ELECTRICAL DETERMINATION OF THE LOCAL PHYSIOLOGICAL ENVIRONMENT IN SPINAL CORD STIMULATION

• US 20150005846A1
• Filed: 06/23/2014
• Published: 01/01/2015
• Est. Priority Date: 07/01/2013
• Status: Abandoned Application

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Ranu, Emarit A.S., Zhu, Changfang, Lee, Dongchul, Hershey, Bradley L.
• Application Number:
  US14/312,426
• Publication Number:
  US 20150005846A1
• Time in Patent Office: Days
• US Class Current: 607/59
• CPC Class Codes: A61N 1/36128 Control systems
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance
• CPC Class Codes: A61N 1/37258 Alerting the patient
• CPC Class Codes: A61N 1/3787 from an external energy source

Abstract

A medical system configured for performing a medical function in a patient comprises a medical lead configured for being implanted adjacent a tissue region of the patient, and an electrode configured for being implanted adjacent the tissue region. The medical system further comprises analog output circuitry configured for delivering one or more electrical signals having a plurality of different sinusoidal frequency components to the tissue region via the electrode, monitoring circuitry configured for measuring a plurality of different frequency-dependent or other basis function electrical parameter values in response to the delivery of the one or more electrical signals to the tissue region, and at least one controller/processor configured for analyzing the different electrical parameter values, and performing a function based on the different analyzed electrical parameter values.

Claims

1. A medical system configured for performing a medical function in a patient, comprising:

a medical lead configured for being implanted adjacent a tissue region of the patient;

an electrode configured for being implanted adjacent the tissue region;

analog output circuitry configured for delivering one or more electrical signals having a plurality of different sinusoidal frequency components to the tissue region via the electrode;

monitoring circuitry configured for measuring a plurality of different frequency-dependent electrical parameter values in response to the delivery of the one or more electrical signals to the tissue region; and

at least one controller/processor configured for analyzing the different electrical parameter values, and performing a function based on the different analyzed electrical parameter values.

2. The medical system of claim 1, wherein the electrode is carried by the medical lead.

3. The medical system of claim 1, wherein the monitoring circuitry is configured for measuring the different parameter values at the electrode.

4. The medical system of claim 1, wherein the electrical parameter values are impedance values.

5. The medical system of claim 1, wherein the one or more electrical signals comprises at least one monopolar electrical signal and at least one multipole electrical signal, the electrical parameter values comprise a plurality of monopolar impedance values and a plurality of multipolar impedance values, and the controller/processor is configured for analyzing the electrical parameter values by computing differences between the monopolar impedance values and the multipolar impedance values.

6. The medical system of claim 1, wherein the electrical parameter values are one or both of a resistance and a reactance.

7. The medical system of claim 1, wherein the one or more electrical signals comprises a single electrical signal, and the monitoring circuitry includes a signal decomposition analyzer configured for measuring the electrical parameter values using any specific basis function or functions.

8. The medical system of claim 7, wherein the signal decomposition analyzer is a frequency spectrum analyzer configured for measuring the electrical parameter values at frequencies corresponding to the different sinusoidal frequency components.

9. The medical system of claim 7, wherein the single electrical signal comprises an electrical pulse train.

10. The medical system of claim 1, wherein the one or more electrical signals comprises a plurality of different electrical signals having different frequency component profiles, and the monitoring circuitry is configured for measuring the electrical parameter values respectively in response to the delivery of the different electrical signals to the tissue region.

11. The medical system of claim 10, wherein the plurality of electrical signals comprises a plurality of electrical pulse trains having different pulse rates and/or different pulse widths.

12. The medical system of claim 10, wherein the plurality of electrical signals comprises a plurality of sinusoidal signals having different frequencies.

13. The medical system of claim 1, wherein the function is determining a migration of the medical lead.

14. The medical system of claim 1, wherein the function is determining a state of an encapsulation process with respect to the medical lead.

15. The medical system of claim 1, wherein the function is determining a posture and/or physical activity of the patient.

16. The medical system of claim 1, wherein the function is a corrective action.

17. The medical system of claim 16, wherein the medical lead carries at least one electrode, the analog output circuitry is configured for delivering therapeutic electrical energy to the electrode, the at least one controller/processor is configured for programming the at least one electrode with a set of neuromodulation parameters prior to performing the function, and the corrective action is modifying the neuromodulation parameter set and reprogramming the at least one electrode with the modified neuromodulation parameter set.

18. The medical system of claim 16, wherein the corrective action is providing a notification message or warning to a user.

19. The medical system of claim 1, further comprising memory storing at least one reference value, wherein the at least one controller/processor is configured for analyzing the electrical parameter values by comparing the electrical parameter values to the at least one reference value, and performing the function based on the comparison.

20. The medical system of claim 1, further comprising an implantable casing containing the analog output circuitry, monitoring circuitry, and the controller/processor.

21. The medical system of claim 1, further comprising an external control device containing the at least one controller/processor.