FRACTIONALIZED STIMULATION PULSES IN AN IMPLANTABLE STIMULATOR DEVICE

• US 20140336726A1
• Filed: 07/11/2014
• Published: 11/13/2014
• Est. Priority Date: 05/15/2008
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Parramon, Jordi, Carbunaru, Rafael, Haller, Matt I.
• Granted Patent: US 9,393,423 B2
• Time in Patent Office: Days
• US Class Current: 607/59
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36125 Details of circuitry or electric components
• CPC Class Codes: A61N 1/36171 Frequency
• CPC Class Codes: A61N 1/36175 Pulse width or duty cycle
• CPC Class Codes: A61N 1/36178 Burst or pulse train parameters
• CPC Class Codes: A61N 1/37235 Aspects of the external programmer

Abstract

A method for configuring stimulation pulses in an implantable stimulator device having a plurality of electrodes is disclosed, which method is particularly useful in adjusting the electrodes by current steering during initialization of the device. In one aspect, a set of ideal pulses for patient therapy is determined, in which at least two of the ideal pulses are of the same polarity and are intended to be simultaneous applied to corresponding electrodes on the implantable stimulator device during an initial duration. These pulses are reconstructed into fractionalized pulses, each comprised of pulse portions. The fractionalized pulses are applied to the corresponding electrodes on the device during a final duration, but the pulse portions of the fractionalized pulses are not simultaneously applied during the final duration.

Claims

1. An implantable stimulator device (ISD), comprising:

a memory configured to store a first frequency, wherein the first frequency comprises a stimulation frequency that is considered therapeutically effective for a patient;

logic configured to define a group of a plurality of pulses, wherein the pulses within the group have a second frequency greater than or equal to 2000 Hz; and

source or sink circuitry configured to periodically apply the group of the pulses to at least one electrode at the first frequency.

2. The device of claim 1, wherein the pulses within the group have a duty cycle of approximately 50%.

3. The device of claim 1, wherein the second frequency is less than or equal to 10000 Hz.

4. The device of claim 1, further comprising a receiver configured to wirelessly receive the first frequency from a device external to the ISD.

5. The device of claim 4, wherein the first frequency is considered therapeutically effective for a patient by determining the first frequency to be therapeutically effective for a particular patient at the external device.

6. The device of claim 1, further comprising a receiver configured to wirelessly receive from a device external to the ISD a first duration at which the group of the plurality of pulses are configured to be periodically applied by the source or sink circuitry, wherein the memory is further configured to store the first duration.

7. The device of claim 1, wherein the pulses in the group are either only anodic or only cathodic.

8. The device of claim 1, wherein the source or sink circuitry comprises constant current source or sink circuitry configured to periodically apply the group of the pulses to at least one electrode at a constant current.

9. The device of claim 1, further comprising at least one lead, wherein the at least one electrode is carried by the at least one lead.

10. The device of claim 1, wherein the logic is configured to define the pulses in the group in a single timing channel.

11. A method for creating pulses in an implantable stimulator device (ISD), comprising:

receiving a first frequency at the ISD, wherein the first frequency comprises a stimulation frequency that is considered therapeutically effective for a patient; and

constructing in the ISD groups of a plurality of pulses that can be applied to at least one electrode of the ISD, wherein the pulses within each group are constructed at a second frequency greater than or equal to 2000 Hz, and wherein the groups are constructed at the first frequency.

12. The method of claim 11, wherein the pulses within each group have a duty cycle of approximately 50%.

13. The method of claim 11, wherein the second frequency is less than or equal to 10000 Hz.

14. The method of claim 11, wherein the first frequency is wirelessly received from a device external to the ISD.

15. The method of claim 14, wherein the first frequency is considered therapeutically effective for the patient by further determining that the first frequency is therapeutically effective for the patient at the external device.

16. The method of claim 11, further comprising wirelessly receiving a first duration from a device external to the ISD for each group of the plurality of pulses.

17. The method of claim 16, further comprising determining that the first duration is therapeutically effective for the patient at the external device.

18. The method of claim 11, wherein the pulses in each group are either only anodic or only cathodic.

19. The method of claim 11, wherein the pulses in each group are constructed with a constant current.

20. The method of claim 11, wherein the groups of the pulses are constructed in a single timing channel in the ISD.

21. The method of claim 11, wherein the groups are constructed with a time between successive groups during which the pulses are not applied.

22. A method for providing stimulation to at least one electrode of an implantable stimulator device (ISD) implanted in a patient, comprising:

receiving a first frequency at the ISD, wherein the first frequency comprises a stimulation frequency determined to be therapeutically effective for the patient;

constructing in the ISD a group of a plurality of pulses, wherein the pulses within the group have a second frequency greater than or equal to 2000 Hz; and

periodically applying the group of the pulses to the at least one electrode at the first frequency.

23. The method of claim 22, wherein the second frequency is less than or equal to 10000 Hz.

24. The method of claim 22, wherein the first frequency is wirelessly received from a device external to the ISD.

25. The method of claim 24, wherein the first frequency is determined to be therapeutically effective for the patient at the external device.

26. The method of claim 22, wherein the pulses in each group are either only anodic or only cathodic, and are applied to the at least one electrode at a constant current.

27. The method of claim 22, wherein the ISD is coupled to first and second leads, and wherein the first and second leads are positioned parallel to the patient'"'"'s spinal cord.

28. The method of claim 27, wherein the first and second leads are positioned to the right and left of a physiological midline of the patient'"'"'s spinal cord.

29. The method of claim 27, wherein the first and second leads are positioned within an epidural space of the patient'"'"'s spinal cord.

30. The method of claim 22, wherein the groups are periodically applied to the at least one electrode with a time between successive groups during which the pulses are not applied.