COMBINATION THERAPY FOR TREATING CANCER
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Accused Products
Abstract
The present invention relates to compositions comprising inhibitors of human histone methyltransferase EZH2 and one or more other therapeutic agents, particularly anticancer agents such as prednisone, and methods of combination therapy for administering to subjects in need thereof for the treatment of cancer.
23 Citations
35 Claims
- 1. A composition comprising a compound of Formula (IIa):
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2. A composition comprising any one of the compounds listed in Table 1 or pharmaceutically acceptable salts thereof and one or more other therapeutic agents.
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9-11. -11. (canceled)
- 12. A method of treating or preventing cancer comprising administering to a subject in need thereof a therapeutically effective dose of a compound of Formula (IIa):
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19-22. -22. (canceled)
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25-27. -27. (canceled)
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29-32. -32. (canceled)
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35-37. -37. (canceled)
Specification