SWALLOWABLE DRUG DELIVERY DEVICE AND METHOD OF DELIVERY
First Claim
1. A method for delivering a therapeutic agent into the wall of the small intestine, the method comprising:
- swallowing a drug delivery device comprising a capsule, an expandable member and a tissue penetrating therapeutic agent for; and
expanding the expandable member responsive to a condition in the small intestine to deliver the therapeutic agent into the intestinal wall of the small intestine.
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Accused Products
Abstract
Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Some embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. The device comprises a capsule sized to be swallowed and pass through the intestinal tract. The capsule can include at least one guide tube, one or more tissue penetrating members positioned in the guide tube, a delivery member, an actuating mechanism and a release element. The release element degrades upon exposure to various conditions in the intestine so as to release and actuate the actuating mechanism. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.
110 Citations
9 Claims
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1. A method for delivering a therapeutic agent into the wall of the small intestine, the method comprising:
- swallowing a drug delivery device comprising a capsule, an expandable member and a tissue penetrating therapeutic agent for; and
expanding the expandable member responsive to a condition in the small intestine to deliver the therapeutic agent into the intestinal wall of the small intestine. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
- swallowing a drug delivery device comprising a capsule, an expandable member and a tissue penetrating therapeutic agent for; and
Specification