Combination Immunotherapy for the Treatment of Cancer
First Claim
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1. A method of treating cancer in a patient comprising administering to the patient simultaneously or sequentially a composition comprising a blocking anti-PD-1 antibody and an ICOS ligand.
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Abstract
Agonists to ICOS in combination with a blocking agent to a T cell inhibitory receptor (e.g., CTLA-4, PD-1, etc.) are demonstrated herein to be useful for the treatment of tumors.
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Citations
9 Claims
- 1. A method of treating cancer in a patient comprising administering to the patient simultaneously or sequentially a composition comprising a blocking anti-PD-1 antibody and an ICOS ligand.
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Specification