TISSUE SCAFFOLD

• US 20150037884A1
• Filed: 10/21/2014
• Published: 02/05/2015
• Est. Priority Date: 05/11/2004
• Status: Abandoned Application

• Current Assignee: Synthasome, Inc.
• Original Assignee: Synthasome, Inc.
• Inventors: Ratcliffe, Anthony, Kern, Andreas, Ratcliffe, Fatemeh
• Application Number:
  US14/519,328
• Publication Number:
  US 20150037884A1
• Time in Patent Office: Days
• US Class Current: 435/366
• CPC Class Codes: A61L 2300/406 Antibiotics
• CPC Class Codes: A61L 2300/414 Growth factors
• CPC Class Codes: A61L 2300/602 Type of release, e.g. controlled, sustained, slow
• CPC Class Codes: A61L 27/3633 Extracellular matrix [ECM]
• CPC Class Codes: A61L 27/38 containing added animal cells organs or tissue containing native cells A61L27/36
• CPC Class Codes: A61L 27/54 Biologically active materials, e.g. therapeutic substances A61L27/227 takes precedence
• CPC Class Codes: A61L 27/58 Materials at least partially resorbable by the body
• CPC Class Codes: C12N 2513/00 3D culture
• CPC Class Codes: C12N 2533/40 Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
• CPC Class Codes: C12N 5/0656 Adult fibroblasts

Abstract

A tissue engineered construct made totally or in part from biocompatible materials and mammalian cells and/or cell products is provided. These constructs are useful in regenerating complex tissues such as bone, ligament and tendon, which may fabricated into medical devices suitable for use in the treatment of injuries and maladies such as rotator cuff injuries, periodontal disease and hernia.

Claims

1. A three-dimensional tissue comprising a biocompatible scaffold, a bioabsorbable material encasing or layered with the scaffold, and an extracellular matrix.