FLUID PUMPING SYSTEMS, DEVICES AND METHODS

• US 20150050166A1
• Filed: 10/27/2014
• Published: 02/19/2015
• Est. Priority Date: 04/14/2006
• Status: Active Grant

• Current Assignee: Deka Products Limited Partnership
• Original Assignee: Deka Products Limited Partnership
• Inventors: Tracey, Brian D., Gray, Larry B., Demers, Jason A., Dale, James D., Perry, N. Christopher, Wilt, Michael J.
• Granted Patent: US 10,302,075 B2
• Time in Patent Office: Days
• US Class Current: 417/395
• CPC Class Codes: A61F 2007/126 for invasive application, e.g. for introducing into blood vessels
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1605 Physical characteristics of the dialysate fluid
• CPC Class Codes: A61M 1/1656 Apparatus for preparing dialysates
• CPC Class Codes: A61M 1/287 Dialysates therefor
• CPC Class Codes: A61M 1/362227 the interface providing means for actuating on functional elements of the cassette, e.g. plungers
• CPC Class Codes: A61M 1/36225 with blood pumping means or components thereof
• CPC Class Codes: A61M 1/362263 Details of incorporated filters
• CPC Class Codes: A61M 1/362265 Details of valves
• CPC Class Codes: A61M 1/3626 Gas bubble detectors
• CPC Class Codes: A61M 1/369 Temperature treatment
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2205/127 with provisions for heating or cooling
• CPC Class Codes: A61M 2205/128 with incorporated valves
• CPC Class Codes: A61M 2205/3317 Electromagnetic, inductive or dielectric measuring means
• CPC Class Codes: A61M 2205/3324 PH measuring means
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 2205/3606 cooled
• CPC Class Codes: A61M 2205/3653 by Joule effect, i.e. electric resistance
• CPC Class Codes: A61M 2205/502 : User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 60/113 : in other functional devices, e.g. dialysers or heart-lung machines
• CPC Class Codes: A61M 60/36 : for specific blood treatment; for specific therapy
• CPC Class Codes: A61M 60/43 : using vacuum at the blood pump, e.g. to accelerate filling
• CPC Class Codes: A61M 60/554 : of blood pressure
• CPC Class Codes: A61M 60/837 : Aspects of flexible displacement members, e.g. shapes or materials
• CPC Class Codes: A61M 60/847 : arranged in a cassette
• CPC Class Codes: A61M 60/849 : Disposable parts
• CPC Class Codes: A61M 60/851 : Valves
• CPC Class Codes: A61M 60/892 : Active valves, i.e. actuated by an external force
• CPC Class Codes: A61M 60/894 : Passive valves, i.e. valves actuated by the blood
• CPC Class Codes: F04B 23/06 : the pumps being all of reciprocating positive-displacement type
• CPC Class Codes: F04B 39/12 : Casings; Cylinders; Cylinder heads; Fluid connections
• CPC Class Codes: F04B 39/123 : Fluid connections
• CPC Class Codes: F04B 39/14 : Provisions for readily assembling or disassembling
• CPC Class Codes: F04B 43/0081 : systems, control, safety measures
• CPC Class Codes: F04B 43/073 : the actuating fluid being controlled by at least one valve
• CPC Class Codes: F04B 43/0736 : with two or more pumping chambers in parallel
• CPC Class Codes: F04B 53/16 : Casings; Cylinders; Cylinder liners or heads; Fluid connections
• CPC Class Codes: F04B 53/22 : Arrangements for enabling ready assembly or disassembly
• CPC Class Codes: F04B 7/02 : the valving being fluid-actuated
• CPC Class Codes: G01K 1/08 : Protective devices, e.g. casings
• CPC Class Codes: G01K 1/16 : Special arrangements for conducting heat from the object to the sensitive element
• CPC Class Codes: G01M 3/188 : for radiators
• CPC Class Codes: G05D 7/0682 : using a plurality of flow sources
• CPC Class Codes: Y02A 90/10 : Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

Embodiments of the present invention relate generally to certain types of reciprocating positive-displacement pumps (which may be referred to hereinafter as “pods,” “pump pods,” or “pod pumps”) used to pump fluids, such as a biological fluid (e.g., blood or peritoneal fluid), a therapeutic fluid (e.g., a medication solution), or a surfactant fluid. The pumps may be configured specifically to impart low shear forces and low turbulence on the fluid as the fluid is pumped from an inlet to an outlet. Such pumps may be particularly useful in pumping fluids that may be damaged by such shear forces (e.g., blood, and particularly heated blood, which is prone to hemolysis) or turbulence (e.g., surfectants or other fluids that may foam or otherwise be damaged or become unstable in the presence of turbulence).

Claims

1-82. -82. (canceled)

83. A flexible diaphragm for use in a reciprocating positive-displacement pump, the diaphragm configured to be interposed between a pumping chamber of the pump and a control chamber of the pump, and having a pre-formed hemispheroid membrane having a pumping chamber side and an opposing control chamber side;

wherein the diaphragm comprises a plurality of raised elements on the pumping chamber side of the membrane.

86. A flexible diaphragm according to claim 83, wherein the raised elements comprise raised bumps, dots, bars, ribs, or rings.

87. A flexible diaphragm according to claim 86, wherein the diaphragm comprises a circular rim attached to or formed with a peripheral portion of the membrane.

88. A flexible diaphragm according to claim 87, wherein the rim is adapted for interconnection with at least one of a pumping chamber wall and an actuation chamber wall.

89. A diaphragm according to claim 87 or 88, wherein the rim and the membrane are made from silicone.

90. A diaphragm according to claim 89, wherein the rim and the membrane are made from high-elongation silicone.

99. A flexible diaphragm according to claim 83, wherein the diaphragm is substantially dome-shaped.

100. A flexible diaphragm according to claim 83, wherein the membrane has a variable thickness.

101. A flexible diaphragm according to claim 88, wherein the rim is configured to be fastened between first and second mating rigid components of the pump, the first rigid component of the pump comprising a pumping chamber plate, and the second rigid component of the pump comprising a control chamber plate.

84-85. -85. (canceled)

91-98. -98. (canceled)

102. A reciprocating positive displacement pump having a variable volume pumping chamber and variable volume control chamber comprising:

a rigid pumping chamber wall separated from a rigid control chamber wall by a flexible diaphragm;

the rigid pumping chamber wall comprising a fluid inlet and a fluid outlet;

the rigid control chamber wall comprising a control port for ingress and egress of a control fluid;

the flexible diaphragm having a pre-formed hemispheroid membrane having a pumping chamber side and an opposing control chamber side;

wherein the diaphragm comprises a plurality of raised elements on the pumping chamber side of the membrane, so that the membrane is prevented from fully contacting the pumping chamber wall when a control fluid is infused into the control chamber.

103. A reciprocating positive displacement pump according to claim 102, wherein the raised elements comprise raised bumps, dots, bars, or rings.

104. A reciprocating positive displacement pump according to claim 103, wherein the diaphragm comprises a circular rim attached to or formed with a peripheral portion of the membrane.

105. A reciprocating positive displacement pump according to claim 104, wherein the rim is adapted for interconnection with the pumping chamber wall or the actuation chamber wall.

106. A reciprocating positive displacement pump according to claim 104, wherein the rim is configured to be fastened between mating components of the pumping chamber wall and the control chamber wall.

107. A reciprocating positive displacement pump according to claim 105, wherein the mating components comprise grooves in which the rim is positioned.

108. A reciprocating positive displacement pump according to claim 102, wherein the diaphragm is substantially dome-shaped.

109. A reciprocating positive displacement pump according to claim 102, wherein the membrane has a variable thickness.

110. A pump cassette comprising:

a pumping chamber plate spaced apart from an actuation chamber plate by a mid-plate;

the pumping chamber plate having a pumping chamber housing portion in fluid communication with a fluid path formed in the pumping chamber plate;

the actuation chamber plate having a control chamber housing portion that includes a pump actuation port configured to convey an actuation fluid to or from the control chamber housing portion;

the mid-plate configured to hold a pump diaphragm having a pre-formed hemispheroid membrane having a pumping chamber side and an opposing control chamber side, the pumping chamber side of the membrane comprising a plurality of raised elements;

wherein the pumping chamber plate, the mid-plate and the actuation plate are joined together, the pump diaphragm fluidically sealing the pumping chamber housing portion from the control chamber housing portion.

111. A pump cassette according to claim 110, wherein the actuation plate comprises a valve actuation housing portion that includes a valve actuation port configured to convey the actuation fluid to or from the valve actuation housing portion, wherein the mid-plate is configured to hold a valve diaphragm separating the valve actuation housing portion from a fluidic valve chamber portion of the pumping chamber plate, and wherein the fluidic valve chamber portion of the pumping chamber plate is in fluid communication with the pumping chamber housing portion via the fluid path.

112. A pump cassette according to claim 111, wherein the actuation ports are configured to connect or attach to a base station for conveying actuation fluid to or from the actuation ports, so that the base station may convey actuation fluid to or from the pump actuation port independently of the valve actuation port.

113. A pump cassette according to claim 110 or 111, wherein the actuation fluid comprises a gas or air.

114. A pump cassette according to claim 110, wherein the diaphragm is pre-formed so that at least a portion of the diaphragm is dome-shaped.