WATER SOLUBLE METAL-ORGANIC FRAMEWORKS (MOFS)

• US 20140330020A1
• Filed: 10/03/2012
• Published: 11/06/2014
• Est. Priority Date: 10/03/2011
• Status: Active Grant

• Current Assignee: Council of Scientific & Industrial Research
• Original Assignee: Council of Scientific & Industrial Research
• Inventors: Banerjee, Rahul, Sahoo, Subhash Chandra, Kundu, Tanay
• Granted Patent: US 9,290,518 B2
• Time in Patent Office: Days
• US Class Current: 546/12
• CPC Class Codes: C07F 3/06 Zinc compounds

Abstract

An efficient, one step solution state processing of Proton Conducting Homochiral Metal Organic Framework has been achieved by using derivate of amino acid and Zn(II) salt as a MOF constructor. Control over MOF solubility as well as proton conductivity has also been achieved by judicious of the ligand architecture. This invention will lead the way for ease preparation of MOF films for industrial application.

Claims

1. Stable, water soluble and biocompatible metal organic frameworks (MOFs) of formula I

[M(l/d-L_X)(X)](H₂O)₂ 

 

Formula I

wherein

M is a metal selected from the group consisting of Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Y, Zr, Nb, Mo, Tc, Ru, Rh, Pd, Cd, La, W, Os, Ir, Pt, Au, Hg, Sm, Eu, Gd, Tb, Dy, Ho, Al, Ga, In, Ge, Sn, Pb), Li, Na, K, Rb, Cs, Mg, Ca, Sr or Ba;

L is derivatives of an amino acid ligand of formula II

2. The metal organic frameworks according to claim 1, wherein representative compounds of said MOF comprising:

[Zn(l-L1_CH3COO)(CH₃COO)](H₂O)₂ (5);

wherein R1=isopropyl, R2=pyridyl in ligand L;

[Zn(l-L1_HCOO)(HCOO)](H₂O)₂ (6);

wherein R1=isopropyl, R2=pyridyl in ligand L;

[Zn(l-L2_Cl)(Cl)](H₂O)₂ (7);

wherein R1=methyl, R2=pyridyl in ligand L;

[Zn(l-L2_Br)(Br)](H₂O)₂ (8);

wherein R1=methyl, R2=pyridyl in ligand L;

[Zn(l-L2_CH3COO)(CH₃COO)](H₂O)₂ (9);

wherein R1=methyl, R2=pyridyl in ligand L;

[Zn(l-L2_HCOO)(HCOO)](H₂O)₂ (10);

wherein R1=methyl, R2=pyridyl in ligand L.

4. The metal organic frameworks as claimed in claim 1, wherein water solubility of compound of formula 1

5. The metal organic frameworks according to claim 1, wherein the biocompatible metal organic frameworks are useful for proton conduction.

6. The metal organic frameworks according to claim 1, wherein proton conductivity of the said MOFs is in the range of 3.6×

10<sup>−

5</sup> S cm<sup>−

1</sup> to 3.5×

10<sup>−

3</sup> S cm<sup>−

1</sup>.

3. The metal organic frameworks according to claim 3, wherein the derivative of an amino acid ligands of formula II is selected from the group consisting of:

7. A process for preparation of biocompatible water soluble metal organic frameworks (MOF) prepared under hydrothermal conditions and the said process comprising the steps of:

a) adding metal salt to an aqueous solution of derivative of an amino acid in the ratio ranging between 1;

1 to 1;

2 followed by sonicating to obtain clear solution;

b) keeping the tightly capped solution as obtained in step (a) undisturbed at temperature in the range of 50 to 90°

C. to obtain transparent crystals of water soluble metal organic framework (MOF) of formula I.

8. The process according to claim 7, wherein the metal salt is zinc acetate.