CARTRIDGE FOR PREPARING A SAMPLE FLUID CONTAINING CELLS FOR ANALYSIS
First Claim
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1. A cartridge configured for use in a blood analyzer, the cartridge comprising:
- a substantially rigid frame;
a flow path within the rigid frame;
at least one opening in the substantially rigid frame configured to align and stabilize a capillary tube; and
a seal within the flow path, wherein the seal is configured to temporarily obstruct flow through at least a portion of the flow path, and wherein the seal is configured to open in response to a force exerted via a capillary tube inserted into the at least one opening.
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Abstract
A cartridge configured for use in a blood analyzer is provided. The cartridge may include a substantially rigid frame, a flow path within the rigid frame, at least one opening in the substantially rigid frame configured to align and stabilize a capillary tube, and a seal within the flow path. The seal may be configured to temporarily obstruct flow through at least a portion of the flow path. The seal may also be configured to open in response to a force exerted via a capillary tube inserted into the at least one opening.
18 Citations
25 Claims
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1. A cartridge configured for use in a blood analyzer, the cartridge comprising:
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a substantially rigid frame; a flow path within the rigid frame; at least one opening in the substantially rigid frame configured to align and stabilize a capillary tube; and a seal within the flow path, wherein the seal is configured to temporarily obstruct flow through at least a portion of the flow path, and wherein the seal is configured to open in response to a force exerted via a capillary tube inserted into the at least one opening. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A cartridge configured for use in a blood analyzer, the cartridge comprising:
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a substantially rigid portion; a flexible sheet fixed to the rigid portion, wherein the flexible sheet includes a cap disposed over a depression formed in the rigid portion to form a first reservoir; a sample fluid inlet formed in the rigid portion, the sample fluid inlet being configured to align and stabilize a capillary tube; and at least one flow path formed in the rigid portion and configured to establish fluid communication between the sample fluid inlet and the first reservoir. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. A cartridge configured for use in a blood analyzer, the cartridge comprising:
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a first blood sample inlet; a first reservoir containing at least one high molecular weight polymer, a buffer, and a sphering agent; a first channel connecting the first blood sample inlet and the first reservoir; a second reservoir; a second channel connecting the first reservoir to the second reservoir; a micro-channel flow connected to the second reservoir; a second blood sample inlet; a third reservoir containing a first stain; a third channel connecting the second blood sample inlet to the third reservoir; a fourth reservoir; a fourth channel connecting the third reservoir to the fourth reservoir;
a fifth reservoir containing a second stain;a fifth channel connecting the fourth reservoir to the fifth reservoir, wherein the fifth reservoir is flow connected to the micro-channel; a viewing area associated with the micro-channel, the viewing area being configured to lie in an optical path of an imager when the cartridge is received by a blood analyzer; and a hemoglobin inspection area flow connected to the second reservoir, wherein the hemoglobin inspection area is configured to lie in an optical path of a light source when the cartridge is received by the blood analyzer. - View Dependent Claims (22, 23, 24, 25)
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Specification