BIOLOGICAL INFORMATION MEASUREMENT DEVICE AND BIOLOGICAL INFORMATION MEASUREMENT METHOD USING SAME

• US 20150087940A1
• Filed: 04/25/2013
• Published: 03/26/2015
• Est. Priority Date: 05/07/2012
• Status: Active Grant

• Current Assignee: PHC Holdings Corporation
• Original Assignee: Panasonic Healthcare Company Limited (PHC Holdings Corporation)
• Inventors: Yoshioka, Eriko, Tatemoto, Susumu
• Granted Patent: US 9,629,577 B2
• Time in Patent Office: Days
• US Class Current: 600/345
• CPC Class Codes: A61B 5/14517 for sweat
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14535 for measuring haematocrit
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/14735 comprising an immobilised reagent
• CPC Class Codes: G01N 27/3274 Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration coding of calibration information G01N33/48771
• CPC Class Codes: G01N 33/49 Blood chemical methods for determining blood cell populations G01N33/5094; chemical analysis of blood groups or blood types G01N33/80

Abstract

The present invention relates to a biological information measurement device and a biological information measurement method using the same, and is intended to allow appropriate measurement to be carried out. In the biological information measurement device of the present invention, a control unit 18 is allowed to execute a pre-processing voltage application mode A and a biological information measurement mode C. Furthermore, in the biological information measurement device of the present invention, the hematocrit value of blood is calculated in either the pre-processing voltage application mode A or the biological information measurement mode C, and according to the hematocrit value thus calculated, the duration for applying a measuring voltage upon and after the calculation of the hematocrit value is modified.

Claims

1. A biological information measurement device, to which a biosensor is attached, the biosensor comprising a first electrode and a second electrode, a reagent portion provided between the first electrode and the second electrode, and a guide portion for guiding blood to the reagent portion,

wherein the biological information measurement device comprises:

a first input terminal, to which the first electrode is connected, and a second input terminal, to which the second electrode is connected,

a voltage applying unit for applying a voltage to the first input terminal and the second input terminal, and

a control unit connected to the voltage applying unit,

the control unit is configured to execute;

a pre-processing voltage application mode, in which the voltage applying unit applies a pre-processing voltage to the first input terminal and the second input terminal, and

a biological information measurement mode, in which after the pre-processing voltage application mode, the voltage applying unit applies a measuring voltage to the first input terminal and the second input terminal to measure biological information, and

the control unit has a configuration, in which the hematocrit value of the blood is calculated in either the pre-processing voltage application mode or the biological information measurement mode, and according to the hematocrit value thus calculated, the duration for applying the measuring voltage to the first input terminal and the second input terminal upon and after the calculation of the hematocrit value is modified.

2. The biological information measurement device according to claim 1, wherein the control unit has a configuration, in which when the hematocrit value calculated exceeds 55%, the control unit increases the duration for applying the measuring voltage in the biological information measurement mode as compared to the case where the hematocrit value is 55% or lower.

3. The biological information measurement device according to claim 1, wherein a third electrode is provided opposite to the guide portion for the first electrode and the second electrode, the third electrode is configured to be connected to a third input terminal of the biological information measurement device, the third input terminal is connected to the control unit, and the control unit executes a blood arrival detection mode, in which it is detected that the blood has reached the reagent portion prior to the pre-processing voltage application mode.

4. The biological information measurement device according to claim 1, further comprising a determination unit connected to the first input terminal and the second input terminal,

wherein the determination unit is connected to the control unit, and

the determination unit compares the current flowing between the first electrode and the second electrode with a threshold value through the first input terminal and the second input terminal.

5. A method of measuring biological information using a biological information measurement device according to claim 1,

wherein in either the pre-processing voltage application mode or the biological information measurement mode, the hematocrit value of the blood is calculated, and

then according to the hematocrit value thus calculated, the duration for applying the measuring voltage upon and after the calculation of the hematocrit value is set.

6. A biological information measurement device, to which a biosensor is attached, the biosensor comprising a first electrode and a second electrode, a reagent portion provided between the first electrode and the second electrode, and a guide portion for guiding blood to the reagent portion,

wherein the biological information measurement device comprises:

a first input terminal, to which the first electrode is connected, and a second input terminal, to which the second electrode is connected,

a voltage applying unit for applying a voltage to the first input terminal and the second input terminal, and

a control unit connected to the voltage applying unit,

the control unit is configured to execute;

a pre-processing voltage application mode, in which the voltage applying unit applies a pre-processing voltage to the first input terminal and the second input terminal,

a voltage application pause mode, in which after the pre-processing voltage application mode, the voltage applying unit pauses the voltage application to the first input terminal and the second input terminal, and

a biological information measurement mode, in which after the voltage application pause mode, the voltage applying unit applies a measuring voltage to the first input terminal and the second input terminal to measure biological information, and

the control unit has a configuration, in which the hematocrit value of the blood is calculated in an early stage of the biological information measurement mode and according to the hematocrit value thus calculated, the duration for applying the measuring voltage upon and after the calculation of the hematocrit value is modified.

7. The biological information measurement device according to claim 6, wherein the control unit has a configuration, in which when the hematocrit value calculated exceeds 55%, the control unit increases the duration for applying the measuring voltage in the biological information measurement mode as compared to the case where the hematocrit value is 55% or lower.

8. The biological information measurement device according to claim 6, wherein a third electrode is provided opposite to the guide portion for the first electrode and the second electrode, the third electrode is configured to be connected to a third input terminal of the biological information measurement device, the third input terminal is connected to the control unit, and the control unit executes a blood arrival detection mode, in which it is detected that the blood has reached the reagent portion prior to the pre-processing voltage application mode.

9. The biological information measurement device according to claim 6, further comprising a determination unit connected to the first input terminal and the second input terminal,

wherein the determination unit is connected to the control unit, and

the determination unit compares the current flowing between the first electrode and the second electrode with a threshold value through the first input terminal and the second input terminal.

10. A method of measuring biological information using a biological information measurement device according to claim 6,

wherein a pre-processing voltage is applied to the first input terminal and the second input terminal from the voltage applying unit,

then the voltage application to the first input terminal and the second input terminal is paused,

thereafter, the measuring voltage is applied to the first input terminal and the second input terminal,

in an early stage of applying the measuring voltage, a hematocrit value of the blood is calculated, and

then according to the hematocrit value thus calculated, the duration for applying the measuring voltage upon and after the calculation of the hematocrit value is set.