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GENERATION OF ANTIBODIES TO TUMOR ANTIGENS AND GENERATION OF TUMOR SPECIFIC COMPLEMENT DEPENDENT CYTOTOXICITY BY ADMINISTRATION OF ONCOLYTIC VACCINIA VIRUS

  • US 20150037355A1
  • Filed: 01/04/2012
  • Published: 02/05/2015
  • Est. Priority Date: 01/04/2011
  • Status: Active Grant
First Claim
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1. A method of inducing tumor-specific antibody mediated complement-dependent cytotoxic response in an animal having a tumor comprising administering to said animal a composition comprising a replication competent oncolytic virus wherein administration of said composition induces antibodies in said animal that mediate a CDC response specific to said tumor.

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