PREDICTION, VISUALIZATION, AND CONTROL OF DRUG DELIVERY BY INFUSION PUMPS
8 Assignments
0 Petitions
Accused Products
Abstract
Systems for predicting a drug delivery profile as described herein include at least one drug pump and/or a controllable valve that produce a drug flow. The drug pump and/or controllable valve dispense at least a first drug. The system also includes at least one carrier fluid pump and/or another controllable valve that produces a carrier fluid flow, a flow junction structure configured to receive the drug flow and the carrier fluid flow to produce a mixed flow, and a fluid path for carrying the mixed flow between the flow junction structure and a delivery point. The system further includes a processing device configured to predict the drug delivery profile at the delivery point based on determining a predicted time variation of drug concentration at the delivery point using at least a model of the mixed flow. The model includes a plurality of parameters related to propagation of the mixed flow through the fluid path.
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Citations
39 Claims
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1-20. -20. (canceled)
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21. A system for controlling a drug delivery profile, the system comprising:
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at least one drug pump that produces a drug flow, wherein the at least one drug pump dispenses at least a first drug; at least one carrier fluid pump that produces a carrier fluid flow; a flow junction structure configured to receive the drug flow and the carrier fluid flow to produce a mixed flow; a fluid path for carrying the mixed flow between the flow junction structure and a delivery point; and a control module configured to control the drug delivery profile at the delivery point by controlling a drug flow rate and a carrier fluid flow rate such that a ratio between the drug flow rate and the carrier fluid flow rate is substantially fixed over a range of time, and the mixed flow is varied to achieve a particular drug delivery profile. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29, 30)
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31-34. -34. (canceled)
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35. A method for predicting delivery rate at a delivery point, the method comprising:
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receiving, at a processing device, one or more operating parameters related to a first container that dispenses a drug and a second container that dispenses a carrier fluid, wherein at least one of the drug and the carrier fluid is dispensed at a predefined pressure; and determining, by the processing device, a delivery rate of the drug at the delivery point by predicting time variation of a concentration of the drug at the delivery point based at least on a mathematical model of a mixed flow through a fluid path that terminates at the delivery point, wherein the mixed flow includes the drug and the carrier fluid, and the model includes the one or more operating parameters and a plurality of flow-parameters related to the mathematical model of the mixed flow. - View Dependent Claims (36, 37, 38)
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39. A system for controlling a drug delivery profile, the system comprising:
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a first controllable valve that controls a flow of a drug; a second controllable valve that controls a carrier fluid flow; a flow junction structure configured to receive the drug flow and the carrier fluid flow to produce a mixed flow; a fluid path for carrying the mixed flow between the flow junction structure and a delivery point; and a control module configured to control the drug delivery profile at the delivery point by controlling a drug flow rate and a carrier fluid flow rate such that a ratio between the drug flow rate and the carrier fluid flow rate is substantially fixed over a range of time, and the mixed flow is varied to achieve a particular drug delivery profile.
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Specification