PERCUTANEOUS DRUG DELIVERY APPARATUS

• US 20140343500A1
• Filed: 07/29/2014
• Published: 11/20/2014
• Est. Priority Date: 02/12/2010
• Status: Active Grant

• Current Assignee: Renishaw PLC
• Original Assignee: Renishaw PLC
• Inventors: FIELDER, Paul David, GILL, Steven S., LEWIS, Trefor Owen, VICK, Andrew Samuel
• Granted Patent: US 10,596,362 B2
• Time in Patent Office: Days
• US Class Current: 604/175
• CPC Class Codes: A61B 17/1739 specially adapted for particular parts of the body
• CPC Class Codes: A61M 2039/0261 Means for anchoring port to the body, or ports having a special shape or being made of a specific material to allow easy implantation/integration in the body
• CPC Class Codes: A61M 2039/0276 for introducing or removing fluids into or out of the body
• CPC Class Codes: A61M 2039/0282 with implanted tubes connected to the port
• CPC Class Codes: A61M 2039/1083 having a plurality of female connectors, e.g. Luer connectors
• CPC Class Codes: A61M 2039/1088 having a plurality of male connectors, e.g. Luer connectors
• CPC Class Codes: A61M 2205/02 characterised by a particular materials
• CPC Class Codes: A61M 2205/7518 bacterial
• CPC Class Codes: A61M 2210/0687 Skull, cranium
• CPC Class Codes: A61M 39/0247 Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body peritoneal dialysis catheters A61M1/285; tracheostomy devices A61M16/0465; measuring pressure within the body A61B5/03; colostomy devices A61F5/445; gastrotomy feeding tubes A61J15/0015; means for fixing a feeding tube outside of the body A61J15/0053
• CPC Class Codes: A61M 39/105 Multi-channel connectors or couplings, e.g. for connecting multi-lumen tubes multi-channel connectors in general F16L37/56
• CPC Class Codes: A61M 39/223 Multiway valves
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/36 with means for eliminating or preventing injection or infusion of air into body dialysis systems, blood oxygenators A61M1/14; haemofiltration equipment A61M1/34; automatic tube cut-off A61M39/281

Abstract

An implantable percutaneous fluid delivery device is described that includes a subcutaneous base portion having one or more ports for supplying fluid to one or more implanted catheter devices and a percutaneous portion including an extracorporeal surface. The one or more ports of the subcutaneous base portion are accessible from the extracorporeal surface of the percutaneous portion. The subcutaneous base portion is at least partially insertable into a complementary recess formed in a bone, the subcutaneous base portion including one or more features for gripping the internal surface of such a complementary recess thereby directly anchoring the subcutaneous base portion to the bone. The device may be used to route fluid to neurosurgical catheters optionally via a router unit.

Claims

1. An implantable percutaneous fluid delivery device comprising:

a subcutaneous base portion comprising one or more ports for supplying fluid to one or more implanted catheter devices, and

a percutaneous portion comprising an extracorporeal surface, the one or more ports of the subcutaneous base portion being accessible from the extracorporeal surface of the percutaneous portion,

wherein the subcutaneous base portion is at least partially insertable into a complementary recess formed in a bone, the complementary recess having an internal surface and the subcutaneous base portion comprising one or more features for gripping the internal surface of the complementary recess thereby directly anchoring the subcutaneous base portion to the bone.

2. The device according to claim 1, wherein the one or more features enable the subcutaneous base portion to be retained in the complementary recess by a friction fit.

3. The device according to claim 1, wherein the one or more features comprise one or more protrusions provided on an outer surface of the subcutaneous base portion, the one or more protrusions allowing the device to be secured in the complementary recess by a push-fit action.

4. The device according to claim 1, wherein the subcutaneous base portion comprises at least one of a rough surface and a coating that promotes osseointegration.

5. The device according to claim 1, wherein the subcutaneous base portion comprises a protruding lip for engaging an outer surface of a bone around the periphery of a recess formed in that bone.

6. The device according to claim 1, wherein the subcutaneous base portion comprises a first part that is attachable to the percutaneous portion and an elongate section that protrudes from the first part, wherein, when the device is implanted in the body, a whole of the elongate section is located within a recess formed in the bone.

7. The device according to claim 6, wherein the subcutaneous base portion comprises a second part, the first and second parts being connected by the elongate section.

8. The device according to claim 6, wherein the elongate section is at least 10 mm long.

9. The device according to claim 1, comprising two or more ports.

10. The device according to claim 1, comprising at least one of a bacterial filter and an air vent.

11. The device according to claim 1, wherein the subcutaneous base portion comprises at least one subcutaneous fluid inlet for receiving fluid from at least one remotely implanted pump, wherein fluid received at the at least one subcutaneous fluid inlet is routable to the one or more ports.

12. The device according to claim 1, wherein at least part of the percutaneous portion comprises a peripheral surface that encourages tissue ingrowth.

13. A Neurological apparatus comprising;

an implantable percutaneous fluid delivery device according to claim 1,

a supply tube having one or more lumens,

an implantable router unit having one or more inlets for routing fluid to one or more outlets, and

one or more intraparenchymal catheter devices,

wherein the one or more ports of the percutaneous fluid delivery device are connected to the one or more inlets of the router unit via the supply tube and the one or more intraparenchymal catheter devices are connected to the one or more outlets of the implantable router unit.

14. The apparatus according to claim 13, comprising a external fluid connector unit for cooperating with the extracorporeal surface of the percutaneous fluid delivery device to provide fluid communication with the ports.

15. A jig for implanting a percutaneous fluid delivery device of claim 1, wherein the jig provide a template for cutting a recess in bone into which the subcutaneous base portion of the percutaneous fluid delivery device can be fitted.

16. An implantable percutaneous fluid delivery device comprising:

a subcutaneous base portion comprising one or more ports for supplying fluid to one or more implanted catheter devices, and

a percutaneous portion comprising an extracorporeal surface, the one or more ports of the subcutaneous base portion being accessible from the extracorporeal surface of the percutaneous portion,

wherein the subcutaneous base portion is at least partially insertable into a complementary recess formed in a bone and at least part of the subcutaneous base portion osseointegrates following implantation.

17. The device according to claim 16, wherein the subcutaneous base portion comprises at least one of a rough surface and a coating that promotes osseointegration.