ANALYSIS OF ELECTROCARDIOGRAM SIGNALS

• US 20150112218A1
• Filed: 12/28/2014
• Published: 04/23/2015
• Est. Priority Date: 05/17/2005
• Status: Active Grant

• Current Assignee: BIO Signal Analysis Ltd.
• Original Assignee: BIO Signal Analysis Ltd.
• Inventors: SHANI, Benjamin, REVZEN, Shai, FRIMERMAN, Aaron
• Granted Patent: US 9,468,391 B2
• Time in Patent Office: Days
• US Class Current: 600/516
• CPC Class Codes: A61B 5/25 Bioelectric electrodes therefor
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/339 Displays specially adapted therefor
• CPC Class Codes: A61B 5/341 Vectorcardiography [VCG]
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61B 5/364 Detecting abnormal ECG interval, e.g. extrasystoles, ectopic heartbeats

Abstract

A method for graphical representation of a train of ECG complexes having an R wave and a T-P interval and having variable isoelectric baselines. The method involves aligning the complexes in terms of signal amplitude by obtaining a baseline, thereby to provide a graphical representation of said train of ECG complexes; and aligning said complexes temporally using corresponding predetermined points.

Claims

1. Apparatus for graphical representation of a train of ECG complexes, each of said electrocardiogram (ECG) complexes respectively comprising an R wave and a T-P interval and having respectively variable isoelectric baselines, the apparatus comprising:

electrodes;

an isoelectric alignment unit configured to obtain electrocardiogram (ECG) signals from said electrodes when said electrodes are placed on a subject and to carry out an alignment for each complex comprising aligning said complexes in terms of signal amplitude by obtaining a respective T-P interval for each ECG complex, using said T-P interval to infer said respective isoelectric baseline and aligning said isoelectric baselines; and

a temporal alignment unit configured to align said complexes temporally using a predetermined point on respective R-waves, thereby to graphically represent said train of ECG complexes as a superposition of said ECG complexes into a single complex.

2. Apparatus for graphical representation of a train of ECG complexes, said ECG complexes respectively comprising an R wave and a T-P interval, each said ECG complex further comprising a respectively variable isoelectric baseline, the apparatus comprising:

electrodes configured to be placed on a subject;

an isoelectric alignment unit configured to obtain an overall alignment baseline for aligning all ECG complexes of said train, and to align said complexes to said overall alignment baseline, said isolectric alignment unit configured to obtain said overall alignment baseline using irregular sampling of said electrodes to obtain varying isolectric baselines, said isoelectric alignment unit configured to provide splines for said irregular sampling; and

a temporal alignment unit configured to carry out temporal aligning of said complexes using a predetermined point of respective complexes, thereby to provide said graphical representation of said train of ECG complexes.

3. Apparatus according to claim 2, wherein said temporal alignment unit is adapted to carry out said aligning based on at least one of a group comprising respective R waves, respective S waves, and any recurring feature.

4. Apparatus according to claim 2, further comprising a superposition unit for superimposing said complexes by plotting for each complex a predetermined time interval preceding said predetermined point and a predetermined time following said predetermined point.

5. Apparatus according to claim 4, further comprising a log unit for calculating log values for said plots and assigning visual indicators based on said assigned log values.

6. Apparatus according to claim 4, further comprising a color assignment unit for assigning colors to respective plots, thereby to indicate one of a plurality of groups to which a respective plot may belong.

7. Apparatus according to claim 2, further comprising a display unit for displaying said superimposed ECG complexes to show a variation over a period of time of ECG complexes in a group.

8. Apparatus according to claim 7, wherein said display unit is configured to display a signal variation indicator along with said superimposed ECG complexes.

9. Apparatus according to claim 2, wherein said isoelectric alignment unit comprises a bandpass filter with asymmetric treatment of out of band signals, or wherein said isoelectric alignment unit comprises a first lowpass filter for obtaining a raw baseline, a subtraction unit for subtracting said raw baseline and a second lowpass filter for smoothing.

10. Apparatus according to claim 2, wherein said train is obtained from each one of a plurality of leads at different locations on a subject and wherein said graphical representation comprises a common alignment for each one of said plurality of leads.

11. Apparatus according to claim 2, comprising an oversampling feature for obtaining said train of ECG complexes using a sampling rate in excess of 1 KHz.

12. Apparatus according to claim 2, wherein said isoelectric alignment unit is configured to carry out said aligning of respective T-P intervals by use of a smooth interpolator.

13. Apparatus according to claim 12, wherein said smooth interpolator comprises one member of the group consisting of:

polynomial splines, polynomial cubic hermite splines, an association with knot points generated from linear regression of respective t-p intervals, and an association with knot points generated from regression of respective t-p intervals.

14. Apparatus according to claim 8, wherein said display unit is configured to use coloration as said signal variation indicator.

15. Apparatus according to claim 7, wherein said display unit is configured to use color separation between a short beat and long beat.

16. Apparatus according to claim 7, wherein said display unit is further configured to display an R-R time plot.