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High Speed Molecular Sensing with Nanopores

  • US 20150111779A1
  • Filed: 10/23/2014
  • Published: 04/23/2015
  • Est. Priority Date: 10/23/2013
  • Status: Active Grant
First Claim
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1. A method for molecular counting and/or sorting, comprising:

  • a. providing an array of nanopores, wherein an individual nanopore of said array is individually addressable by an adjacent sensing electrode;

    b. providing a plurality of markers that each comprise nucleotides, wherein at least two of the nucleotides hybridize with a nucleic acid sample, and wherein the markers are capable of being captured by the individual nanopore and identified using the sensing electrode; and

    c. capturing and identifying the markers with the array of nanopores at a rate of at least about 1 marker per second per nanopore.

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