INHIBITORS OF HISTONE DEMETHYLASES
2 Assignments
0 Petitions
Accused Products
Abstract
Compounds of the form
In which Q is selected from —CH═NR12, —W, —CH2NHR13, —CH═O and —CH(OR17)2 capable of modulating the activity of histone demethylases (HDMEs), which are useful for prevention and/or treatment of diseases in which genomic dysregulation is involved in the pathogenesis, such as e.g. cancer and formulations and methods of use of such compounds.
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Citations
20 Claims
- 1. A compound of the Formula (I)
- 2. A compound having the structure
- 3. A compound having the structure
- 4. A compound having the structure
Specification