METHODS AND APPARATUS FOR DELIVERING OCULAR IMPLANTS INTO THE EYE

• US 20140323944A1
• Filed: 07/14/2014
• Published: 10/30/2014
• Est. Priority Date: 11/20/2007
• Status: Active Grant

• Current Assignee: Alcon Incorporated
• Original Assignee: Andrew T. Schieber, Charles L. Euteneuer, Edward Matthees, John Wardle
• Inventors: SCHIEBER, Andrew T., WARDLE, John, EUTENEUER, Charles L., MATTHEES, Edward
• Granted Patent: US 9,050,169 B2
• Time in Patent Office: Days
• US Class Current: 604/8
• CPC Class Codes: A61B 17/3417 Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating syringe needles A61M5/32; dilators A61M29/00
• CPC Class Codes: A61B 17/3468 for implanting or removing devices, e.g. prostheses, implants, seeds, wires devices for implanting seeds A61M37/0069
• CPC Class Codes: A61F 2/148 Implantation instruments specially adapted therefor
• CPC Class Codes: A61F 2/15 Implant having one or more holes, e.g. for nutrient transport, for facilitating handling
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

A method of deploying an ocular implant into Schlemm'"'"'s canal of a human eye including the following steps: inserting a distal tip of a delivery tool within an anterior chamber of the eye through trabecular meshwork of the eye into Schlemm'"'"'s canal of the eye; and advancing an ocular implant through a curved portion and a distal opening of the delivery tool to place a body portion of the ocular implant in Schlemm'"'"'s canal and an inlet portion of the ocular implant in the anterior chamber.

Claims

1. A cannula for an ocular implant delivery system comprising a member having an opening at a distal end and a lumen extending proximally within the member along a longitudinal axis from the opening, the member having a first side and a second side opposite the first side, the member extending further distally on the first side than on the second side to the opening, the member comprising:

a distal tip;

a curved portion disposed proximal to the distal tip, the longitudinal axis through the curved portion defining a curve plane, the second side of the member being disposed radially inward of the first side of the member in the curved portion;

a straight portion proximal to the curved portion;

the distal tip being adapted to be inserted into an anterior chamber of a human subject'"'"'s eye, through trabecular meshwork and into Schlemm'"'"'s canal of the eye, the proximal portion of the member being adapted to extend from a location exterior to the eye when the distal tip is in Schlemm'"'"'s canal of the eye, the cannula being further adapted to cooperate with an advancement mechanism to advance an ocular implant through the tubular member toward and through the opening into Schlemm'"'"'s canal of the eye when the distal tip is disposed in Schlemm'"'"'s canal, the curved portion of the member having a curve adapted to achieve substantially tangential entry of the ocular implant into Schlemm'"'"'s canal.

2. The cannula of claim 1 wherein an elliptically shaped surface at the distal end of the member surrounds the opening.

3. The cannula of claim 2 wherein the elliptically shaped surface is disposed in a plane oriented at a pitch angle of 5-35 degrees with respect to the longitudinal axis of the member.

4. The cannula of claim 1 wherein the opening has a first axis perpendicular to a second axis, the first axis being longer than the second axis.

5. The cannula of claim 4 wherein the second axis is perpendicular to the curve plane of the member.

6. The cannula of claim 4 wherein the second axis is disposed at a roll angle of 100°

-110°

with respect to the curve plane.

7. The cannula of claim 1 wherein the distal tip is disposed in the curve plane.

8. The cannula of claim 1 wherein the distal tip is disposed outside of the curve plane.

9. The cannula of claim 1 wherein an opening surface at the distal end of the member surrounds the opening to define a tongue extending proximally from the tip on the first side of the body, the opening being disposed opposite to the tongue on the second side of the body.

10. The cannula of claim 9 wherein the opening surface has a first section disposed in a plane forming a first section angle greater than 0°

and less than 90°

with respect to the longitudinal axis and a notched section having an angle with respect to the longitudinal axis that varies from an angle less than that of the first section to an angle greater than the first section.

11. The cannula of claim 9 wherein the tongue comprises a first region in which circumferential material coverage of the body around the lumen increases from a first point to a second point proximal to the first point, a second region in which circumferential material coverage of the body around the lumen decreases from the second point to a third point proximal to the second point, and a third region in which circumferential material coverage of the body around the lumen increases from the third point to a fourth point proximal to the third point.

12. The cannula of claim 11 wherein the body has complete circumferential material coverage around the lumen proximal to the fourth point.

13. The cannula of claim 9 wherein the tongue is sized and configured to depress trabecular meshwork and Schlemm'"'"'s canal tissue of the eye in a tenting area to form a ramp for delivery of the ocular implant.

14. The cannula of claim 1 wherein the member further comprises a second straight portion distal to the curved portion.

15. The cannula of claim 1 wherein a diameter of the member at a first location is greater than a diameter of the member at a second location distal to the first location and proximal to the opening.

16. The cannula of claim 15 wherein the diameter of the member tapers from the first location to the second location.

17. The cannula of claim 1 wherein the lumen has a circular cross-sectional shape.

18. The cannula of claim 1 further comprising a hub proximal to the straight portion.