FIBER OPTIC FLOW AND OXYGENATION MONITORIONG USING DIFFUSE CORRELATION AND REFLECTANCE
First Claim
Patent Images
1. A device, comprising:
- a first illuminator fiber having a distal end; and
a first detector fiber having a distal end located at a first distance from the distal end of the first illuminator fiber,the first illuminator fiber being in optical communication with an illumination source, andthe first detector fiber being capable of in optical communication with a first illumination detector.
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Abstract
Disclosed are fiber optic devices and related methods that allow for measurement of blood flow and oxygenation in real time. These devices have particular application to the spinal cord. Such devices have applicability in, for example, the care of military members sustaining combatant and noncombatant spinal injuries, as well as to civilians. The devices also have utility in the acute and subacute management of spine trauma, enhancing the efficacy of interventions aimed at the prevention of secondary ischemic injury, and ultimately improving neurologic outcome.
16 Citations
45 Claims
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1. A device, comprising:
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a first illuminator fiber having a distal end; and a first detector fiber having a distal end located at a first distance from the distal end of the first illuminator fiber, the first illuminator fiber being in optical communication with an illumination source, and the first detector fiber being capable of in optical communication with a first illumination detector. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
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25. A method, comprising:
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illuminating, with light emitted from the distal end of an illuminator fiber, a first region of tissue proximate to the spinal cord; collecting, with a first detector fiber having a distal end at a distance from the distal end of the illuminator fiber, illumination from the first region of tissue; and correlating the collected illumination to a level of tissue blood oxygenation, a level of tissue oxy-hemoglobin, a level of tissue de-oxy-hemoglobin, a level of tissue blood flow, water content, lipid presence, tracer presence, or any combination thereof. - View Dependent Claims (26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40)
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41. A device, comprising:
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an elongate fiber optic probe being adapted for insertion into the epidural space, the intrathecal space, or both; the fiber optic probe and a first illuminator fiber having a distal end being integrated; a first detector fiber being integrated with the fiber optic probe, the first detector fiber having a distal end located at a first distance from the distal end of the first illuminator fiber, the first illuminator fiber being capable of in optical communication with an illumination source, the first detector fiber being capable of in optical communication with a first illumination detector. - View Dependent Claims (42)
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43. A method, comprising:
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illuminating, with light emitted from the distal end of an illuminator fiber integrated with a fiber optic probe, a first region of tissue proximate to the spinal cord; collecting, with a first detector fiber integrated with the fiber optic probe and having a distal end at a distance from the distal end of the illuminator fiber, illumination from the first region of tissue; and correlating the collected illumination to a level of tissue blood oxygenation, a level of tissue oxy-hemoglobin, a level of tissue de-oxy-hemoglobin, a level of tissue blood flow, water content, lipid presence, tracer presence, or any combination thereof, or any combination thereof. - View Dependent Claims (44, 45)
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Specification