DRUG ELUTION FOR IN VIVO PROTECTION OF BIO-SENSING ANALYTES
First Claim
1. A sensor for measurement of an analyte in a medium within a living animal, the sensor comprising:
- a sensor housing;
an analyte indicator covering at least a portion of the sensor housing; and
one or more therapeutic agents that reduce deterioration of the analyte indicator.
12 Assignments
0 Petitions
Accused Products
Abstract
A sensor (e.g., an optical sensor) that may be implanted within a living animal (e.g., a human) and may be used to measure an analyte (e.g., glucose or oxygen) in a medium (e.g., interstitial fluid, blood, or intraperitoneal fluid) within the animal. The sensor may include a sensor housing, an analyte indicator covering at least a portion of the sensor housing, and one or more therapeutic agents. The one or more therapeutic agents may reduce deterioration of the analyte indicator. The one or more therapeutic agents may be incorporated within the analyte indicator, a membrane covering at least a portion of the analyte indicator, and/or one or more drug eluting polymer matrices, which may be external to or within the sensor housing.
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Citations
47 Claims
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1. A sensor for measurement of an analyte in a medium within a living animal, the sensor comprising:
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a sensor housing; an analyte indicator covering at least a portion of the sensor housing; and one or more therapeutic agents that reduce deterioration of the analyte indicator. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41)
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42. A sensor for measurement of an analyte in a medium within a living animal, the sensor comprising:
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a sensor housing; an analyte indicator covering at least a portion of the sensor housing; a layer of a catalyst that facilitates the conversion of hydrogen peroxide into water and oxygen on at least a portion of the analyte indicator; and at least one drug eluting polymer matrix dispersed within the drug eluting polymer matrix, wherein the one or more therapeutic agents reduce deterioration of the analyte indicator. - View Dependent Claims (43, 44, 45, 46, 47)
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Specification