CASSETTE ASSEMBLY FOR SYRINGE FILL SYSTEM

• US 20150053306A1
• Filed: 06/06/2014
• Published: 02/26/2015
• Est. Priority Date: 08/20/2013
• Status: Active Grant

• Current Assignee: Anutra Medical Inc.
• Original Assignee: Infusion Medical, Inc.
• Inventors: Davidian, Daniel K., Newnam, Scott G., Nichols, Eli B., Mosler, Theodore J.
• Granted Patent: US 9,393,177 B2
• Time in Patent Office: Days
• US Class Current: 141/2
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2055 having gripping means
• CPC Class Codes: A61J 1/2075 for external venting
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61J 1/22 with means for metering the amount of fluid
• CPC Class Codes: A61M 2202/048 Anaesthetics
• CPC Class Codes: A61M 2205/75 with filters
• CPC Class Codes: A61M 5/001 Apparatus specially adapted for cleaning or sterilising syringes or needles
• CPC Class Codes: A61M 5/1782 Devices aiding filling of syringes in situ combination of a vial and a syringe for transferring or mixing their contents A61J1/2096, filling of medical containers in general B65B3/003
• CPC Class Codes: A61M 5/2425 by compression of deformable ampoule or carpule wall
• CPC Class Codes: A61M 5/2448 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/3137 Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
• CPC Class Codes: A61M 5/31586 performed by rotationally moving or pivoted actuator, e.g. an injection lever or handle
• CPC Class Codes: A61M 5/31591 Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
• CPC Class Codes: A61M 5/31593 Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
• CPC Class Codes: A61M 5/502 for blocking the piston

Abstract

A syringe fill system is described, which is useful for filling syringes for dental anesthetic applications. The system incorporates capability for “push-pull”, “pull-push”, “push-push”, and “pull-pull” modes of operation, for loading syringes with compositions comprising multiple fluid components. A syringe fillable by such syringe fill systems is described, providing haptic and audible feedback to a user, to aid in administering precise amounts of therapeutic compositions. Also disclosed are cassette assemblies for use in such syringe fill systems. Such cassette assemblies may be formed of plastic and elastomeric materials of construction, as disposable or single-use components of the syringe fill system.

Claims

1. A cassette assembly, comprising:

a base manifold member including an interior manifold flow passage;

multiple fluid feed inlets extending outwardly from the base manifold member and communicating with the interior manifold flow passage via inlet passages containing check valves, the multiple inlets being configured for engagement with respective fluid supply packages; and

a syringe coupling mounted on the base manifold member, in fluid flow communication with the interior manifold flow passage to deliver fluid from the interior manifold flow passage to a syringe when coupled to the syringe coupling.

2. The cassette assembly of claim 1, adapted for push-pull dispensing of fluids from respective first and second fluid containers when engaged with respective ones of said inlet passages.

3. The cassette assembly of claim 2, wherein the check valves in the respective inlet passages have different crack pressures.

4. The cassette assembly of claim 3, wherein the check valve for push dispensing of fluid from the first fluid container has a crack pressure that is in a range of from 6 to 20 psi, and the check valve for pull dispensing of fluid from the second fluid container has a crack pressure that is in a range of from 0.5 to 10 psi, with the proviso that the crack pressure of the check valve for push dispensing is greater than the crack pressure of the check valve for pull dispensing.

5. The cassette assembly of claim 1, comprising a fluid container engaged with one of the multiple inlets.

6. The cassette assembly of claim 1, comprising a first fluid container engaged with a first one of said inlets, and a second fluid container engaged with a second one of said inlets.

7. The cassette assembly of claim 6, wherein the first fluid container contains a buffering medium, and the second fluid container contains an anesthetic composition.

8. The cassette assembly of claim 7, wherein the buffering medium comprises sodium bicarbonate.

9. The cassette assembly of claim 7, wherein the anesthetic composition comprises lidocaine, articaine, or marcaine.

10. The cassette assembly of claim 1, wherein the multiple fluid feed inlets extend vertically upwardly from a top surface of the base manifold member.

11. The cassette assembly of claim 1, further comprising a fluid container adapter coupled to one of the multiple fluid feed inlets for engagement of a fluid container with such inlet, the fluid container adapter being adapted to receive a fluid container including a piercable cap or cover.

12. The cassette assembly of claim 11, wherein the fluid container adapter comprises an air inletting vent enabling air to enter the fluid supply container to facilitate dispensing of fluid therefrom.

13. The cassette assembly of claim 12, wherein the air inletting vent comprises a hydrophobic filter effective to remove airborne contaminants that may adversely affect fluid supplied by the fluid supply container.

14. The cassette assembly of claim 1, wherein the syringe coupling is adapted for engagement with a syringe adapted to be swabable for cleaning and/or sterilization thereof.

15. The cassette assembly of claim 1, adapted as a single-use or disposable assembly.

16. The cassette assembly of claim 15, fabricated predominately of biodegradable plastic and elastomeric material(s) of construction.

17. The cassette assembly of claim 1, comprising a manual gripping element on the base manifold member.

18. The cassette assembly of claim 1, operatively coupled with a syringe fill system that is adapted to dispense fluid to the interior manifold flow passage through a feed fluid inlet of the manifold base member for filling of a syringe when coupled to the syringe coupling mounted on the base manifold member.

19. A kit, comprising the cassette assembly of claim 1, and at least one of:

(i) one or more fluid containers containing fluid, each fluid container being adapted for engagement with one of the fluid feed inlets of the base manifold member; and

/or

(ii) one or more syringes, each adapted for engagement with the syringe coupling mounted on the base manifold member.

20. A method of having a syringe with fluid at a point of use, said method comprising use of the cassette assembly of claim 1, wherein the syringe is coupled with the syringe coupling mounted on the base manifold member of the cassette assembly.