APPARATUS AND METHOD FOR DETECTING PHRENIC NERVE STIMULATION

• US 20140309538A1
• Filed: 04/10/2013
• Published: 10/16/2014
• Est. Priority Date: 04/10/2013
• Status: Abandoned Application

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Inventors: Coppola, Benjamin, More, Rohan A.
• Application Number:
  US13/860,351
• Publication Number:
  US 20140309538A1
• Time in Patent Office: Days
• US Class Current: 600/483
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/389 Electromyography [EMG]
• CPC Class Codes: A61B 5/395 Details of stimulation, e.g. nerve stimulation to elicit EMG response
• CPC Class Codes: A61B 5/7221 Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence

Abstract

An apparatus and method for detecting phrenic nerve stimulation (PNS) including computing a power spectral density (PSD) of spatial data of a sensor; determining two spectral magnitudes from the PSD; computing a ratio of the two spectral magnitudes; and comparing the ratio to a threshold to detect PNS. In one example, detecting PNS includes computing a PSD of spatial data of an externally placed sensor; determining a diaphragmatic spectral magnitude and a respiratory motion spectral magnitude from the PSD; and computing a ratio of the diaphragmatic spectral magnitude to the respiratory motion spectral magnitude to detect PNS. In one example, detecting PNS includes computing an oscillation amplitude of spatial data of a sensor; computing a baseline wander amplitude of the spatial data of the sensor; computing a ratio of the oscillation amplitude to the baseline wander amplitude; and comparing the ratio to a threshold to detect PNS.

Claims

1. A method for detecting phrenic nerve stimulation (PNS) comprising:

computing a power spectral density (PSD) of spatial data of a sensor;

determining a first spectral magnitude and a second spectral magnitude from the power spectral density (PSD);

computing a ratio of the first spectral magnitude to the second spectral magnitude; and

comparing the ratio to a threshold, wherein if the ratio is equal or greater than the threshold, determining that phrenic nerve stimulation (PNS) is present, and wherein if the ratio is less than the threshold, determining that no PNS or minimal PNS is present.

2. The method of claim 1, wherein the spatial data includes one or more of the following:

position data of the sensor over time or orientation data of the sensor over time.

3. The method of claim 1, further comprising computing the power spectral density (PSD) by taking a Fourier transform of the spatial data.

5. The method of claim 1, further comprising computing the power spectral density (PSD) by one of the following:

using parametric spectral estimation of the spatial data;

using non-parametric spectral estimation of the spatial data;

taking a wavelet transform of the spatial data;

taking a periodogram of the spatial data;

or taking a periodogram of a moving average of the spatial data.

6. The method of claim 1, wherein the sensor is one of the following:

an electromagnetic sensor, a ultrasonic sensor, an acoustic sensor or an impedance-based sensor.

7. The method of claim 6, wherein the sensor is placed internally in a patient.

8. The method of claim 7, wherein the sensor is placed within one of the following locations of the patient:

a chest cavity, a heart tissue or a blood vessel.

9. The method of claim 7, wherein the sensor is placed within a coronary sinus branch.

10. The method of claim 6, wherein the sensor is placed externally on a patient'"'"'s torso area.

11. The method of claim 1, wherein the sensor comprises a set of multiple sensors.

12. The method of claim 1, wherein the first spectral magnitude is a cardiac motion spectral magnitude, and the second spectral magnitude is a respiratory motion spectral magnitude.

13. The method of claim 12, wherein the threshold is derived from a right ventricle (RV) pacing configuration.

14. The method of claim 1, further comprising identifying the phrenic nerve stimulation (PNS) with a pacing vector and marking the pacing vector with a marker.

15. The method of claim 1, further comprising repeating the steps of claim 1 for a plurality of pacing vectors, wherein each of the plurality of pacing vectors is different.

4. The method of claim 4, further comprising taking a magnitude squared of the Fourier transform.

16. A device for detecting phrenic nerve stimulation (PNS) comprising a processor and a memory, the memory containing program code executable by the processor for performing the following:

computing a power spectral density (PSD) of spatial data of a sensor;

determining a first spectral magnitude and a second spectral magnitude from the power spectral density (PSD);

computing a ratio of the first spectral magnitude to the second spectral magnitude; and

comparing the ratio to a threshold, wherein if the ratio is equal or greater than the threshold, determining that phrenic nerve stimulation (PNS) is present and wherein if the ratio is less than the threshold, determining that no PNS or minimal PNS is present.

17. The device of claim 16, wherein the first spectral magnitude is a cardiac motion spectral magnitude, and the second spectral magnitude is a respiratory motion spectral magnitude.

18. The device of claim 16, wherein the memory further comprising program code for identifying the phrenic nerve stimulation (PNS) with a pacing vector and marking the pacing vector with a marker.

19. The device of claim 16, wherein the device comprises a sensor system, a programmer system and a communication channel coupling the sensor system and the programmer system, and wherein the sensor is part of the sensor system.

20. A method for detecting phrenic nerve stimulation (PNS) comprising:

computing an oscillation amplitude of spatial data of a sensor;

computing a baseline wander amplitude of the spatial data of the sensor;

computing a ratio of the oscillation amplitude to the baseline wander amplitude; and

comparing the ratio to a threshold, wherein if the ratio is equal or greater than the threshold, determining that phrenic nerve stimulation (PNS) is present, and wherein if the ratio is less than the threshold, determining that no PNS or minimal PNS is present.