids according to the formula I:
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((X)l(Y)m)n
(I)wherein l and m are integers from 0 to 10 such that both l and m are not 0, n is an integer from 1 to 10, and X and Y, which may be the same or different, are an amino acid selected from the group consisting of;
arginine, lysine and ornithine. - View Dependent Claims (2, 10, 13)
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- 3. A cyclic peptide comprising from 3 to 15 contiguous arginine residues.
- 6. A cyclic peptide comprising 7 contiguous arginine residues.
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9. A cyclic peptide consisting of 7 arginine residues.
Specification