SYSTEM FOR HIGH RESOLUTION FAST ACQUISITION MAGNETIC RESONANCE IMAGING USING A CATHETER-MOUNTED COIL

• US 20150099965A1
• Filed: 10/07/2014
• Published: 04/09/2015
• Est. Priority Date: 10/07/2013
• Status: Abandoned Application

• Current Assignee: University of Utah Research Foundation (State of Utah)
• Original Assignee: University of Utah Research Foundation (State of Utah)
• Inventors: Hadley, J. Rock, Parker, Dennis Lee, Kholmovski, Evgueni G., Marrouche, Nassir F., Volland, Nelly A., Merrill, Robb Phillip
• Application Number:
  US14/508,070
• Publication Number:
  US 20150099965A1
• Time in Patent Office: Days
• US Class Current: 600/423
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 5/201 Assessing renal or kidney functions
• CPC Class Codes: A61B 5/6853 with a balloon
• CPC Class Codes: A61B 5/6858 with a distal basket, e.g. expandable basket
• CPC Class Codes: G01R 33/287 involving active visualization of interventional instruments, e.g. using active tracking RF coils or coils for intentionally creating magnetic field inhomogeneities
• CPC Class Codes: G01R 33/34084 implantable coils or coils being geometrically adaptable to the sample, e.g. flexible coils or coils comprising mutually movable parts
• CPC Class Codes: G01R 33/3657 Decoupling of multiple RF coils wherein the multiple RF coils do not have the same function in MR, e.g. decoupling of a transmission coil from a receive coil
• CPC Class Codes: G01R 33/3685 Means for reducing sheath currents, e.g. RF traps, baluns

Abstract

A catheter-mounted, expandable or set in position, coil for magnetic resonance imaging. The coil having a catheter sheath including an elongated tube with a central axis, the catheter sheath having an opening at an end thereof; an expandable coil including a conductive material connected to an expansion mechanism which, when deployed, maintains the expandable receive coil shape; and a cable running through the catheter sheath, the cable being electrically connected to the coil inductive loop.

Claims

1. An expandable catheter-mounted coil for magnetic resonance imaging, comprising:

a catheter sheath comprising an elongated tube with a central axis, the catheter sheath having an opening at an end thereof;

an expandable coil comprising a conductive material connected to an expansion mechanism which, when deployed, maintains the expandable coil shape; and

a cable running through the catheter sheath, the cable being electrically connected to the expandable coil.

2. The expandable catheter-mounted receive coil of claim 1, wherein the shape of the expandable coil is planar and wherein the plane of the expandable coil is perpendicular to the central axis of the catheter sheath.

3. The expandable catheter-mounted receive coil of claim 1, wherein the expansion mechanism comprises a first balloon, wherein the expandable coil is maintained in a position adjacent a perimeter of the first balloon, and wherein inflation of the first balloon maintains the expandable coil shape.

4. The expandable catheter-mounted receive coil of claim 3, wherein the first balloon is inflated with saline solution comprising MnCl₂.

5. The expandable catheter-mounted receive coil of claim 3, wherein the expandable receive coil is attached at a plurality of discrete locations to the perimeter of the first balloon.

6. The expandable catheter-mounted coil of claim 3, wherein expansion mechanism further comprises a second balloon and wherein the expandable receive coil is disposed between the first balloon and the second balloon.

7. The expandable catheter-mounted receive coil of claim 1, wherein the expansion mechanism comprises a plurality of resilient filaments slidingly disposed within the catheter sheath and biased away from the central axis, wherein the expandable coil is attached at an end of each filament, and wherein sliding the filaments out of the catheter sheath allows the filaments to move away from the central axis and maintain the expandable receive coil shape.

8. The expandable catheter-mounted coil of claim 1, wherein the cable comprises a coaxial cable.

9. The expandable catheter-mounted coil of claim 8, further comprising a phase shifter electrically connected to the cable.

10. The expandable catheter-mounted coil of claim 9, wherein the cable comprises a circuit electrically connected to the phase shifter, the cable, and the expandable coil, the circuit configured to perform at least one of matching, tuning, and decoupling.

11. The expandable catheter-mounted coil of claim 10, wherein the expandable coil is configured for use within a 3 Tesla MR coil.

12. The expandable catheter-mounted coil of claim 1, wherein the expandable inductive loop coil comprises gold or silver.

13. A method for performing magnetic resonance imaging, the method comprising the steps of:

providing a catheter sheath comprising an elongated tube with a central axis, the catheter sheath having an opening at an end thereof;

disposing a cable within the catheter sheath;

electrically connecting an expandable coil to the cable, the expandable coil comprising a conductive material connected to an expansion mechanism;

deploying the expansion mechanism to maintain the expandable coil shape; and

placing the expandable coil within a magnetic field to obtain data.

14. The method of claim 13, wherein the shape of expandable coil is planar and wherein the plane of the expandable coil is perpendicular to the central axis of the catheter sheath.

15. The method of claim 13, wherein the expansion mechanism comprises a first balloon, the method further comprising

maintaining the expandable coil in a position adjacent a perimeter of the first balloon, and inflating the first balloon to maintain the expandable coil shape.

16. The method of claim 15, further comprising inflating the first balloon with saline comprising MnCl₂.

17. The method of claim 15, further comprising attaching the expandable coil at a plurality of discrete locations to the perimeter of the first balloon.

18. The method of claim 15, wherein expansion mechanism further comprises a second balloon and wherein the expandable coil is disposed between the first balloon and the second balloon.

19. The method of claim 13, wherein the expansion mechanism comprises a plurality of resilient filaments slidingly disposed within the catheter sheath and biased away from the central axis, the method further comprising

attaching the expandable coil at an end of each filament, and

sliding the filaments out of the catheter sheath to allow the filaments to move away from the central axis and maintain the expandable receive coil shape.

20. The method of claim 13, wherein the cable comprises a coaxial cable.

21. The method of claim 20, further comprising electrically connecting a phase shifter to the cable.

22. The method of claim 21, further comprising electrically connecting a circuit to the phase shifter, the cable, and the expandable receive coil, the circuit configured to perform at least one of matching, tuning, and decoupling.

23. The method of claim 22, wherein the magnetic field is generated by a commercial MR scanner.

24. The method of claim 23, further comprising applying a gradient echo pulse sequence having an echo time of at least 6 ms.

25. The method of claim 24, further comprising obtaining a phase image.

26. The method of claim 25, further comprising performing MR thermometry using the phase image.

27. The method of claim 13, wherein the expandable coil comprises silver or gold.

28. A method for performing magnetic resonance imaging, the method comprising the steps of:

providing a catheter sheath comprising an elongated tube with a central axis, the catheter sheath having an opening at an end thereof;

disposing a cable within the catheter sheath;

electrically connecting a coil to the cable, the coil comprising a conductive material;

maintaining the coil shape; and

locating the catheter sheath with the coil within a magnetic field to obtain data.

29. The method of claim 28, further comprising applying a gradient echo pulse sequence having an echo time of at least 6 ms.

30. The method of claim 29, further comprising obtaining a phase image.

31. The method of claim 30, further comprising performing MR thermometry using the phase image.

32. The method of claim 28, wherein the cable comprises a coaxial cable.

33. The method of claim 32, further comprising electrically connecting a phase shifter to the cable.

34. The method of claim 33, further comprising electrically connecting a circuit to the phase shifter, the cable, and the coil, the circuit configured to perform at least one of matching, tuning, and decoupling.

35. The method of claim 28, wherein locating the catheter sheath with the coil within a magnetic field to obtain data further comprises locating the catheter sheath within a renal artery of a patient.