TISSUE TO END TIDAL CO2 MONITOR

• US 20150005591A1
• Filed: 01/30/2013
• Published: 01/01/2015
• Est. Priority Date: 01/31/2012
• Status: Abandoned Application

• Current Assignee: Regents of the University of California (University of California)
• Original Assignee: Regents of the University of California (University of California)
• Inventors: Davis, Daniel
• Application Number:
  US14/376,122
• Publication Number:
  US 20150005591A1
• Time in Patent Office: Days
• US Class Current: 600/301
• CPC Class Codes: A61B 5/0836 Measuring rate of CO2 production
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/1477 non-invasive
• CPC Class Codes: A61B 5/6815 Ear
• CPC Class Codes: A61B 5/6819 Nose
• CPC Class Codes: A61B 5/682 Mouth, e.g., oral cavity; tongue; Lips; Teeth
• CPC Class Codes: A61B 5/7278 Artificial waveform generation or derivation, e.g. synthesising signals from measured signals A61B5/327 takes precedence
• CPC Class Codes: A61B 5/7282 Event detection, e.g. detecting unique waveforms indicative of a medical condition A61B5/4094, A61B5/4818, A61B5/349, A61B5/0823 take precedence
• CPC Class Codes: A61B 5/743 Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots

Abstract

A method comprises measuring tissue carbon dioxide levels of a living organism, measuring end-tidal carbon dioxide levels of the living organism; and calculating at least one tissue-to-end-tidal carbon dioxide gradient value based on the measured tissue carbon dioxide levels and the measured end-tidal carbon dioxide levels, the tissue-to-end-tidal carbon dioxide gradient value being indicative of a measure of perfusion of the living organism.

Claims

1. A method, comprising:

measuring tissue carbon dioxide levels of a living organism;

measuring end-tidal carbon dioxide levels of the living organism; and

calculating at least one tissue-to-end-tidal carbon dioxide gradient value based on the measured tissue carbon dioxide levels and the measured end-tidal carbon dioxide levels, the tissue-to-end-tidal carbon dioxide gradient value being indicative of a measure of perfusion of the living organism.

2. The method of claim 1, wherein the measurement of the tissue carbon dioxide levels is non-invasive and performed in at least one of:

a buccal mucosa region of the living organism, a sublingual region of the living organism, a nasal septum region of the living organism, and an ear concha region of the living organism.

3. The method of claim 1, wherein the measurement of the end-tidal carbon dioxide levels is non-invasive and performed in at least one of:

an endotracheal tube attached to the living organism, nostrils of the living organism, and a mouth of the living organism.

4. The method of claim 1, wherein the non-invasive measurement of the end-tidal carbon dioxide levels is performed via a capnometer.

5. The method of claim 1, wherein the non-invasive measurement of the tissue carbon dioxide levels is performed via a pulse oximeter.

6. The method of claim 1, further comprising:

performing post-processing on the tissue-to-end-tidal carbon dioxide gradient value.

7. The method of claim 1, the measure of perfusion being indicative of a level of shock experienced by the organism.

9. The system of claim 6, wherein the first sensor comprises a capnometer.

10. The system of claim 6, wherein the second sensor comprises a pulse oximeter.

11. The system of claim 6, wherein the at least one memory and the computer program code are further configured to, with the at least one processor, cause the calculating apparatus to perform post-processing on the tissue-to-end-tidal carbon dioxide gradient value.

12. The system of claim 6, the measure of perfusion being indicative of a level of shock experienced by the organism.

8. A system, comprising:

at least a first sensor configured to non-invasively measure tissue carbon dioxide levels in a human being;

at least a second sensor configured to non-invasively measure end-tidal carbon dioxide levels in the human being; and

a calculating apparatus comprising at least one processor and at least one memory including computer program code, the at least one memory and the computer program code configured to, with the at least one processor, cause the calculating apparatus to calculate at least one tissue-to-end-tidal carbon dioxide gradient value based on the measured tissue carbon dioxide levels and the measured end-tidal carbon dioxide levels, the tissue-to-end-tidal carbon dioxide gradient value being indicative of a level of perfusion of the living organism.