DELIVERY OF GASES TO THE NASAL AIRWAY

• US 20150090259A1
• Filed: 12/04/2014
• Published: 04/02/2015
• Est. Priority Date: 07/25/2006
• Status: Abandoned Application

• Current Assignee: OptiNose AS (OptiNose, Inc.)
• Original Assignee: OptiNose AS (OptiNose, Inc.)
• Inventors: DJUPESLAND, Per Gisle, Hafner, Roderick Peter
• Application Number:
  US14/560,053
• Publication Number:
  US 20150090259A1
• Time in Patent Office: Days
• US Class Current: 128/202.26
• CPC Class Codes: A61M 15/0003 with means for dispensing more than one drug
• CPC Class Codes: A61M 15/0028 using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
• CPC Class Codes: A61M 15/0065 Inhalators with dosage or measuring devices A61M15/0028 takes precedence; dosage devices incorporated in aerosol cans B65D83/52
• CPC Class Codes: A61M 15/0098 Activated by exhalation
• CPC Class Codes: A61M 15/025 Bubble jet droplet ejection devices
• CPC Class Codes: A61M 15/08 Inhaling devices inserted into the nose
• CPC Class Codes: A61M 16/0003 Accessories therefor, e.g. sensors, vibrators, negative pressure
• CPC Class Codes: A61M 16/0057 Pumps therefor
• CPC Class Codes: A61M 16/0672 Nasal cannula assemblies for oxygen therapy
• CPC Class Codes: A61M 16/0808 Condensation traps
• CPC Class Codes: A61M 16/101 using an oxygen concentrator
• CPC Class Codes: A61M 16/122 with dilution
• CPC Class Codes: A61M 16/142 with semi-permeable walls separating the liquid from the respiratory gas
• CPC Class Codes: A61M 16/22 Carbon dioxide-absorbing devices ; Other means for removing carbon dioxidecartridges with absorbing substances for respiratory apparatus A62B19/00
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0027 pressure meter
• CPC Class Codes: A61M 2016/003 with a flowmeter
• CPC Class Codes: A61M 2016/0042 in the expiratory circuit
• CPC Class Codes: A61M 2202/0208 Oxygen
• CPC Class Codes: A61M 2202/0225 Carbon oxides, e.g. Carbon dioxide
• CPC Class Codes: A61M 2202/025 : Helium
• CPC Class Codes: A61M 2202/0266 : Nitrogen (N)
• CPC Class Codes: A61M 2202/0275 : Nitric oxide [NO]
• CPC Class Codes: A61M 2202/064 : Powder
• CPC Class Codes: A61M 2205/3334 : Measuring or controlling the flow rate
• CPC Class Codes: A61M 2210/0625 : Mouth

Abstract

A delivery device for and a method of delivering gases to the nasal airway, in particular therapeutic gases and gases in combination with active substances, either as powders or liquids, for enhanced uptake of the active substances.

Claims

1. A delivery device for providing a therapeutic gas to the nasal airway of a subject, the delivery device comprising:

a nosepiece for fitting to one nostril of the subject;

a mouthpiece through which the subject in use exhales and which is fluidly connected to the nosepiece; and

a scrubber which is operative at least to reduce the concentration of at least one gas from an exhaled breath of the subject as delivered through the mouthpiece and provide a gas flow to the nosepiece which has an increased concentration of at least one other, therapeutic gas which provides a therapeutic effect.

2. The delivery device of claim 1, wherein the scrubber is operative to reduce the concentration of at least two gases from an exhaled breath of the subject.

3. The delivery device of claim 1, wherein the at least one gas comprises nitrogen.

4. The delivery device of claim 1, wherein the at least one gas comprises oxygen.

5. The delivery device of claim 1, wherein the at least one other, therapeutic gas comprises oxygen.

6. The delivery device of claim 1, wherein the at least one gas comprises carbon dioxide.

7. The delivery device of claim 1, wherein the at least one other, therapeutic gas comprises carbon dioxide.

8. The delivery device of claim 1, wherein the scrubber is operative to provide a gas flow which has a concentration of the at least one other, therapeutic gas of at least 10 vol %, optionally at least 15 vol %, optionally at least 20 vol %, optionally at least 30 vol %, optionally at least 40 vol %, and optionally at least 50 vol %.