PHARMACEUTICAL INJECTION DEVICE

• US 20150051538A1
• Filed: 11/09/2012
• Published: 02/19/2015
• Est. Priority Date: 11/10/2011
• Status: Active Grant

• Current Assignee: PHC Holdings Corporation
• Original Assignee: Panasonic Healthcare Company Limited (PHC Holdings Corporation)
• Inventors: Hata, Shinsuke, Kondoh, Tsuguhiro, Kikuchi, Seiji, Ilo, Toshiaki, Nakajima, Yukio
• Granted Patent: US 9,289,551 B2
• Time in Patent Office: Days
• US Class Current: 604/67
• CPC Class Codes: A61M 2005/2006 Having specific accessories
• CPC Class Codes: A61M 2005/3123 having air entrapping or venting means, e.g. purging channels in pistons
• CPC Class Codes: A61M 2005/31588 electrically driven
• CPC Class Codes: A61M 2205/14 Detection of the presence or absence of a tube, a connector or a container in an apparatus
• CPC Class Codes: A61M 2205/215 Tilt detection, e.g. for warning or shut-off
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 5/1409 in series, e.g. first substance passing through container holding second substance, e.g. reconstitution systems needle sets A61M5/162
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: A61M 5/20 Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/2066 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/5086 for indicating if defective, used, tampered with or unsterile

Abstract

This pharmaceutical injection device comprises a main body case; a pharmaceutical syringe mounting portion provided inside the main body case; a piston that is provided so as to be movable with respect to a pharmaceutical syringe that is removably attached to the pharmaceutical syringe mounting portion; a drive mechanism for driving the piston; a controller that is electrically connected to the drive mechanism; and an acceleration sensor that is connected to the controller. When a manual mixing mode of the pharmaceutical syringe is selected, the controller changes to the next step (air venting mode) if the inclination angle of the main body case sensed by the acceleration sensor is greater than a specific value.

Claims

1. A pharmaceutical injection device, comprising:

a main body case including an opening;

an injection needle configured to be inserted and retracted through the opening;

a pharmaceutical syringe mounting portion provided inside the main body case;

a pharmaceutical syringe mounted to the pharmaceutical syringe mounting portion;

a piston movable in respect to the pharmaceutical syringe;

a drive mechanism configured to drive the piston;

an orientation sensor configured to sense an inclination angle of the main body case;

a controller electrically connected to the drive mechanism and the orientation sensor, the controller configured to execute a plurality of modes in a sequence,

the plurality of modes including a manual mixing mode;

wherein when the manual mixing mode is selected, the controller is configured to change the mode to a next mode when the inclination angle is greater than a specific value.

2. The pharmaceutical injection device according to claim 1, wherein

when the manual mixing mode is selected, the controller is further configured to count a number of times that the inclination angle has been greater than a threshold angle, and

the controller changes the mode to the next mode if the number of times is greater than or equal to a threshold number of times.

3. The pharmaceutical injection device according to claim 1, wherein:

the orientation sensor includes an acceleration sensor configured to sense an acceleration, and the inclination angle, of the main body case when manual mixing mode is selected.

4. The pharmaceutical injection device according to claim 3, further comprising:

a display section connected to the controller;

wherein the controller causes the display section to display a message prompting the user to minimize shaking of the main body case when the acceleration sensed by the acceleration sensor is greater than a threshold acceleration.

5. The pharmaceutical injection device according to claim 1, wherein:

the pharmaceutical syringe includes;

a cylinder,

a distal end gasket provided on a distal end side inside the cylinder,

a push-in gasket provided on a rear end side inside the cylinder,

a separation gasket provided between the distal end gasket and the push-in gasket,

a solid pharmaceutical contained inside the cylinder between the distal end gasket and the separation gasket,

a liquid pharmaceutical contained inside the cylinder between the push-in gasket and the separation gasket, and

a bypass that protrudes in an outer peripheral direction of the cylinder at a portion of the cylinder between the distal end gasket and the separation gasket.

6. The pharmaceutical injection device according to claim 1, wherein:

the controller changes the mode to the manual mixing mode after performing an automatic dissolution operation.,

the automatic dissolution operation including mixing and dissolving two pharmaceuticals housed in the pharmaceutical syringe.

7. The pharmaceutical injection device according to claim 1, wherein:

the controller changes the mode to the manual mixing mode prior to a pharmaceutical injection operation.

12. The pharmaceutical injection device according to claim 2, wherein:

the orientation sensor includes an acceleration sensor configured to sense an acceleration, and the inclination angle, of the main body case when manual mixing mode is selected.

13. The pharmaceutical injection device according to claim 1, wherein:

the next mode is an air venting mode.

14. The pharmaceutical injection device according to claim 1, wherein:

the controller is configured to change the mode to the manual mixing mode more than once after performing an automatic dissolution operation and prior to an pharmaceutical injection operation.

8. A pharmaceutical injection device, comprising:

a main body case including an opening;

an injection needle configured to be inserted and retracted through the opening;

a pharmaceutical syringe mounting portion provided inside the main body case;

a pharmaceutical syringe mounted to the pharmaceutical syringe mounting portion;

a piston movable in respect to the pharmaceutical syringe;

a drive mechanism configured to drive the piston;

an acceleration sensor configured to sense at least one of a vibration and an impact imparted to the main body case; and

a controller electrically connected to the drive mechanism and the acceleration sensor, the controller configured to determine that a malfunction has occurred when the acceleration accompanying vibration or impact to the main body case is greater than a specific value.

9. The pharmaceutical injection device according to claim 8, wherein:

the controller is further configured to determine if a malfunction has occurred during a pharmaceutical injection operation, and

to perform emergency shutdown of the drive mechanism when a malfunction has occurred during a pharmaceutical injection operation.

10. The pharmaceutical injection device according to claim 9, wherein:

the controller drives the drive mechanism to retract the injection needle after the emergency shutdown.

11. The pharmaceutical injection device according to any of claim 9, further comprising:

a display section connected to the controller;

wherein the controller causes the display section to display a caution when it is determined that a malfunction has occurred during the pharmaceutical injection operation.