FILAMENTARY DEVICES FOR TREATMENT OF VASCULAR DEFECTS

• US 20140358178A1
• Filed: 08/14/2014
• Published: 12/04/2014
• Est. Priority Date: 08/16/2013
• Status: Active Grant

• Current Assignee: Microvention Incorporated (Terumo Corporation)
• Original Assignee: Sequent Medical, Inc. (Terumo Corporation)
• Inventors: HEWITT, Todd J., MERRITT, Brian E., PATTERSON, William R.
• Granted Patent: US 9,078,658 B2
• Time in Patent Office: Days
• US Class Current: 606/200
• CPC Class Codes: A61B 17/12013 for use in minimally invasive surgery, e.g. endoscopic surgery
• CPC Class Codes: A61B 17/12031 complete occlusion
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12177 comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
• CPC Class Codes: A61B 2017/00539 hydraulically
• CPC Class Codes: A61B 2017/00778 Operations on blood vessels A61B2017/22097, A61B2017/320741 take precedence
• CPC Class Codes: A61B 2017/00867 shape memory effect
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12068 detachable by heat
• CPC Class Codes: A61B 2017/1209 detachable by electrical current or potential, e.g. electroactive polymer
• CPC Class Codes: A61B 2017/12095 Threaded connection
• CPC Class Codes: A61B 2090/3966 Radiopaque markers visible in an X-ray image

Abstract

Devices and methods for treatment of a patient'"'"'s vasculature with some embodiments configured for delivery with a microcatheter for treatment of the cerebral vasculature of a patient. Embodiments may include a self-expanding resilient permeable shell having a radially constrained elongated state configured for delivery within a catheter lumen, an expanded state with a globular and longitudinally shortened configuration relative to the radially constrained state, and a plurality of elongate filaments which are woven together, which define a cavity of the permeable shell Some embodiments may include at least about 40% composite filaments having a high strength material and a highly radiopaque material. In some embodiments, the total cross sectional area of the highly radiopaque material is between about 11% and about 30% of the total cross sectional area of the plurality of elongate elements.

Claims

1. A device for treatment of a patient'"'"'s vasculature, comprising:

a resilient self-expanding permeable shell including a radially constrained elongated state configured for delivery within a catheter lumen, an expanded state with a globular and longitudinally shortened configuration relative to the radially constrained state, and a plurality of elongate filaments which are woven together, which define a cavity of the permeable shell and which include at least about 40% composite filaments relative to a total number of filaments, the composite filaments comprising a high strength material and a highly radiopaque material.

2. The device of claim 1 wherein the plurality of elongate filaments are secured relative to each other at a distal end of the permeable shell.

3. The device of claim 1, wherein the plurality of elongate filaments are secured relative to each other at a proximal end of the permeable shell.

4. The device of claim 1, wherein the plurality of elongate filaments comprises about 50 to about 190 composite filaments.

5. The device of claim 4, wherein the plurality of elongate filaments comprises about 70 to about 150 composite filaments.

6. The device of claim 1, wherein the composite filaments comprise drawn filled tube wires.

7. The device of claim 6, wherein the drawn filled tube wires have a fill ratio of cross sectional area of between about 10% and about 50%.

8. The device of claim 7, wherein drawn filled tube wires have a fill ratio of cross sectional area of between about 20% and about 40%.

9. The device of claim 8, wherein drawn filled tube wires have a fill ratio of cross sectional area of between about 25% and about 35%.

10. The device of claim 1, wherein the highly radiopaque material of the composite filaments comprises tantalum.

11. The device of claim 1, wherein the highly radiopaque material of the composite filaments comprises platinum.

12. The device of claim 1, wherein the highly radiopaque material of the composite filaments comprises gold.

13. A device for treatment of a patient'"'"'s vasculature, comprising:

a resilient self-expanding permeable shell including a radially constrained elongated state configured for delivery within a catheter lumen, an expanded state with a globular and longitudinally shortened configuration relative to the radially constrained state, and a plurality of elongate filaments which are woven together, the plurality of filaments having a total cross sectional area and further defining a cavity of the permeable shell and which include at least some composite filaments, the composite filaments comprising a high strength material and a highly radiopaque material; and

wherein the total cross sectional area of the highly radiopaque material is between about 11% and about 30% of the total cross sectional area of the plurality of elongate elements.

14. The device of claim 13, wherein the total cross sectional area of the highly radiopaque material is between about 15% and about 30% of the total cross sectional area of the plurality of elongate elements.

15. The device of claim 14, wherein the total cross sectional area of the highly radiopaque material is between about 15% and about 22% of the total cross sectional area of the plurality of elongate elements.

16. The device of claim 14, wherein the total cross sectional area of the highly radiopaque material is between about 19% and about 30% of the total cross sectional area of the plurality of elongate elements.

17. The device of claim 13, wherein the total cross sectional area of the highly radiopaque material is between about 11% and about 18.5% of the total cross sectional area of the plurality of elongate elements.

18. The device of claim 13, wherein the plurality of elongate filaments are secured relative to each other at a distal end of the permeable shell.

19. The device of claim 13, wherein the plurality of elongate filaments are secured relative to each other at a proximal end of the permeable shell.

20. The device of claim 13, wherein the composite filaments comprise drawn filled tube wires.

21. The device of claim 20, wherein the drawn filled tube wires have a fill ratio of cross sectional area of between about 10% and about 50%.

22. The device of claim 21, wherein the drawn filled tube wires have a fill ratio of cross sectional area of between about 20% and about 40%.

23. The device of claim 22, wherein the drawn filled tube wires have a fill ratio of cross sectional area of between about 25% and about 35%.

24. The device of claim 13, wherein the highly radiopaque material comprises tantalum.

25. The device of claim 13, wherein the highly radiopaque material comprises platinum.

26. The device of claim 13, wherein the highly radiopaque material comprises gold.