FILTER AND NEUTRON BEAM SOURCE INCLUDING THE SAME

• US 20150105604A1
• Filed: 10/10/2014
• Published: 04/16/2015
• Est. Priority Date: 10/15/2013
• Status: Active Grant

• Current Assignee: Heron Neutron Medical Corp.
• Original Assignee: Industrial Technology Research Institute, National Tsing Hua University
• Inventors: LIU, Yen-Wan Hsueh, YOU, Zhen-Fan
• Granted Patent: US 9,789,340 B2
• Time in Patent Office: Days
• US Class Current: 600/1
• CPC Class Codes: A61N 2005/109 Neutrons
• CPC Class Codes: A61N 2005/1095 Elements inserted into the radiation path within the system, e.g. filters or wedges
• CPC Class Codes: A61N 5/1077 Beam delivery systems
• CPC Class Codes: G21G 4/02 Neutron sources
• CPC Class Codes: G21K 1/10 Scattering devices; Absorbing devices; Ionising radiation filters

Abstract

Disclosed is a filter including a second layer disposed between a first layer and a third layer. The first layer is composed of iron. The second layer is composed of 1 part by volume of lithium fluoride, 20 to 50 parts by volume of aluminum, and 50 to 80 parts by volume of aluminum fluoride. The third layer is composed of 1 part by weight of lithium fluoride and 99 to 100 parts by weight of magnesium fluoride.

Claims

1. A filter, comprising:

a first layer composed of iron;

a second layer composed of 1 part by volume of lithium fluoride, 20 to 50 parts by volume of aluminum, and 50 to 80 parts by volume of aluminum fluoride; and

a third layer composed of 1 part by weight of lithium fluoride and 99 to 100 parts by weight of magnesium fluoride,

wherein the second layer is disposed between the first layer and the third layer.

2. The filter as claimed in claim 1, wherein the filter has a total thickness of 67.5 cm to 70 cm, and a circular cross-section with a radius of 40 cm to 60 cm.

3. The filter as claimed in claim 1, wherein the first layer has a thickness of 25 cm to 40 cm, the second layer has a thickness of 10 cm to 37.5 cm, and the third layer has a thickness of 5 cm to 20 cm.

4. A neutron beam source, comprising:

an accelerator;

a beryllium target; and

the filter as claimed in claim 1,

wherein the beryllium target is disposed between the accelerator and the filter, and the first layer of the filter is disposed between the beryllium target and the third layer.

5. The neutron beam source as claimed in claim 4, wherein:

the accelerator produces a proton beam of 30 MeV/1 mA, the first layer of the filter has a thickness of 25 cm to 40 cm, the second layer of the filter has a thickness of 10 cm to 37.5 cm, and the third layer of the filter has a thickness of 5 cm to 20 cm.

6. The neutron beam source as claimed in claim 4, wherein:

the accelerator produces a proton beam of 29 MeV/1 mA, the first layer of the filter has a thickness of 25 cm to 37.5 cm, the second layer of the filter has a thickness of 12.5 cm to 37.5 cm, and the third layer of the filter has a thickness of 5 cm to 17.5 cm.

7. The neutron beam source as claimed in claim 4, wherein:

the accelerator produces a proton beam of 31 MeV/1 mA, the first layer of the filter has a thickness of 27.5 cm to 40 cm, the second layer of the filter has a thickness of 10 cm to 35 cm, and the third layer of the filter has a thickness of 7.5 cm to 20 cm.

8. The neutron beam source as claimed in claim 4, wherein:

the accelerator produces a proton beam of 30 MeV/1 mA for colliding the beryllium target to form neutrons; and

the neutrons pass through the filter to form a moderated neutron beam, wherein the moderated neutron beam has an epithermal neutron flux of 1.7×

10⁹ n cm<sup>−

2</sup>s<sup>−

1</sup> to 1.9×

10⁹ n cm<sup>−

2</sup>s<sup>−

1</sup>, and a fast neutron dose component of 2.9×

10<sup>−

11</sup> cGy cm² to 3.5×

10<sup>−

11</sup> cGy cm² per epithermal neutron.

9. The neutron beam source as claimed in claim 4, wherein:

the accelerator produces a proton beam of 29 MeV/1 mA for colliding the beryllium target to form neutrons; and

the neutrons pass through the filter to form a moderated neutron beam, wherein the moderated neutron beam has an epithermal neutron flux of 1.7×

10⁹ n cm<sup>−

2</sup>s<sup>−

1</sup> to 1.9×

10⁹ n cm<sup>−

2</sup>s<sup>−

1</sup>, and a fast neutron dose component of 2.9×

10<sup>−

11</sup> cGy cm² to 3.5×

10<sup>−

11</sup> cGy cm² per epithermal neutron.

10. The neutron beam source as claimed in claim 4, wherein:

the accelerator produces a proton beam of 31 MeV/1 mA for colliding the beryllium target to form neutrons; and

the neutrons pass through the filter to form a moderated neutron beam, wherein the moderated neutron beam has an epithermal neutron flux of 1.7×

10⁹ n cm<sup>−

2</sup>s<sup>−

1</sup> to 1.9×

10⁹ n cm<sup>−

2</sup>s<sup>−

1</sup>, and a fast neutron dose component of 2.9×

10<sup>−

11</sup> cGy cm² to 3.7×

10<sup>−

11</sup> cGy cm² per epithermal neutron.

11. The neutron beam source as claimed in claim 4, further comprising a collimator element, wherein the filter is disposed between the beryllium target and the collimator element.

12. The neutron beam source as claimed in claim 11, wherein:

the accelerator produces a proton beam of 30 MeV/1 mA for colliding the beryllium target to form neutrons; and

the neutrons pass through the filter and the collimator to form a moderated neutron beam, wherein the moderated neutron beam has an epithermal neutron flux of 1.7×

10⁹ n cm<sup>−

2</sup>s<sup>−

1</sup> to 2.0×

10⁹ n cm<sup>−

2</sup>s<sup>−

1</sup>, and a fast neutron dose component of 2.0×

10<sup>−

11</sup> cGy cm² to 2.6×

10<sup>−

11</sup> cGy cm² per epithermal neutron.

13. The neutron beam source as claimed in claim 11, wherein:

the accelerator produces a proton beam of 30 MeV/2 mA for colliding the beryllium target to form neutrons; and

the neutrons pass through the filter and the collimator to form a moderated neutron beam, wherein the moderated neutron beam has an epithermal neutron flux of 3.4×

10⁹ n cm<sup>−

2</sup>s<sup>−

1</sup> to 4.0×

10⁹ n cm<sup>−

2</sup>s<sup>−

1</sup>, and a fast neutron dose component of 2.0×

10<sup>−

11</sup> cGy cm² to 2.6×

10<sup>−

11</sup> cGy cm² per epithermal neutron.

14. The neutron beam source as claimed in claim 4, further comprising a lead wall surrounding sidewalls of the filter.

15. The neutron beam source as claimed in claim 14, wherein the lead wall has a thickness of greater than or equal to 15 cm.

16. The neutron beam source as claimed in claim 4 being applied to accelerator-based boron neutron capture therapy.