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METHOD FOR DETERMINING GLUCOSE CONCENTRATION IN HUMAN BLOOD

  • US 20150073242A1
  • Filed: 08/22/2014
  • Published: 03/12/2015
  • Est. Priority Date: 02/24/2012
  • Status: Abandoned Application
First Claim
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1. A method of measuring of a concentration of blood glucose in a human, the method comprising:

  • using spaced apart electrodes attached to a region of a body of the human to successively measure values of high frequency impedance and low frequency impedance of the region at predetermined time intervals;

    using a measured value of the high frequency impedance to determine an estimate of a volume of fluid in tissue of the region between the electrodes;

    using a measured value of the low frequency impedance to determine an estimate of a volume of an extracellular fluid in the tissue in the region between the electrodes;

    determining an increment of a metabolic component of the volume of the extracellular fluid by;

    determining an increment of the estimate of the volume of the fluid relative to a previously measured value of the volume of the fluid;

    determining an increment of the estimate of the volume of the extracellular fluid relative to a previously measured value of the volume of the extracellular fluid;

    determining a difference between the increment of the estimate of the volume of the fluid and the increment of the estimate of the volume of the extracellular fluid;

    determining an increment of the concentration of the blood glucose by normalizing the increment of the metabolic component of the volume of the extracellular fluid; and

    determining the concentration of the blood glucose by adding up the increment of the concentration of the blood glucose and a previously determined concentration of the blood;

    wherein determining a concentration of the blood glucose at a first time interval comprises adding up an increment of the concentration at the first interval of time and an initial blood glucose concentration.

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