Selecting and Delivering Treatment Agents based on a Microbe Profile

• US 20150057574A1
• Filed: 04/17/2014
• Published: 02/26/2015
• Est. Priority Date: 08/23/2013
• Status: Abandoned Application

• Current Assignee: Elwha LLC (Intellectual Ventures LLC)
• Original Assignee: Elwha LLC (Intellectual Ventures LLC)
• Inventors: Baym, Michael H., Hyde, Roderick A., Kare, Jordin T., Leuthardt, Eric C., McKnight, Gary L., Pan, Tony S., Sweeney, Elizabeth A., Tegreene, Clarence T., Wood, Lowell L. Jr.
• Application Number:
  US14/255,653
• Publication Number:
  US 20150057574A1
• Time in Patent Office: Days
• US Class Current: 600/570
• CPC Class Codes: A61B 10/00 Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis vaccination prophylaxis, vaccination therapy A61B17/20; Sex determination; Ovulation-period determination menstruation tables G06C3/00; Throat striking implements
• CPC Class Codes: G16H 10/40 for data related to laboratory analysis, e.g. patient specimen analysis
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 20/13 delivered from dispensers
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: Y02A 90/10 Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

Kits, devices, methods, and systems for assessing microbiota of a body surface and selecting treatment agents to apply to the body surface to modulate one or more types of microbes are described which include a kit including a plurality of treatment agents, a microbe sampling unit including a microbe-capture region, and an analyzer including a user interface, at least one sensor component, and a computing component with a processor and circuitry.

Claims

1. A kit, comprising:

a plurality of treatment agents;

a microbe sampling unit having at least one surface with a microbe-capture region, the microbe-capture region configured to capture one or more types of microbes from a body surface of a user; and

an analyzer including

at least one sensor component including circuitry configured to detect one or more signals emitted or reflected from the microbe-capture region of the microbe sampling unit and to transform the detected one or more signals into a sensor output;

a user interface; and

a computing component including a processor and operably coupled to the at least one sensor component and the user interface, the computing component including circuitry configured to

receive the sensor output from the at least one sensor component, the sensor output including information associated with at least one property of the detected one or more signals emitted or reflected from the microbe-capture region of the microbe sampling unit;

compare the at least one property of the detected one or more signals emitted or reflected from the microbe-capture region of the microbe sampling unit with a reference dataset of signal properties;

generate a microbe profile of the user based on the comparison with the reference dataset of signal properties;

compare the microbe profile of the user with at least one reference microbe profile; and

recommend to the user at least one of the plurality of treatment agents based on the comparison with the at least one reference microbe profile.

2. The kit of claim 1, wherein the plurality of treatment agents comprises at least one first treatment agent in at least one first container and at least one second treatment agent in at least one second container.

3. The kit of claim 2, wherein the plurality of treatment agents comprises at least one third treatment agent in at least one third container.

4. The kit of claim 1, wherein the plurality of treatment agents comprises one or more probiotic agents.

5. The kit of claim 4, wherein the one or more probiotic agents comprise at least one type of bacteria from Firmicutes, Actinobacteria, Bacteriodetes, Proteobacteria, or Cyanobacteria.

6. The kit of claim 4, wherein the one or more probiotic agents comprise at least one type of bacteria from Corynebacteria, Propionibacteria, Micrococci, or Staphylococci.

7. The kit of claim 4, wherein the one or more probiotic agents comprise at least one of a non-pathogenic strain of a pathogenic bacterium.

8. The kit of claim 4, wherein the one or more probiotic agents comprise Staphylococcus epidermidis.

9. The kit of claim 1, wherein the plurality of treatment agents comprise one or more prebiotic agents.

10. The kit of claim 9, wherein the one or more prebiotic agents comprise at least one of oligosaccharides, inulin, or lactulose.

11. The kit of claim 1, wherein the plurality of treatment agents comprise one or more antimicrobial agents.

12. The kit of claim 11, wherein the one or more antimicrobial agents comprise at least one of an antibacterial agent, an antifungal agent, or an antiviral agent.

13. The kit of claim 1, wherein the plurality of treatment agents comprise one or more therapeutic agents.

14. The kit of claim 13, wherein the one or more therapeutic agents comprise at least one of an anti-inflammatory agent, a chemotherapeutic agent, an antiseptic agent, an anesthetic agent, or an anti-acne agent.

15. The kit of claim 1, wherein the plurality of treatment agents comprise at least one of a moisturizer, an astringent, an anti-aging treatment agent, a retinoid agent, or a cosmetic agent.

16. The kit of claim 1, wherein the microbe-capture region of the microbe sampling unit is configured to capture one or more types of microbes from a skin surface of the user.

17. The kit of claim 1, wherein the microbe-capture region of the microbe sampling unit is configured to capture one or more types of microbes from a gastrointestinal surface of the user.

18. The kit of claim 1, wherein the microbe-capture region of the microbe sampling unit is configured to capture one or more types of microbes from a mucosal surface, a vaginal surface, a nasal surface, or a mouth surface of the user.

19. The kit of claim 1, wherein the microbe sampling unit comprises a mask.

20. The kit of claim 19, wherein the mask comprises a pre-formed mask.

21. The kit of claim 19, wherein the mask comprises a peelable mask.

22. The kit of claim 1, wherein the microbe sampling unit comprises a mouthpiece.

23. The kit of claim 1, wherein the microbe sampling unit comprises a strip.

24. The kit of claim 1, wherein the microbe sampling unit includes at least one optical sensor.

25. The kit of claim 1, wherein the microbe sampling unit substantially conforms to a topography of the body surface of the user.

26. The kit of claim 1, wherein the microbe sampling unit comprises a swab.

27. The kit of claim 1, wherein the microbe sampling unit comprises a brush.

28. The kit of claim 1, wherein the microbe sampling unit comprises a razor.

29. The kit of claim 1, wherein the microbe sampling unit is personalized for the user.

30. The kit of claim 1, wherein the microbe sampling unit and the analyzer are incorporated into a hand-held microbe profiling device.

31. The kit of claim 30, wherein the hand-held microbe profiling device includes a brush head.

32. The kit of claim 30, wherein the hand-held microbe profiling device includes a razor head.

33. The kit of claim 30, wherein the hand-held microbe profiling device includes a rotatable microbe sampling unit including the microbe-capture region.

34. The kit of claim 30, wherein the hand-held microbe profiling device includes a vacuum.

35. The kit of claim 1, wherein the microbe-capture region of the microbe sampling unit comprises a charged surface.

36. The kit of claim 1, wherein the microbe-capture region of the microbe sampling unit comprises at least one of an adhesive, an absorbent, or an adsorbent.

37. The kit of claim 1, wherein the microbe-capture region of the microbe sampling unit comprises a biomolecule-binding polymer.

38. The kit of claim 1, wherein the microbe-capture region of the microbe sampling unit comprises a gel.

39. The kit of claim 1, wherein the microbe-capture region of the microbe sampling unit comprises a plurality of specific microbe-binding elements.

40. The kit of claim 39, wherein at least one of the plurality of specific microbe-binding elements comprises a specific microbe-binding antibody.

41. The kit of claim 39, wherein at least one of the plurality of specific microbe-binding elements comprises a specific microbe-binding oligonucleotide.

42. The kit of claim 39, wherein at least one of the plurality of specific microbe-binding elements comprises a protein, a peptide, DNA, RNA, a lectin, a carbohydrate, an anti-16S rRNA ligand, an aptamer, a synthetic ligand, or a mimetic binding element.

43. The kit of claim 39, wherein the microbe-capture region comprises a plurality of specific microbe-binding elements of at least one first type and a plurality of specific microbe-binding elements of at least one second type.

44. The kit of claim 1, wherein the microbe-capture region of the microbe sampling unit comprises a plurality of signal-generating complexes.

45. The kit of claim 44, wherein at least one of the plurality of signal-generating complexes comprises an optical signal-generating complex, a fluorescing signal-generating complex, electromagnetic signal-generating complex, a radio signal-generating complex, an electrical current signal-generating complex, an acoustic signal-generating complex, or a magnetic signal-generating complex.

46. The kit of claim 44, wherein the microbe-capture region comprises a plurality of signal-generating complexes of at least one first type able to emit at least one first signal type in response to at least one first type of microbe and a plurality of signal-generating complexes of at least one second type able to emit at least one second signal type in response to at least one second type of microbe.

47. The kit of claim 44, wherein each of the plurality of signal-generating complexes comprises at least one signal-generating element operably coupled to at least one specific microbe-binding element, the at least one signal-generating element configured to emit one or more signals in response to contact with at least one type of microbe by the operably coupled at least one specific microbe-binding element.

48. The kit of claim 1, wherein the analyzer includes a receptacle sized to fit at least a portion of the microbe sampling unit.

49. The kit of claim 1, wherein the at least one sensor component of the analyzer includes at least one optical sensor.

50. The kit of claim 1, wherein the at least one sensor component of the analyzer includes at least one fluorescence sensor.

51. The kit of claim 1, wherein the at least one sensor component of the analyzer includes at least one of an electromagnetic sensor component, an electrical current sensor component, a piezoelectric sensor component, a magnetic sensor component, an acoustic sensor component, a radiofrequency sensor component, or a radioactivity sensor component.

52. The kit of claim 1, wherein the at least one sensor component of the analyzer includes circuitry configured to detect one or more signals emitted or reflected from at least one of the one or more types of microbes captured on the microbe-capture region of the microbe sampling unit.

53. The kit of claim 1, wherein the at least one sensor component of the analyzer includes circuitry configured to detect one or more signals emitted or reflected from at least one of a plurality of signal-generating elements associated with the one or more types of microbes captured on the microbe-capture region of the microbe sampling unit.

54. The kit of claim 1, wherein the at least one sensor component of the analyzer includes circuitry configured to detect one or more signals emitted from at least one of a plurality of signal-generating complexes associated with the microbe sampling unit in response to contact with at least one of the one or more types of microbes.

55. The kit of claim 1, wherein the user interface of the analyzer includes at least one of a display, touchscreen, keyboard, microphone, speaker, mouse, joystick, buttons, switches, or printer.

56. The kit of claim 1, wherein the analyzer further includes one or more reservoirs.

57. The kit of claim 56, wherein at least one of the one or more reservoirs includes a plurality of at least one type of signal-generating element.

58. The kit of claim 56, wherein at least one of the one or more reservoirs includes at least one of a buffer, a detergent solution, a reagent solution, or a wash solution.

59. The kit of claim 1, wherein the at least one property of the detected one or more signals emitted or reflected from the microbe-capture region of the microbe sampling unit comprises at least one of an optical property, a fluorescent property, a magnetic property, an electrical property, an electromagnetic property, an acoustic property, or a radiofrequency property.

60. The kit of claim 1, wherein the reference dataset of signal properties includes properties of one or more signals emitted or reflected from a given type of microbe.

61. The kit of claim 1, wherein the reference dataset of signal properties includes properties of one or more signals emitted from a given type of signal-generating element.

62. The kit of claim 1, wherein the reference dataset of signal properties includes properties of one or more signals emitted from a given type of signal-generating complex.

63. The kit of claim 1, wherein the reference dataset of signal properties is included in a memory component of the computing component of the analyzer.

64. The kit of claim 1, wherein the reference dataset of signal properties is accessed from a remote computing device through a communication link.

65. The kit of claim 1, wherein the at least one reference microbe profile includes at least one historical microbe profile of the user.

66. The kit of claim 1, wherein the at least one reference microbe profile includes at least one microbe profile from one or more other individuals.

67. The kit of claim 1, wherein the at least one reference microbe profile includes at least one theoretical microbe profile.

68. The kit of claim 1, wherein the at least one reference microbe profile is included in a memory component of the computing component of the analyzer.

69. The kit of claim 1, wherein the at least one reference microbe profile is accessed from a remote computing device through a communication link.

70. The kit of claim 1, wherein the analyzer further includes a transmission unit including an antenna.

71. The kit of claim 1, wherein the computing component of the analyzer includes circuitry configured to recommend to the user at least one of the plurality of treatment agents based on an identity of one or more types of microbes in the microbe profile.

72. The kit of claim 1, wherein the computing component of the analyzer includes circuitry configured to recommend to the user at least one of the plurality of treatment agents based on an identity of one or more types of microbes in the microbe profile and one or more other factors.

73. The kit of claim 72, wherein the one or more other factors include one or more of age, gender, ethnicity, skin characteristic, geographical location, medical history, co-morbidities, or user preference.

74. The kit of claim 72, wherein the one or more other factors include at least one user preference.

75. The kit of claim 1, wherein the computing component of the analyzer includes circuitry to receive user information from the user through the user interface.

76. The kit of claim 75, wherein the user information includes at least one of age, gender, ethnicity, skin characteristic, geographical location, medical history, co-morbidities, or user preference.

77. The kit of claim 1, wherein the computing component of the analyzer includes circuitry configured to report at least one of the microbe profile, the recommended at least one of the plurality of treatment agents, user information, or other information to one or more of a medical record, a healthcare provider, a pharmacy, a cosmetologist, a merchant, a supplier, or a manufacturer.

78. The kit of claim 1, wherein the computing component of the analyzer includes circuitry configured to report at least one of the microbe profile, the recommended at least one of the plurality of treatment agents, user information, or other information to at least one of a website, a social media site, or a personal computing device.

79. The kit of claim 1, wherein the computing component of the analyzer includes circuitry configured to automatically call out to at least one of a healthcare provider, a pharmacy, a cosmetologist, a merchant, a supplier, or a manufacturer to request resupply of at least one of the plurality of treatment agents.

80. The kit of claim 1, wherein the computing component of the analyzer includes circuitry configured to

store the microbe profile in a memory component of the computing component;

chart changes in the microbe profile over time as the analyzer generates one or more additional microbe profiles of the user; and

report the charted changes in the microbe profile to the user.

81. The kit of claim 1, further including a set of user instructions for using the kit.

82. The kit of claim 81, wherein the set of user instructions is on non-transitory machine readable media.

83. The kit of claim 81, wherein the set of instructions includes at least one of one or more instructions for sampling the body surface of the user with the microbe sampling unit, one or more instructions for using the analyzer, one or more instructions for interpreting the microbe profile, one or more instructions for applying the recommended at least one of the plurality of treatment agents to the body surface, or one or more instructions for accessing a website.

84. A kiosk, comprising:

a plurality of treatment agents;

one or more dispensers to dispense at least one of the plurality of treatment agents;

at least one microbe sampling unit, the at least one microbe sampling unit including at least one surface with a microbe-capture region, the microbe-capture region configured to capture one or more types of microbes from a body surface of a user;

a user interface;

at least one sensor component including circuitry configured to detect one or more signals emitted or reflected from the microbe-capture region of the at least one microbe sampling unit and to transform the detected one or more signals into a signal output; and

a computing component including a processor and operably coupled to the one or more dispensers, the at least one sensor component, and the user interface, the computing component including circuitry configured to

receive the sensor output from the at least one sensor component, the sensor output including information associated with at least one property of the detected one or more signals emitted or reflected from the microbe-capture region of the at least one microbe sampling unit;

compare the at least one property of the detected one or more signals emitted or reflected from the microbe-capture region of the at least one microbe sampling unit with a reference dataset of signal properties;

generate a microbe profile of the user based on the comparison with the reference dataset of signal properties;

compare the microbe profile of the user with at least one reference microbe profile;

recommend at least one of the plurality of treatment agents to the user based on the comparison with the at least one reference microbe profile; and

send a signal to at least one of the one or more dispensers to dispense the recommended at least one of the plurality of treatment agents from the kiosk to the user.

85. The kiosk of claim 84, further including a microbe sampling unit dispensing component operably coupled to the computing component, the microbe sampling unit dispensing component to dispense the at least one microbe sampling unit to the user.

86. The kiosk of claim 84, further including at least one receiving component operably coupled to the computing component, the receiving component to receive the at least one microbe sampling unit from the user.

87. The kiosk of claim 86, wherein the at least one receiving component includes a feeding mechanism.

88. The kiosk of claim 84, wherein the plurality of treatment agents comprise at least one first treatment agent in at least one first container and at least one second treatment agent in at least one second container.

89. The kiosk of claim 88, wherein the plurality of treatment agents comprises at least one third treatment agent in at least one third container.

90. The kiosk of claim 84, wherein the plurality of treatment agents comprise at least one first treatment agent dispensable by at least one first dispenser and at least one second treatment agent dispensable by at least one of the at least one first dispenser or at least one second dispenser.

91. The kiosk of claim 84, wherein the plurality of treatment agents comprises one or more probiotic agents.

92. The kiosk of claim 91, wherein the one or more probiotic agents comprise at least one type of bacteria from Firmicutes, Actinobacteria, Bacteriodetes, Proteobacteria, or Cyanobacteria.

93. The kiosk of claim 91, wherein the one or more probiotic agents comprise at least one type of bacteria from Corynebacteria, Propionibacteria, Micrococci, or Staphylococci.

94. The kiosk of claim 91, wherein the one or more probiotic agents comprise at least one of a non-pathogenic strain of a pathogenic bacterium.

95. The kiosk of claim 91, wherein the one or more probiotics comprise Staphylococcus epidermidis.

96. The kiosk of claim 84, wherein the plurality of treatment agents comprise one or more prebiotic agents.

97. The kiosk of claim 96, wherein the one or more prebiotic agents comprise at least one of oligosaccharides, inulin, or lactulose.

98. The kiosk of claim 84, wherein the plurality of treatment agents comprise one or more antimicrobial agents.

99. The kiosk of claim 98, wherein the one or more antimicrobial agents comprise at least one of an antibacterial agent, an antifungal agent, or an antiviral agent.

100. The kiosk of claim 84, wherein the plurality of treatment agents comprise one or more therapeutic agents.

101. The kiosk of claim 100, wherein the one or more therapeutic agents comprise at least one of an anti-inflammatory agent, a chemotherapeutic agent, an antiseptic agent, an anesthetic agent, or an anti-acne agent.

102. The kiosk of claim 84, wherein the plurality of treatment agents comprise at least one of a moisturizer, an astringent, an anti-aging treatment agent, a retinoid agent, or a cosmetic agent.

103. The kiosk of claim 84, wherein the microbe-capture region of the at least one microbe sampling unit is configured to capture one or more types of microbes from a skin surface of the user.

104. The kiosk of claim 84, wherein the microbe-capture region of the at least one microbe sampling unit is configured to capture one or more types of microbes from a gastrointestinal surface of the user.

105. The kiosk of claim 84, wherein the microbe-capture region of the at least one microbe sampling unit is configured to capture one or more types of microbes from a mucosal surface, a vaginal surface, a nasal surface, or a mouth surface of the user.

106. The kiosk of claim 84, wherein the at least one microbe sampling unit comprises a mask.

107. The kiosk of claim 106, wherein the mask comprises a preformed mask.

108. The kiosk of claim 106, wherein the mask comprises a peelable mask.

109. The kiosk of claim 84, wherein the at least one microbe sampling unit comprises a mouthpiece.

110. The kiosk of claim 84, wherein the at least one microbe sampling unit comprises a strip.

111. The kiosk of claim 84, wherein the at least one microbe sampling unit substantially conforms to a topography of the body surface of the user.

112. The kiosk of claim 84, wherein the at least one microbe sampling unit comprises an optical sensor.

113. The kiosk of claim 84, wherein the at least one microbe sampling unit comprises a swab.

114. The kiosk of claim 84, wherein the at least one microbe sampling unit comprises a brush.

115. The kiosk of claim 84, wherein the at least one microbe sampling unit comprises a razor.

116. The kiosk of claim 84, wherein the at least one microbe sampling unit includes a rotatable microbe-capture region.

117. The kiosk of claim 84, wherein the at least one microbe sampling unit is personalized for the user.

118. The kiosk of claim 84, wherein the microbe-capture region of the at least one microbe sampling unit comprises a charged surface.

119. The kiosk of claim 84, wherein the microbe-capture region of the at least one microbe sampling unit comprises at least one of an adhesive, an absorbent, or an adsorbent.

120. The kiosk of claim 84, wherein the microbe-capture region of the at least one microbe sampling unit comprises a biomolecule-binding polymer.

121. The kiosk of claim 84, wherein the microbe-capture region of the at least one microbe sampling unit comprises a gel.

122. The kiosk of claim 84, wherein the microbe-capture region of the microbe sampling unit comprises a plurality of specific microbe-binding elements.

123. The kiosk of claim 122, wherein at least one of the plurality of specific microbe-binding elements comprises a specific microbe-binding antibody.

124. The kiosk of claim 122, wherein at least one of the plurality of specific microbe-binding elements comprises a specific microbe-binding oligonucleotide.

125. The kiosk of claim 122, wherein at least one of the plurality of specific microbe-binding elements comprises a protein, a peptide, a lectin, a carbohydrate, RNA, DNA, an anti-16S rRNA ligand, an aptamer, a synthetic ligand, or a mimetic binding element.

126. The kiosk of claim 122, wherein the microbe-capture region comprises a plurality of specific microbe-binding elements of at least one first type and a plurality of specific microbe-binding elements of at least one second type.

127. The kiosk of claim 84, wherein the microbe capture region of the at least one microbe sampling unit comprises a plurality of signal-generating complexes.

128. The kiosk of claim 127, wherein at least one of the plurality of signal-generating complexes comprises an optical signal-generating complex, a fluorescing signal-generating complex, electromagnetic signal-generating complex, a radio signal-generating complex, an electrical current signal-generating complex, an acoustic signal-generating complex, or a magnetic signal-generating complex.

129. The kiosk of claim 127, wherein each of the plurality of signal-generating complexes comprises at least one signal-generating element operably coupled to at least one specific microbe-binding element, the at least one signal-generating element configured to emit one or more signals in response to contact with at least one type of microbe by the operably coupled at least one specific microbe-binding element.

130. The kiosk of claim 127, wherein the microbe-capture region comprises a plurality of signal-generating complexes of at least one first type able to emit at least one first signal type in response to at least one first type of microbe and a plurality of signal-generating complexes of at least one second type able to emit at least one second signal type in response to at least one second type of microbe.

131. The kiosk of claim 84, wherein the at least one sensor component includes at least one optical sensor.

132. The kiosk of claim 84, wherein the at least one sensor component includes at least one fluorescence sensor.

133. The kiosk of claim 84, wherein the at least one sensor component includes at least one of an electromagnetic sensor component, an electrical current sensor component, a piezoelectric sensor component, a magnetic sensor component, an acoustic sensor component, a radiofrequency sensor component, or a radioactivity sensor component.

134. The kiosk of claim 84, wherein the at least one sensor component includes circuitry configured to detect one or more signals emitted or reflected from at least one of the one or more types of microbes captured on the microbe-capture region of the at least one microbe sampling unit.

135. The kiosk of claim 84, wherein the at least one sensor component includes circuitry configured to detect one or more signals emitted or reflected from at least one of a plurality of signal-generating elements associated with the one or more types of microbes captured on the microbe-capture region of the at least one microbe sampling unit.

136. The kiosk of claim 84, wherein the at least one sensor component includes circuitry configured to detect one or more signals emitted from at least one of a plurality of signal-generating complexes associated with the at least one microbe sampling unit in response to contact with at least one of the one or more types of microbes.

137. The kiosk of claim 84, wherein the user interface includes at least one of a display, touchscreen, keyboard, microphone, speaker, mouse, joystick, buttons, switches, or printer.

138. The kiosk of claim 84, wherein the kiosk further includes one or more reservoirs.

139. The kiosk of claim 138, wherein at least one of the one or more reservoirs includes a plurality of at least one type of signal-generating element.

140. The kiosk of claim 138, wherein at least one of the one or more reservoirs includes at least one of a buffer, a detergent solution, a reagent solution, or a wash solution.

141. The kiosk of claim 84, wherein the at least one property of the detected one or more signals emitted or reflected from the microbe-capture region of the microbe sampling unit comprises at least one of an optical property, a fluorescent property, a magnetic property, an electrical property, an electromagnetic property, or a radiofrequency property.

142. The kiosk of claim 84, wherein the reference dataset of signal properties includes properties of one or more signals emitted or reflected from a given type of microbe.

143. The kiosk of claim 84, wherein the reference dataset of signal properties includes properties of one or more signals emitted from a given type of signal-generating element.

144. The kiosk of claim 84, wherein the reference dataset of signal properties includes properties of one or more signals emitted from a given type of signal-generating complex.

145. The kiosk of claim 84, wherein the reference dataset of signal properties is included in a memory component of the computing component.

146. The kiosk of claim 84, wherein the reference dataset of signal properties is accessed from a remote computing device through a communication link.

147. The kiosk of claim 84, wherein the at least one reference microbe profile comprises at least one historical microbe profile of the user.

148. The kiosk of claim 84, wherein the at least one reference microbe profile comprises at least one microbe profile from one or more other individuals.

149. The kiosk of claim 84, wherein the at least one reference microbe profile comprises at least one theoretical microbe profile.

150. The kiosk of claim 84, wherein the at least one reference microbe profile is included in a memory component of the computing component.

151. The kiosk of claim 84, wherein the at least one reference microbe profile is accessed from a remote computing device through a communication link.

152. The kiosk of claim 84, further including a transmission unit including an antenna.

153. The kiosk of claim 84, wherein the computing component includes circuitry configured to recommend to the user at least one of the plurality of treatment agents based on an identity of one or more types of microbes in the microbe profile of the user.

154. The kiosk of claim 84, wherein the computing component includes circuitry configured to recommend to the user at least one of the plurality of treatment agents based on an identity of one or more types of microbes included in the microbe profile of the user and one or more other factors.

155. The kiosk of claim 154, wherein the one or more other factors include one or more of age, gender, ethnicity, skin characteristic, geographical location, medical history, or co-morbidities.

156. The kiosk of claim 154, wherein the one or more other factors include at least one user preference.

157. The kiosk of claim 84, wherein the computing component includes circuitry configured to receive user information from the user through the user interface.

158. The kiosk of claim 157, wherein the user information includes at least one of age, gender, ethnicity, skin characteristics, geographical location, medical history, co-morbidities, or user preferences.

159. The kiosk of claim 84, wherein the computing component includes circuitry configured to report at least one of the microbe profile, the recommended at least one of the plurality of treatment agents, user information, or other information to one or more of a medical record, a healthcare provider, a pharmacy, a cosmetologist, a merchant, a supplier, or a manufacturer.

160. The kiosk of claim 84, wherein the computing component includes circuitry configured to report at least one of the microbe profile, the recommended at least one of the plurality of treatment agents, user information, or other information to at least one of a website, a social media site, or a personal computing device.

161. The kiosk of claim 84, wherein the computing component includes circuitry configured to automatically call out to at least one of a healthcare provider, a pharmacy, a cosmetologist, a merchant, a supplier, or a manufacturer to request resupply of at least one of the plurality of treatment agents.

162. The kiosk of claim 84, wherein the computing component includes circuitry configured to receive one or more user identifiers.

163. The kiosk of claim 84, wherein the computing component includes circuitry configured to attach one or more user identifiers to the microbe profile of the user.

164. The kiosk of claim 84, wherein the computing component includes circuitry configured to

store the microbe profile of the user in a memory component of the computing component;

chart changes in the microbe profile over time as the computing component generates one or more additional microbe profiles of the user; and

report the charted changes in the microbe profile to the user.

165. The kiosk of claim 84, further including a set of user instructions for using the kiosk or a component of the kiosk.

166. The kiosk of claim 165, wherein the set of user instructions includes at least one of one or more instructions for using the kiosk, one or more instructions for sampling the body surface of the user with the at least one microbe sampling unit, one or more instructions for inserting the at least one microbe sampling unit into at least one receiving component of the kiosk, one or more instructions for interpreting the microbe profile, one or more instructions for applying the recommended at least one of the plurality of treatment agents to the body surface, or one or more instructions for accessing a website.

167. A method, comprising:

receiving information associated with a microbe profile of an individual from a remote source, the microbe profile including a distribution of one or more types of microbes on a body surface of the individual;

selecting one or more treatment agents from a list of available treatment agents to apply to the body surface to modulate the one or more types of microbes on the body surface of the individual; and

arranging for delivery of the selected one or more treatment agents.

168. The method of claim 167, further comprising:

comparing the information associated with the microbe profile of the individual with at least one reference microbe profile; and

selecting the one or more treatment agents from the list of available treatment agents based on the comparison of the information associated with the microbe profile of the individual with the at least one reference microbe profile.

169. The method of claim 167, wherein comparing the information associated with the microbe profile of the individual with the at least one reference microbe profile comprises comparing the information associated with the microbe profile of the individual with at least one historical microbe profile of the individual.

170. The method of claim 167, wherein comparing the information associated with the microbe profile of the individual with the at least one reference microbe profile comprises comparing the information associated with the microbe profile of the individual with at least one microbe profile of one or more other individuals.

171. The method of claim 167, wherein comparing the information associated with the microbe profile of the individual with the at least one reference microbe profile comprises comparing the information associated with the microbe profile of the individual with at least one theoretical microbe profile.

172. The method of claim 167, wherein receiving the information associated with the microbe profile of the individual from the remote source comprises automatically receiving the information associated with the microbe profile of the individual from the remote source.

173. The method of claim 167, wherein receiving the information associated with the microbe profile of the individual comprises receiving the information associated with the microbe profile of the individual with a computing device.

174. The method of claim 167, wherein receiving the information associated with the microbe profile of the individual from the remote source comprises receiving the information associated with the microbe profile of the individual from a remote computing device.

175. The method of claim 167, wherein receiving the information associated with the microbe profile of the individual from the remote source comprises receiving the information associated with the microbe profile of the individual from an analyzer of a microbe profiling kit.

176. The method of claim 167, wherein receiving the information associated with the microbe profile of the individual from the remote source comprises receiving the information associated with the microbe profile of the individual from a kiosk.

177. The method of claim 167, wherein receiving the information associated with the microbe profile of the individual from the remote source comprises receiving the information associated with the microbe profile of the individual from a microbe profiling device.

178. The method of claim 167, wherein selecting the one or more treatment agents from the list of available treatment agents comprises selecting at least one of a probiotic agent, a prebiotic agent, an antimicrobial agent, a therapeutic agent, an anti-aging agent, an antiseptic agent, an anesthetic agent, an anti-acne agent, a cosmetic agent, a moisturizing agent, an astringent agent, a sunscreen agent, or a retinoid agent.

179. The method of claim 167, wherein selecting the one or more treatment agents from a list of available treatment agents comprises selecting the one or more treatment agents from a list of available treatment agents stored in at least one dataset.

180. The method of claim 167, wherein selecting the one or more treatment agents from a list of available treatment agents comprises selecting the one or more treatment agents from a list of available treatment agents stored in at least one look-up table.

181. The method of claim 167, wherein selecting the one or more treatment agents from the list of available treatment agents to treat the one or more types of microbes on the body surface of the individual comprises selecting the one or more treatment agents from the list of available treatment agents to modulate the one or more types of microbes on a skin surface of the individual.

182. The method of claim 167, wherein selecting the one or more treatment agents from the list of available treatment agents to treat the one or more types of microbes on the body surface of the individual comprises selecting the one or more treatment agents from the list of available treatment agents to modulate the one or more types of microbes on a gastrointestinal surface of the individual.

183. The method of claim 167, wherein selecting the one or more treatment agents from the list of available treatment agents to treat the one or more types of microbes on the body surface of the individual comprises selecting the one or more treatment agents from the list of available treatment agents to modulate the one or more types of microbes on a mucosal surface, a vaginal surface, a nasal surface, or an oral surface of the individual.

184. The method of claim 167, further including selecting the one or more treatment agents from the list of available treatment agents based on the microbe profile of the individual and one or more other factors.

185. The method of claim 184, wherein selecting the one or more treatment agents from the list of available treatment agents based on the microbe profile of the individual and the one or more other factors comprises selecting the one or more treatment agents from the list of available treatment agents based on the microbe profile of the individual and one or more of age, gender, ethnicity, skin characteristics, geographical location, medical history, co-morbidities, or user preferences.

186. The method of claim 184, wherein selecting the one or more treatment agents from the list of available treatment agents comprises automatically selecting the one or more treatment agents from the list of available treatment agents.

187. The method of claim 167, further including receiving user information from the individual.

188. The method of claim 187, wherein receiving user information from the individual comprises receiving age, gender, ethnicity, skin characteristic, geographical location, medical history, co-morbidities, or user preferences from the individual.

189. The method of claim 167, wherein arranging for the delivery of the selected one or more treatment agents comprises automatically arranging for the delivery of the selected one or more treatment agents.

190. The method of claim 167, wherein arranging for the delivery of the selected one or more treatment agents comprises arranging for the delivery of the selected one or more treatment agents to a street address.

191. The method of claim 167, wherein arranging for the delivery of the selected one or more treatment agents comprises arranging for the delivery of the selected one or more treatment agents to a postal address.

192. The method of claim 167, wherein arranging for the delivery of the selected one or more treatment agents comprises arranging for the delivery of the selected one or more treatment agents to a residence, a post office, a delivery service office, a store, a pharmacy, a medical office, or a cosmetic counter.

193. The method of claim 167, further comprising:

notifying the individual that delivery of the selected one or more treatment agents has been arranged.

194. The method of claim 193, wherein notifying the individual comprises notifying the individual by at least one of an electronic communication, a telephonic communication, or a written communication.

195. A system, comprising:

circuitry for receiving information associated with a microbe profile of an individual from a remote source, the microbe profile including a distribution of one or more types of microbes on a body surface of the individual;

circuitry for selecting one or more treatment agents from a list of available treatment agents to apply to the body surface to modulate the one or more types of microbes on the body surface of the individual; and

circuitry for arranging for delivery of the selected one or more treatment agents.

196. The system of claim 195, further comprising:

a computing device.

197. The system of claim 195, further comprising:

circuitry for comparing the information associated with the microbe profile of the individual with at least one reference microbe profile; and

circuitry for selecting the one or more treatment agents from the list of available treatment agents based on the comparison of the information associated with the microbe profile of the individual with the at least one reference microbe profile.

198. The system of claim 197, wherein the circuitry for comparing the information associated with the microbe profile of the individual with the at least one reference microbe profile comprises circuitry for comparing the information associated with the microbe profile of the individual with at least one historical microbe profile of the individual.

199. The system of claim 197, wherein the circuitry for comparing the information associated with the microbe profile of the individual with the at least one reference microbe profile comprises circuitry for comparing the information associated with the microbe profile of the individual with at least one microbe profile of one or more other individuals.

200. The system of claim 197, wherein the circuitry for comparing the information associated with the microbe profile of the individual with the at least one reference microbe profile comprises circuitry for comparing the information associated with the microbe profile of the individual with at least one theoretical microbe profile.

201. The system of claim 195, wherein the circuitry for receiving the information associated with the microbe profile of the individual from the remote source comprises circuitry for automatically receiving the information associated with the microbe profile of the individual from the remote source.

202. The system of claim 195, wherein the circuitry for receiving the information associated with the microbe profile of the individual comprises circuitry for receiving the information associated with the microbe profile of the individual with a computing device.

203. The system of claim 195, wherein the circuitry for receiving the information associated with the microbe profile of the individual from the remote source comprises circuitry for receiving the information associated with the microbe profile of the individual from a remote computing device.

204. The system of claim 195, wherein the circuitry for receiving the information associated with the microbe profile of the individual from the remote source comprises circuitry for receiving the information associated with the microbe profile of the individual from an analyzer of a microbe profiling kit.

205. The system of claim 195, wherein the circuitry for receiving the information associated with the microbe profile of the individual from the remote source comprises circuitry for receiving the information associated with the microbe profile of the individual from a kiosk.

206. The system of claim 195, wherein the circuitry for receiving the information associated with the microbe profile of the individual from the remote source comprises circuitry for receiving the information associated with the microbe profile of the individual from a microbe profiling device.

207. The system of claim 195, wherein the circuitry for selecting the one or more treatment agents from the list of available treatment agents comprises circuitry for selecting at least one of a probiotic, a prebiotic, an antimicrobial, a therapeutic agent, an anti-aging agent, an antiseptic, an anesthetic agent, an anti-acne agent, a cosmetic agent, a moisturizing agent, an astringent agent, a sunscreen agent, or a retinoid agent.

208. The system of claim 195, wherein the circuitry for selecting the one or more treatment agents from a list of available treatment agents comprises circuitry for selecting one or more treatment agents from a list of available treatment agents stored in at least one dataset.

209. The system of claim 195, wherein the circuitry for selecting the one or more treatment agents from a list of available treatment agents comprises circuitry for selecting one or more treatment agents from a list of available treatment agents stored in at least one look-up table.

210. The system of claim 195, wherein the circuitry for selecting the one or more treatment agents from the list of available treatment agents to apply to the body surface to modulate the one or more types of microbes on the body surface of the individual comprises circuitry for selecting the one or more treatment agents from the list of available treatment agents to modulate the one or more types of microbes on a skin surface of the individual.

211. The system of claim 195, wherein the circuitry for selecting the one or more treatment agents from the list of available treatment agents to apply to the body surface to modulate the one or more types of microbes on the body surface of the individual comprises circuitry for selecting the one or more treatment agents from the list of available treatment agents to modulate the one or more types of microbes on a gastrointestinal surface of the individual.

212. The system of claim 195, wherein the circuitry for selecting the one or more treatment agents from the list of available treatment agents to apply to the body surface to modulate the one or more types of microbes on the body surface of the individual comprises circuitry for selecting the one or more treatment agents from the list of available treatment agents to modulate the one or more types of microbes on a mucosal surface, a vaginal surface, a nasal surface, or an oral surface of the individual.

213. The system of claim 195, further including circuitry for selecting the one or more treatment agents from the list of available treatment agents based on the microbe profile of the individual and one or more other factors.

214. The method of claim 213, wherein the circuitry for selecting the one or more treatment agents from the list of available treatment agents based on the microbe profile of the individual and the one or more other factors comprises circuitry for selecting the one or more treatment agents from the list of available treatment agents based on the microbe profile of the individual and one or more of age, gender, ethnicity, skin characteristics, geographical location, medical history, co-morbidities, or user preferences.

215. The system of claim 195, wherein the circuitry for selecting the one or more treatment agents from the list of available treatment agents comprises automatically selecting the one or more treatment agents from the list of available treatment agents.

216. The system of claim 195, further including circuitry for receiving user information from the individual.

217. The system of claim 216, wherein the circuitry for receiving the user information from the individual comprises circuitry for receiving age, gender, ethnicity, skin characteristics, geographical location, medical history, co-morbidities, or user preferences from the individual.

218. The system of claim 195, wherein the circuitry for arranging for the delivery of the selected one or more treatment agents comprises circuitry for automatically arranging for the delivery of the selected one or more treatment agents.

219. The system of claim 195, wherein the circuitry for arranging for the delivery of the selected one or more treatment agents comprises circuitry for arranging for the delivery of the selected one or more treatment agents to a street address.

220. The system of claim 195, wherein the circuitry for arranging for the delivery of the selected one or more treatment agents comprises circuitry for arranging for the delivery of the selected one or more treatment agents to a postal address.

221. The system of claim 195, wherein the circuitry for arranging for the delivery of the selected one or more treatment agents comprises circuitry for arranging for the delivery of the selected one or more treatment agents to a residence, a post office, a delivery service office, a store, a pharmacy, a medical office, or a cosmetic counter.

222. The system of claim 195, further comprising:

circuitry for arranging for delivery of one or more microbe sampling units.

223. The system of claim 195, further comprising:

circuitry for notifying the individual that delivery of the selected one or more treatment agents has been arranged.

224. The system of claim 223, wherein the circuitry for notifying the individual comprises circuitry for notifying the individual by at least one of an electronic communication, a telephonic communication, or a written communication.