METHODS AND SYSTEMS FOR ADAPTIVE ADJUSTMENT OF VENTILATOR SETTINGS
First Claim
1. A method for ventilating a patient with a ventilator comprising:
- receiving a plurality of ventilator parameters;
estimating a net value of patient muscle effort based on the received ventilator parameters, wherein the net value of patient muscle effort is estimated using a parameter estimate vector update equation to solve for a recursive least squares gain value representing the estimated net value of patient effort at a time instance by subtracting a squared gain value for a previous time instance multiplied by a regression parameter vector at the time instance and a transpose of the regression parameter vector at the time instance and a transpose of the squared gain value for the previous time instance divided the result by one plus the transpose of the regression parameter vector at the time instance multiplied by the squared gain value for the previous time instance multiplied by the regression parameter vector at the time instance from the gain value for the previous time instance; and
calculating target inspiratory pressure based on the estimated net value of patient effort.
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Abstract
This disclosure describes systems and methods for providing optimized adjustment of a ventilator based on an estimated net value of patient effort. The disclosure describes a novel breath type that delivers a target airway pressure calculated based on an estimated patient muscle effort. A net value of patient muscle effort is estimated using a parameter estimate vector update equation to solve for a recursive least squares gain value representing the estimated net value of patient effort. The estimated net value of patient muscle effort is used to determine a target airway pressure, which is then used to determine a target inspiratory pressure to be delivered to a patient. The target inspiratory pressure is used to determine an onset and/or end of a ventilation cycle and therefore improves the synchronization between the ventilator and the patient.
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Citations
20 Claims
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1. A method for ventilating a patient with a ventilator comprising:
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receiving a plurality of ventilator parameters; estimating a net value of patient muscle effort based on the received ventilator parameters, wherein the net value of patient muscle effort is estimated using a parameter estimate vector update equation to solve for a recursive least squares gain value representing the estimated net value of patient effort at a time instance by subtracting a squared gain value for a previous time instance multiplied by a regression parameter vector at the time instance and a transpose of the regression parameter vector at the time instance and a transpose of the squared gain value for the previous time instance divided the result by one plus the transpose of the regression parameter vector at the time instance multiplied by the squared gain value for the previous time instance multiplied by the regression parameter vector at the time instance from the gain value for the previous time instance; and calculating target inspiratory pressure based on the estimated net value of patient effort. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A ventilator system comprising:
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a pressure generating system adapted to generate a flow of breathing gas; a ventilation tubing system including a patient interface for connecting the pressure generating system to a patient; one or more sensors operatively coupled to at least one of the pressure generating system, the patient, and the ventilation tubing system, wherein the one or more sensors generate output indicative of an inspiration flow; an adaptive calculation module adapted to perform quantification of patient muscle by establishing a respiratory predictive model of the ventilator based on an equation of motion and received raw measurement parameter data or estimated ventilator parameters and extracting an estimated net value of patient muscle effort by solving for a recursive least squares gain value representing the estimated net value of patient muscle effort at a time instance by subtracting a squared gain value for a previous time instance multiplied by a regression parameter vector at the time instance and a transpose of the regression parameter vector at the time instance and a transpose of the squared gain value for the previous time instance divided the result by one plus the transpose of the regression parameter vector at the time instance multiplied by the squared gain value for the previous time instance multiplied by the regression parameter vector at the time instance from the gain value for the previous time instance; and a support module operable to adjust a target inspiratory pressure based on the estimated net value of patient muscle effort or one or more other respiratory parameters derived based on the estimated net value of patient muscle effort. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16, 17)
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18. A computer-readable medium having computer-executable instructions for performing a method of ventilating a patient with a ventilator, the method comprising:
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receiving a plurality of ventilator parameters; estimating a net value of patient muscle effort based on the received ventilator parameters, wherein the net value of patient muscle effort is estimated using a parameter estimate vector update equation to solve for a recursive least squares gain value representing the estimated net value of patient muscle effort at a time instance by subtracting a squared gain value for a previous time instance multiplied by a regression parameter vector at the time instance and a transpose of the regression parameter vector at the time instance divided the result by one plus a gain value for the previous time instance multiplied by the transpose of the regression parameter vector at the time instance multiplied by the regression parameter vector at the time instance from the gain value for the previous time instance; calculating target inspiratory pressure based on the estimated net value of patient muscle effort; and sending the target inspiratory pressure to a ventilator component to optimally adjust a delivered target airway pressure based on the target inspiratory pressure. - View Dependent Claims (19, 20)
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Specification