Residual Signal Feedback-Based Control of an Implant

• US 20140371821A1
• Filed: 06/17/2014
• Published: 12/18/2014
• Est. Priority Date: 06/17/2013
• Status: Active Grant

• Current Assignee: Nyxoah SA
• Original Assignee: Nyxoah SA
• Inventors: Mashiach, Adi, Mueller, Carsten
• Granted Patent: US 9,248,302 B2
• Time in Patent Office: Days
• US Class Current: 607/60
• CPC Class Codes: A61B 17/30 Surgical pincettes without pivotal connectionsfor holding suture needles or materials A61B17/0483; wound clamps A61B17/08 ; hand-held gripping tools without pivotal connections in general B25B9/02
• CPC Class Codes: A61B 2560/0219 of externally powered implanted units
• CPC Class Codes: A61B 2562/16 Details of sensor housings or probes; Details of structural supports for sensors A61B2560/0462 takes precedence
• CPC Class Codes: A61B 2562/164 the sensor is mounted in or on a conformable substrate or carrier
• CPC Class Codes: A61B 2562/227 Sensors with electrical connectors
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/11 Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb for measuring pulse A61B5/02 ;A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721
• CPC Class Codes: A61B 5/113 occurring during breathing
• CPC Class Codes: A61B 5/389 Electromyography [EMG]
• CPC Class Codes: A61B 5/4519 Muscles A61B5/389, A61B5/224 take precedence
• CPC Class Codes: A61B 5/4818 Sleep apnoea
• CPC Class Codes: A61B 5/682 Mouth, e.g., oral cavity; tongue; Lips; Teeth
• CPC Class Codes: A61B 5/6822 Neck
• CPC Class Codes: A61B 5/6833 Adhesive patches
• CPC Class Codes: A61B 5/6876 Blood vessel
• CPC Class Codes: A61B 7/04 Electric stethoscopes microphones, acoustic transducers therefor H04R
• CPC Class Codes: A61F 5/566 Intra-oral devices
• CPC Class Codes: A61N 1/0404 for external use A61N1/06 takes precedence
• CPC Class Codes: A61N 1/0456 Specially adapted for transcutaneous electrical nerve stimulation [TENS]
• CPC Class Codes: A61N 1/0492 : Patch electrodes A61N1/0412, A61N1/0428 take precedence
• CPC Class Codes: A61N 1/0514 : Electrodes for the urinary tract
• CPC Class Codes: A61N 1/0526 : Head electrodes A61N1/0551 takes precedence
• CPC Class Codes: A61N 1/0553 : Paddle shaped electrodes, e.g. for laminotomy
• CPC Class Codes: A61N 1/36003 : of motor muscles, e.g. for walking assistance
• CPC Class Codes: A61N 1/3601 : of respiratory organs
• CPC Class Codes: A61N 1/36014 : External stimulators, e.g. with patch electrodes external pacemakers A61N1/3625
• CPC Class Codes: A61N 1/3605 : Implantable neurostimulators for stimulating central or peripheral nerve system
• CPC Class Codes: A61N 1/36057 : adapted for stimulating afferent nerves
• CPC Class Codes: A61N 1/36075 : Headache or migraine
• CPC Class Codes: A61N 1/3611 : Respiration control stimulating respiratory organs A61N1/3601
• CPC Class Codes: A61N 1/36117 : for treating hypertension
• CPC Class Codes: A61N 1/36135 : using physiological parameters
• CPC Class Codes: A61N 1/36139 : with automatic adjustment
• CPC Class Codes: A61N 1/36146 : specified by the stimulation parameters
• CPC Class Codes: A61N 1/37223 : Circuits for electromagnetic coupling
• CPC Class Codes: A61N 1/37229 : Shape or location of the implanted or external antenna
• CPC Class Codes: A61N 1/3756 : Casings with electrodes thereon, e.g. leadless stimulators
• CPC Class Codes: A61N 1/3758 : Packaging of the components within the casing
• CPC Class Codes: A61N 1/3787 : from an external energy source
• CPC Class Codes: A61N 2/006 : for magnetic stimulation of nerve tissue
• CPC Class Codes: A61N 2/02 : using magnetic fields produced by coils, including single turn loops or electromagnets A61N2/12 takes precedence
• CPC Class Codes: A61N 2001/37294 : Means for testing medical devices within the package prior to implantation

Abstract

A wireless feedback device for monitoring an implant unit configured for location in a body of a subject is provided. The device may include a flexible substrate configured for removable attachment to the subject'"'"'s skin, a primary antenna disposed on the flexible substrate, an interface configured to receive from the primary antenna a feedback signal based on wireless interaction with a secondary antenna associated with an implant unit configured to be located in the body of the subject, and at least one processing device. The at least one processing device may be configured detect a feedback signal on the primary antenna after cessation of a transmission to the secondary antenna, analyze the feedback signal to determine information relating to a function of the implant unit, and cause at least one response based on the analysis of the feedback signal.

Claims

1. A wireless feedback device for monitoring an implant unit configured for location in a body of a subject, the device comprising:

a flexible substrate configured for removable attachment to the subject'"'"'s skin;

a primary antenna disposed on the flexible substrate;

an interface configured to receive from the primary antenna a feedback signal based on wireless interaction with a secondary antenna associated with an implant unit configured to be located in the body of the subject; and

at least one processing device configured to;

cause application of a primary signal to the primary antenna such that the primary antenna begins wirelessly transmitting to the secondary antenna on the implant unit;

discontinue application of the primary signal to the primary antenna such that the primary antenna ceases wireless transmission to the secondary antenna;

detect the feedback signal on the primary antenna after cessation of transmission to the secondary antenna;

analyze the feedback signal to determine information relating to a function of the implant unit; and

cause at least one response based on the analysis of the feedback signal.

2. The device of claim 1, wherein the information includes at least one of power consumption, energy delivery, and implant functionality.

3. The device of claim 1, wherein the processor is configured to conduct a diagnostic test on the implant based on the feedback signal.

4. The device of claim 1, wherein the processor is further configured to monitor the primary signal transmitted by the primary antenna to achieve constant current delivery in the implant, based on the feedback signal.

5. The device of claim 1, wherein the processor is further configured to determine an optimal treatment level based on the feedback signal.

6. The device of claim 1, wherein the at least one response includes an indication to a user of whether the implant unit is functioning properly.

7. The device of claim 1, wherein the at least one response includes an adjustment to at least one attribute of the primary signal and application of the adjusted primary signal to the primary antenna.

8. The device of claim 7, wherein the at least one attribute includes an amplitude of the primary signal.

9. The device of claim 1, wherein the at least one response includes an automatic determination of an adjusted current level for the primary signal and application of the adjusted primary signal to the primary antenna.