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RNA-INTERFERENCE BY SINGLE-STRANDED RNA MOLECULES

  • US 20150096064A1
  • Filed: 07/22/2014
  • Published: 04/02/2015
  • Est. Priority Date: 07/10/2002
  • Status: Active Grant
First Claim
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16-1. The RISC according to claim 16, wherein said sulfur replaced monophosphate, diphosphate or triphosphate is 5′

  • -alpha-thiotriphosphate or 5′

    -gamma-thiotriphosphate, said 5′

    -alkylphosphonate is RP(OH)(O)-0-5′

    - or (OH)2(O)P-5′

    -CH2

    ), and said 5′

    -alkyletherphosphonate is RP(OH)(O)—

    O-5′

    -.

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